Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy (Q38363027)

2 September 2017

Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy (English)

1 reference

2 September 2017

Jeffery D Molkentin

5

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author name string

Eva van Rooij

1

1 reference

2 September 2017

Pieter A Doevendans

2

1 reference

2 September 2017

Chiel C de Theije

3

1 reference

2 September 2017

Fawzi A Babiker

4

1 reference

2 September 2017

Leon J de Windt

6

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2 September 2017

language of work or name

English

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publication date

10 September 2002

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

277

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2 September 2017

50

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2 September 2017

48617-48626

1 reference

The heart failure epidemic: exactly how big is it?

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin pathway is required for endothelin-1-mediated protection against oxidant stress-induced apoptosis in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Signaling pathways for cardiac hypertrophy and failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Stress pathways and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Left ventricular hypertrophy: pathogenesis, detection, and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Transcription factors of the NFAT family: regulation and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Two-site interaction of nuclear factor of activated T cells with activated calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin and beyond: cardiac hypertrophic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin and hypertrophic heart disease: novel insights and remaining questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Impaired long-chain fatty acid utilization by cardiac myocytes isolated from mice lacking the heart-type fatty acid binding protein gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Cloning and cellular distribution of a group II phospholipase A2 expressed in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: involvement of autocrine/paracrine pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

GATA4 mediates activation of the B-type natriuretic peptide gene expression in response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Requirement for transcription factor NFAT in interleukin-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

NFAT signaling: choreographing the social lives of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

NFAT signaling in vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Mechanisms of transactivation by nuclear factor of activated T cells-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Altered primary myogenesis in NFATC3(-/-) mice leads to decreased muscle size in the adult

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin signaling and muscle remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell su

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

NFAT4 movement in native smooth muscle. A role for differential Ca(2+) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

A second calcineurin binding site on the NFAT regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Cain, a novel physiologic protein inhibitor of calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Association of protein kinase A and protein phosphatase 2B with a common anchoring protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

The transcription factor NF-ATc is essential for cardiac valve formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin Expression, Activation, and Function in Cardiac Pressure-Overload Hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

Calcineurin Promotes Protein Kinase C and c-Jun NH2-terminal Kinase Activation in the Heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206532200

21 January 2018

Identifiers

DOI

10.1074/JBC.M206532200

1 reference

2 September 2017

1 reference