Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells (Q24317653)

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

MDS1 and EVI1 complex locus

GOA release 2020-03-11

1 reference

ORCID Public Data File 2021

GOA release 2020-03-11

1 reference

1 reference

author name string

M Shimabe

1

0 references

S Goyama

2

0 references

N Watanabe-Okochi

3

0 references

A Yoshimi

4

0 references

M Ichikawa

5

0 references

Y Imai

6

0 references

M Kurokawa

High EVI1 expression predicts poor survival in acute myeloid leukemia: a study of 319 de novo AML patients

7

0 references

language of work or name

English

0 references

publication date

10 December 2009

0 references

published in

Oncogene

0 references

volume

28

0 references

issue

49

0 references

page(s)

4364-74

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Evi1 is a survival factor which conveys resistance to both TGFbeta- and taxol-mediated cell death via PI3K/AKT

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Identification of binding sites of EVI1 in mammalian cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/ONC.2009.288

Four of the seven zinc fingers of the Evi-1 myeloid-transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Pathogenetic significance of ecotropic viral integration site-1 in hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Evi-1 is a critical regulator for hematopoietic stem cells and transformed leukemic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

The human t(1;19) translocation in pre-B ALL produces multiple nuclear E2A-Pbx1 fusion proteins with differing transforming potentials

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Significant increase of self-renewal in hematopoietic cells after forced expression of EVI1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

EVI1 Impairs myelopoiesis by deregulation of PU.1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

The role of HOX homeobox genes in normal and leukemic hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Chromatin immunoprecipitation and microarray-based analysis of protein location

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

AP-2alpha selectively regulates fragile X mental retardation-1 gene transcription during embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

The specificity of homeotic gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Evi-1, a murine zinc finger proto-oncogene, encodes a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Transformation of bone marrow B-cell progenitors by E2a-Hlf requires coexpression of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

AML1-Evi-1 specifically transforms hematopoietic stem cells through fusion of the entire Evi-1 sequence to AML1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Prognostically useful gene-expression profiles in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

AML1 mutations induced MDS and MDS/AML in a mouse BMT model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Identification of novel functional regions important for the activity of HOXB7 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Clinical correlations of the 3q21;q26 cytogenetic anomaly. A leukemic or myelodysplastic syndrome with preserved or increased platelet production and lack of response to cytotoxic drug therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.288

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.288

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

220396

1019935975

0 references

220396

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference