Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement (Q38359938)

2 September 2017

Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement (English)

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2 September 2017

Xu Y

1

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2 September 2017

Davidson L

series ordinal

2

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2 September 2017

Alt FW

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3

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2 September 2017

Baltimore D

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4

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2 September 2017

language of work or name

English

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publication date

1 April 1996

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2 September 2017

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2 September 2017

4

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2 September 2017

377-385

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2 September 2017

4

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Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

2 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Two regulatory elements for immunoglobulin kappa light chain gene expression

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

B cell development in mice that lack one or both immunoglobulin kappa light chain genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

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https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Dependence of enhancer-mediated transcription of the immunoglobulin mu gene on nuclear matrix attachment regions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Flow cytometric analysis of cell proliferation dynamics in the B cell compartment of the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Targeted disruption of mu chain membrane exon causes loss of heavy-chain allelic exclusion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

The v-abl tyrosine kinase negatively regulates NF-kappa B/Rel factors and blocks kappa gene transcription in pre-B lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Inducible gene targeting in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Targeted oncogene activation by site-specific recombination in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Protein-binding sites in Ig gene enhancers determine transcriptional activity and inducibility

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Mouse pre-B cells synthesize and secrete mu heavy chains but not light chains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

B cell-specific demethylation: a novel role for the intronic kappa chain enhancer sequence

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Production of homozygous mutant ES cells with a single targeting construct

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Ordered activation of the Ig lambda locus in Abelson B cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

A physical map and analysis of the murine C kappa-RS region show the presence of a conserved element

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Allelic exclusion in transgenic mice that express the membrane form of immunoglobulin mu

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Organization and expression of immunoglobulin genes in fetal liver hybridomas

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Immunoglobulin gene transcription is activated by downstream sequence elements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Helix-loop-helix transcription factor E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Synthesis of immunoglobulin mu chain gene products precedes synthesis of light chains during B-lymphocyte development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

B lymphocyte-specific protein binding near an immunoglobulin kappa-chain gene J segment

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980251-4

7 January 2021

10.1016/S1074-7613(00)80251-4

Identifiers

DOI

1 reference

2 September 2017

1 reference