Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling (Q38332220)

2 September 2017

Second site suppressor mutations of a GTPase-deficient G-protein alpha-subunit. Selective inhibition of Gbeta gamma-mediated signaling (English)

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2 September 2017

D M Apanovitch

1

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2 September 2017

T Iiri

2

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2 September 2017

T Karasawa

3

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2 September 2017

H R Bourne

4

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2 September 2017

H G Dohlman

5

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2 September 2017

language of work or name

English

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publication date

1 October 1998

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Journal of Biological Chemistry

2 September 2017

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2 September 2017

273

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2 September 2017

44

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2 September 2017

28597-28602

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Pertussis: current concepts of pathogenesis and prevention

2 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Abnormalities in G protein-coupled signal transduction pathways in human disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Expanding horizons for receptors coupled to G proteins: diversity and disease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Rapid GDP release from Gs alpha in patients with gain and loss of endocrine function

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Integrating genetic approaches into the discovery of anticancer drugs

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Regulation of membrane and subunit interactions by N-myristoylation of a G protein alpha subunit in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Plasmid construction by homologous recombination in yeast.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Gi2-mediated activation of the MAP kinase cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Fatty acylation of alpha z. Effects of palmitoylation and myristoylation on alpha z signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

G protein mutations that alter the pheromone response in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Conditional activation defect of a human Gsalpha mutant

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

RGS4 inhibits Gq-mediated activation of mitogen-activated protein kinase and phosphoinositide synthesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

A mutation that prevents GTP-dependent activation of the alpha chain of Gs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Functional analysis of a dominant negative mutant of G alpha i2.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

GPA1Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

The mating-specific G(alpha) protein of Saccharomyces cerevisiae downregulates the mating signal by a mechanism that is dependent on pheromone and independent of G(beta)(gamma) sequestration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

The 2.2 A crystal structure of transducin-alpha complexed with GTP gamma S

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Pheromone response in yeast

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Pharmaceutical research in molecular oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Micromanipulation and dissection of asci

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

Identification of common and distinct residues involved in the interaction of alphai2 and alphas with adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.44.28597

21 January 2018

Identifiers

DOI

10.1074/JBC.273.44.28597

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2 September 2017

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