Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways (Q44009285)

28 November 2017

Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways (English)

1 reference

28 November 2017

Toshiaki Ohtsuka

1

1 reference

PubMed ID

12034736

28 November 2017

Tong Zhou

series ordinal

2

1 reference

PubMed ID

12034736

28 November 2017

language of work or name

English

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publication date

28 May 2002

1 reference

Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

29294-29303

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28 November 2017

32

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Identification and characterization of a new member of the TNF family that induces apoptosis

28 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

The receptor for the cytotoxic ligand TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Activation of the c-Jun N-terminal kinase/stress-activated protein kinase pathway by overexpression of caspase-8 and its homologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Organelle-specific initiation of cell death pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Parallel signal processing among mammalian MAPKs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Methylglyoxal induces apoptosis in Jurkat leukemia T cells by activating c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

Increased expression of death receptors 4 and 5 synergizes the apoptosis response to combined treatment with etoposide and TRAIL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203342200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203342200

1 reference

28 November 2017

1 reference

PubMed ID

12034736