Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice (Q38668055)

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scientific article published on 28 September 2015

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English	Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice	scientific article published on 28 September 2015

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PMC publication ID

5 September 2017

Receptor Protein Tyrosine Phosphatase α-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice (English)

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5 September 2017

Mattias D Svensson

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Piotr Mydel

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Stephanie M Stanford

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Cristiano Sacchetti

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Caila A Pilo

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Dennis J Wu

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William B Kiosses

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Annelie Hellvard

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Brith Bergum

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German R Aleman Muench

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Christian Elly

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Jeroen den Hertog

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Ari Elson

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Jan Sap

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David L Boyle

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Maripat Corr

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Gary S Firestein

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Nunzio Bottini

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28 September 2015

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5 September 2017

Arthritis & Rheumatology

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359-369

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Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis

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Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

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Protein tyrosine phosphatase α mediates profibrotic signaling in lung fibroblasts through TGF-β responsiveness.

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Grb2 promotes integrin-induced focal adhesion kinase (FAK) autophosphorylation and directs the phosphorylation of protein tyrosine phosphatase α by the Src-FAK kinase complex

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The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity

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The interaction between CXCL10 and cytokines in chronic inflammatory arthritis

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Antiinflammatory functions of p38 in mouse models of rheumatoid arthritis: advantages of targeting upstream kinases MKK-3 or MKK-6

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Rheumatoid arthritis progression mediated by activated synovial fibroblasts

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Therapeutic opportunities in fibroblasts in inflammatory arthritis

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6 September 2017

Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1-induced matrix metalloproteinase-3 expression

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6 September 2017

Platelets amplify inflammation in arthritis via collagen-dependent microparticle production

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Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

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6 September 2017

Synovial fibroblasts spread rheumatoid arthritis to unaffected joints

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6 September 2017

Protein-tyrosine phosphatase-alpha and Src functionally link focal adhesions to the endoplasmic reticulum to mediate interleukin-1-induced Ca2+ signaling.

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The arthritis severity locus Cia5d is a novel genetic regulator of the invasive properties of synovial fibroblasts

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The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

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6 September 2017

Differential expression of the FAK family kinases in rheumatoid arthritis and osteoarthritis synovial tissues

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RPTPalpha is essential for NCAM-mediated p59fyn activation and neurite elongation.

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A novel mechanism for the regulation of IFN-gamma inducible protein-10 expression in rheumatoid arthritis

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PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration

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TGFβ responsive tyrosine phosphatase promotes rheumatoid synovial fibroblast invasiveness.

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Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-

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31 August 2018

Arthritis critically dependent on innate immune system players

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31 August 2018

Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis.

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31 August 2018

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31 August 2018

Invasiveness of fibroblast-like synoviocytes is an individual patient characteristic associated with the rate of joint destruction in patients with rheumatoid arthritis

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Receptor protein tyrosine phosphatase alpha activates Src-family kinases and controls integrin-mediated responses in fibroblasts

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12 December 2020

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10.1002/ART.39442

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