Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus. (Q40875075)

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27 October 2019

title

Mutations of the intronic IgH enhancer and its flanking sequences differentially affect accessibility of the JH locus (English)

1 reference

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27 October 2019

author name string

J Chen

1

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27 October 2019

F Young

2

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27 October 2019

A Bottaro

3

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27 October 2019

V Stewart

4

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27 October 2019

R K Smith

5

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27 October 2019

F W Alt

6

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27 October 2019

publication date

1 December 1993

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27 October 2019

language of work or name

0 references

1 reference

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27 October 2019

volume

12

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issue

12

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27 October 2019

page(s)

4635-4645

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Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans

27 October 2019

cites work

1 reference

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V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer

24 September 2017

1 reference

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Receptor editing: an approach by autoreactive B cells to escape tolerance

24 September 2017

1 reference

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Receptor editing in self-reactive bone marrow B cells

24 September 2017

1 reference

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Somatic generation of antibody diversity

24 September 2017

1 reference

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Ordered rearrangement of immunoglobulin heavy chain variable region segments

24 September 2017

1 reference

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Introduced T cell receptor variable region gene segments recombine in pre-B cells: evidence that B and T cells use a common recombinase

24 September 2017

1 reference

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DNA methylation and gene activity

24 September 2017

1 reference

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

24 September 2017

1 reference

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T-cell antigen receptor genes and T-cell recognition

24 September 2017

1 reference

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The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements

24 September 2017

1 reference

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Mechanism and developmental program of immunoglobulin gene rearrangement in mammals

24 September 2017

1 reference

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The V(D)J recombination activating gene, RAG-1.

24 September 2017

1 reference

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Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Separate elements control DJ and VDJ rearrangement in a transgenic recombination substrate

24 September 2017

1 reference

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Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

24 September 2017

1 reference

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Immunoglobulin gene transcription

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Coordination of immunoglobulin DJH transcription and D-to-JH rearrangement by promoter-enhancer approximation

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Virus-transformed pre-B cells show ordered activation but not inactivation of immunoglobulin gene rearrangement and transcription

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Regulation of immunoglobulin gene transcription

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Transcriptional down-regulation of N-myc expression during B-cell development

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

RAG-1-deficient mice have no mature B and T lymphocytes

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

24 September 2017

1 reference

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A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

The essentials of DNA methylation

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck

24 September 2017

1 reference

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A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus

24 September 2017

1 reference

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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

15 June 2018

1 reference

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C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter

15 June 2018

1 reference

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VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=413901

Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription

19 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8223473

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8223473

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/J.1460-2075.1993.TB06152.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8223473%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8223473%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

PubMed publication ID

8223473

1 reference