ERK couples chronic survival of NK cells to constitutively activated Ras in lymphoproliferative disease of granular lymphocytes (LDGL). (Q38476727)

3 September 2017

title

ERK couples chronic survival of NK cells to constitutively activated Ras in lymphoproliferative disease of granular lymphocytes (LDGL). (English)

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3 September 2017

author name string

Pearlie K Epling-Burnette

1

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3 September 2017

Fanqi Bai

2

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3 September 2017

Sheng Wei

3

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3 September 2017

Pratima Chaurasia

4

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3 September 2017

Jeffrey S Painter

5

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3 September 2017

Nancy Olashaw

6

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3 September 2017

Andrew Hamilton

7

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3 September 2017

Said Sebti

8

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3 September 2017

Julie Y Djeu

9

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3 September 2017

Thomas P Loughran

10

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3 September 2017

language of work or name

English

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publication date

1 December 2004

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3 September 2017

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3 September 2017

volume

23

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3 September 2017

issue

57

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3 September 2017

page(s)

9220-9229

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208122

3 September 2017

exact match

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cites work

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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Mammalian MAP kinase signalling cascades

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Apoptosis and programmed cell death in immunity

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Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

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Dysregulated NK receptor expression in patients with lymphoproliferative disease of granular lymphocytes

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The intermediate filament protein keratin 8 is a novel cytoplasmic substrate for c-Jun N-terminal kinase.

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MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly

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Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells

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Human natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genes

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

21 January 2018

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Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

21 January 2018

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The "ex vivo" patterns of CD2/CD7, CD57/CD11c, CD38/CD11b, CD45RA/CD45RO, and CD11a/HLA-DR expression identify acute/early and chronic/late NK-cell activation states

21 January 2018

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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Leukemia of large granular lymphocytes: association with clonal chromosomal abnormalities and autoimmune neutropenia, thrombocytopenia, and hemolytic anemia

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Prototypical HTLV-I/II infection is rare in LGL leukemia

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Receptor-induced death in human natural killer cells: involvement of CD16.

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Lack of BLV and PTLV DNA sequences in the majority of patients with large granular lymphocyte leukaemia.

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Analysis of T-cell receptor gene rearrangement and expression in human natural killer clones

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Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

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Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8

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A retroviral-derived immunosuppressive peptide activates mitogen-activated protein kinases

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Chromosomal abnormalities define clonal proliferation in CD3- large granular lymphocyte leukemia

21 January 2018

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Characteristics of human large granular lymphocytes and relationship to natural killer and K cells

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MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

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Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

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Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2.

21 January 2018

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Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway

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Complex expression of natural killer receptor genes in single natural killer cells

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7 January 2021

In vivo activated cord blood lymphocytes express high affinity interleukin-2 receptor: evaluation of their responsiveness to in vitro stimulation with recombinant interleukin-2

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7 January 2021

Fulminant clonal expansion of large granular lymphocytes. Characterization of their morphology, phenotype, genotype, and function

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7 January 2021

The lymphoproliferative disease of granular lymphocytes. A heterogeneous disorder ranging from indolent to aggressive conditions

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7 January 2021

Dimensions Publication ID

Identifiers

DOI

10.1038/SJ.ONC.1208122

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1002447255

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1 reference