Type I interferon dysregulation and neurological disease (Q38573095)

4 September 2017

Type I interferon dysregulation and neurological disease (English)

1 reference

4 September 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Andrew Jackson

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Alexa Jury

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

David Hunt

series ordinal

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

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publication date

25 August 2015

1 reference

4 September 2017

Nature Reviews Neurology

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26303851%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

515-523

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https://scigraph.springernature.com/pub.10.1038/nrneurol.2015.143

1 June 2020

exact match

0 references

cites work

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Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes

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Type I interferonopathies: a novel set of inborn errors of immunity

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Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia

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Molecular and functional analysis of an interferon gene from the zebrafish, Danio rerio

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Atlantic Salmon Interferon Genes: Cloning, Sequence Analysis, Expression, and Biological Activity

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Distinct evolution process among type I interferon in mammals

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Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.

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Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells

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Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination

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TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification

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RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

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Type I interferon receptors: biochemistry and biological functions.

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Complex modulation of cell type-specific signaling in response to type I interferons

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Interferon-stimulated genes and their antiviral effector functions

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A diverse range of gene products are effectors of the type I interferon antiviral response

21 January 2018

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Positive feedback regulation of type I interferon by the interferon-stimulated gene STING.

21 January 2018

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Negative feedback regulation of RIG-I-mediated antiviral signaling by interferon-induced ISG15 conjugation

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Human MxA protein: an interferon-induced dynamin-like GTPase with broad antiviral activity

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Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes

21 January 2018

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Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers

21 January 2018

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Missorting of LaCrosse virus nucleocapsid protein by the interferon-induced MxA GTPase involves smooth ER membranes

21 January 2018

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INTERFEROME: the database of interferon regulated genes

21 January 2018

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Functional role of type I and type II interferons in antiviral defense

21 January 2018

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Local type I IFN receptor signaling protects against virus spread within the central nervous system

21 January 2018

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Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon Beta producers that protect from lethal encephalitis

21 January 2018

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Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha

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Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study

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Herpes Simplex Virus in Children

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Diagnosis and surveillance of herpes simplex virus infection of the central nervous system

21 January 2018

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Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood

21 January 2018

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Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

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A novel form of human STAT1 deficiency impairing early but not late responses to interferons

21 January 2018

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Herpes simplex virus encephalitis in human UNC-93B deficiency

21 January 2018

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

21 January 2018

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TLR3 deficiency in patients with herpes simplex encephalitis

21 January 2018

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Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

21 January 2018

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An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

21 January 2018

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A progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis

21 January 2018

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Intrathecal synthesis of interferon-alpha in infants with progressive familial encephalopathy.

21 January 2018

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Assessment of interferon-related biomarkers in Aicardi-Goutières syndrome associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, and ADAR: a case-control study.

21 January 2018

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Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

21 January 2018

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Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

21 January 2018

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Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response

21 January 2018

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HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

21 January 2018

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Nucleic acid by-products and chronic inflammation

21 January 2018

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Nucleic acid-mediated inflammatory diseases

21 January 2018

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Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

21 January 2018

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Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

A type I interferon signature identifies bilateral striatal necrosis due to mutations in ADAR1.

21 January 2018

1 reference

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The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Clinical and molecular phenotype of Aicardi-Goutieres syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Intracerebral large artery disease in Aicardi-Goutières syndrome implicates SAMHD1 in vascular homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Cree encephalitis is allelic with Aicardi-Goutiéres syndrome: implications for the pathogenesis of disorders of interferon alpha metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Recognizable phenotypes associated with intracranial calcification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Two further cases of spondyloenchondrodysplasia (SPENCD) with immune dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Tartrate-resistant acid phosphatase deficiency causes a bone dysplasia with autoimmunity and a type I interferon expression signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Activated STING in a vascular and pulmonary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Complement in human diseases: Lessons from complement deficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Type I interferon in systemic lupus erythematosus and other autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Interferon and granulopoiesis signatures in systemic lupus erythematosus blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

21 January 2018

1 reference

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A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Familial systemic lupus erythematosus and congenital infection-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Phenotypic overlap between infantile systemic lupus erythematosus and Aicardi-Goutières syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

A mutation in TREX1 that impairs susceptibility to granzyme A-mediated cell death underlies familial chilblain lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Defective removal of ribonucleotides from DNA promotes systemic autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Aicardi-Goutières syndrome: a genetic microangiopathy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Cerebral thrombotic microangiopathy and antiphospholipid antibodies in Aicardi-Goutieres syndrome--report of two sisters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

C-terminal truncations in human 3'-5' DNA exonuclease TREX1 cause autosomal dominant retinal vasculopathy with cerebral leukodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Neuropathology and genetics of cerebroretinal vasculopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Evolution of a tumor-like lesion in cerebroretinal vasculopathy and TREX1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Multiple sclerosis-like lesions and type I interferon signature in a patient with RVCL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Heterozygous TREX1 mutations in early-onset cerebrovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome in relapsing-remitting multiple sclerosis patients on high-dose interferon β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Thrombotic microangiopathy associated with interferon beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Degos disease: a C5b-9/interferon-α-mediated endotheliopathy syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Aicardi-Goutières syndrome and the type I interferonopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Phenotypic variation in Aicardi-Goutières syndrome explained by cell-specific IFN-stimulated gene response and cytokine release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Trex1 prevents cell-intrinsic initiation of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

An autoimmune disease prevented by anti-retroviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

The enemy within: endogenous retroelements and autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Sifalimumab, a human anti-interferon-α monoclonal antibody, in systemic lupus erythematosus: a phase I randomized, controlled, dose-escalation study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Serum alpha interferon and lymphocyte inclusions in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Mx proteins: GTPases with antiviral activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Familial herpes simplex encephalitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Familial herpes encephalitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

TREX1 gene variant in neuropsychiatric systemic lupus erythematosus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Renal thrombotic microangiopathy induced by interferon-alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Safety profile and clinical activity of sifalimumab, a fully human anti-interferon α monoclonal antibody, in systemic lupus erythematosus: a phase I, multicentre, double-blind randomised study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2015.143

Mechanism of human MxA protein action: variants with changed antiviral properties

31 March 2020

1 reference

12 December 2020

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

1 reference

12 December 2020

Isolation of the virus of herpes simplex and the demonstration of intranuclear inclusions in a case of acute encephalitis

1 reference

12 December 2020

CpG-DNA-induced IFN-alpha production involves p38 MAPK-dependent STAT1 phosphorylation in human plasmacytoid dendritic cell precursors

1 reference

12 December 2020

Sero-epidemiological and -sociological patterns of herpes simplex virus infection in the world

1 reference

12 December 2020

Brain pathology in systemic lupus erythematosus

1 reference

12 December 2020

[Immunity and interference in vaccinia; inhibition of skin infection by inactivated virus]

1 reference

12 December 2020

Two cases of herpes simplex virus encephalitis in the same family.

1 reference

12 December 2020