A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death (Q38319762)

2 September 2017

A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death (English)

1 reference

2 September 2017

1 reference

1 reference

1 reference

Yabin Guo

1

1 reference

2 September 2017

Caifeng Chen

2

1 reference

2 September 2017

Yong Zheng

3

1 reference

2 September 2017

Jinchun Zhang

4

1 reference

2 September 2017

Xiaohui Tao

5

1 reference

2 September 2017

Shilian Liu

6

1 reference

2 September 2017

Dexian Zheng

7

1 reference

2 September 2017

Yanxin Liu

8

1 reference

2 September 2017

language of work or name

English

0 references

publication date

18 October 2005

1 reference

Journal of Biological Chemistry

2 September 2017

1 reference

2 September 2017

280

1 reference

2 September 2017

51

1 reference

2 September 2017

41940-41952

1 reference

Identification and characterization of a new member of the TNF family that induces apoptosis

2 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

The receptor for the cytotoxic ligand TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Safety and antitumor activity of recombinant soluble Apo2 ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Four deaths and a funeral: from caspases to alternative mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Tumor necrosis factor alpha induces a caspase-independent death pathway in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Caspase-independent cell death in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Selective inactivation of a Fas-associated death domain protein (FADD)-dependent apoptosis and autophagy pathway in immortal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Synergistic induction of tumor cell apoptosis by death receptor antibody and chemotherapy agent through JNK/p38 and mitochondrial death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Death of HT29 adenocarcinoma cells induced by TNF family receptor activation is caspase-independent and displays features of both apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Lack of p38 MAP kinase activation in TRAIL-resistant cells is not related to the resistance to TRAIL-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

JNK/SAPK activity contributes to TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

c-Jun N-terminal kinase contributes to apoptotic synergy induced by tumor necrosis factor-related apoptosis-inducing ligand plus DNA damage in chemoresistant, p53 inactive mesothelioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M503621200

21 January 2018

Identifiers

DOI

10.1074/JBC.M503621200

1 reference

2 September 2017

1 reference