Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts. (Q38354860)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

review article

1 reference

title

Molecular mechanism underlying the tumor-promoting functions of carcinoma-associated fibroblasts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Yanwen Zhang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Tanghong Jia

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Yuping Sun

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

publication date

15 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

1385-1394

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25680413%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s13277-015-3230-8

29 February 2020

exact match

0 references

cites work

Carcinoma-associated fibroblasts are a promising therapeutic target.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

'Cancer associated fibroblasts'--more than meets the eye.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Prognostic relevance of cancer-associated fibroblasts in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Senescence and the pro-tumorigenic stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Direct contacts with colon cancer cells regulate the differentiation of bone marrow mesenchymal stem cells into tumor associated fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Pericytes in kidney fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

21 January 2018

Fibroblasts in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Arousal of cancer-associated stroma: overexpression of palladin activates fibroblasts to promote tumor invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Podoplanin expressing cancer-associated fibroblasts in oral cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Stromal cells can contribute oncogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Differences between CAFs and their paired NCF from adjacent colonic mucosa reveal functional heterogeneity of CAFs, providing prognostic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Reciprocal interaction between carcinoma-associated fibroblasts and squamous carcinoma cells through interleukin-1α induces cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Activation of fibroblasts in cancer stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Accessories to the crime: functions of cells recruited to the tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Hallmarks of cancer: interactions with the tumor stroma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Carcinoma-associated fibroblasts promotes the proliferation of a lingual carcinoma cell line by secreting keratinocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Sonic hedgehog promotes desmoplasia in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Colorectal cancer cells activate adjacent fibroblasts resulting in FGF1/FGFR3 signaling and increased invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Expression of galectin-1 in carcinoma-associated fibroblasts promotes gastric cancer cell invasion through upregulation of integrin β1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Hedgehog signaling is active in human prostate cancer stroma and regulates proliferation and differentiation of adjacent epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

A role for cancer-associated fibroblasts in inducing the epithelial-to-mesenchymal transition in human tongue squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Extracellular matrix players in metastatic niches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour-stroma interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Matrix metalloproteinases and tumor metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Biophysical control of invasive tumor cell behavior by extracellular matrix microarchitecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Palladin promotes invasion of pancreatic cancer cells by enhancing invadopodia formation in cancer-associated fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Inflammation, carcinogenesis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Cancer associated fibroblasts express pro-inflammatory factors in human breast and ovarian tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

A pro-tumourigenic loop at the human prostate tumour interface orchestrated by oestrogen, CXCL12 and mast cell recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Transforming growth factor-β as a therapeutic target in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

A vaccine that co-targets tumor cells and cancer associated fibroblasts results in enhanced antitumor activity by inducing antigen spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-015-3230-8

Relationships of alpha-SMA-positive fibroblasts and SDF-1-positive tumor cells with neoangiogenesis in nasopharyngeal carcinoma

21 January 2018

1 reference

12 December 2020

Plasminogen activation and cancer

1 reference

12 December 2020

Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.

1 reference

12 December 2020

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

1 reference

12 December 2020

NPPB is a novel candidate biomarker expressed by cancer-associated fibroblasts in epithelial ovarian cancer

1 reference

12 December 2020

The carcinoma-associated fibroblast expressing fibroblast activation protein and escape from immune surveillance

1 reference

12 December 2020

Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

1 reference

12 December 2020

Stromal cell involvement in cancer.

1 reference

12 December 2020

Identification of fibroblast heterogeneity in the tumor microenvironment

1 reference

12 December 2020

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling.

1 reference

12 December 2020