Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies (Q38311787)

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scientific article published on December 2014

Language	Label	Description	Also known as
English	Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies	scientific article published on December 2014

Statements

scholarly article

1 reference

Europe PubMed Central

2 September 2017

1 reference

Europe PubMed Central

Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies (English)

1 reference

Europe PubMed Central

2 September 2017

author name string

N Johns

1

1 reference

Europe PubMed Central

2 September 2017

B H Tan

2

1 reference

Europe PubMed Central

2 September 2017

M MacMillan

3

1 reference

Europe PubMed Central

2 September 2017

T S Solheim

4

1 reference

Europe PubMed Central

2 September 2017

J A Ross

5

1 reference

Europe PubMed Central

2 September 2017

V E Baracos

6

1 reference

Europe PubMed Central

2 September 2017

S Damaraju

7

1 reference

Europe PubMed Central

2 September 2017

K C H Fearon

8

1 reference

Europe PubMed Central

2 September 2017

publication date

1 December 2014

1 reference

Europe PubMed Central

2 September 2017

Journal of Genetics

1 reference

Europe PubMed Central

2 September 2017

93

1 reference

Europe PubMed Central

2 September 2017

893-916

1 reference

Europe PubMed Central

2 September 2017

3

1 reference

Europe PubMed Central

2 September 2017

https://scigraph.springernature.com/pub.10.1007/s12041-014-0405-9

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Clinical significance of serum levels of E-selectin, intercellular adhesion molecule-1, and vascular cell adhesion molecule-1 in gastric cancer patients

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Consensus on cachexia definitions.

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The cachexia score (CASCO): a new tool for staging cachectic cancer patients.

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Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed and secreted by human (SGBS) adipocytes.

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Pitfalls in defining and quantifying cachexia

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A polymorphism of the interleukin-1 beta gene influences survival in pancreatic cancer

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Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia.

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STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia

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Defining and classifying cancer cachexia: a proposal by the SCRINIO Working Group

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Cancer cachexia is associated with the IL10 -1082 gene promoter polymorphism in patients with gastroesophageal malignancy.

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Molecular evidence for a link between the N363S glucocorticoid receptor polymorphism and altered gene expression

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Val103Ile polymorphism of the melanocortin-4 receptor gene (MC4R) in cancer cachexia

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Central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential?

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Chaperoning of glucocorticoid receptors

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Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders.

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Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors

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Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor

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Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study

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Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival

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The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus.

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Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression.

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Mapping the genetic architecture of gene expression in human liver

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Human resistin stimulates the pro-inflammatory cytokines TNF-alpha and IL-12 in macrophages by NF-kappaB-dependent pathway.

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Systemic zinc redistribution and dyshomeostasis in cancer cachexia

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A common functional polymorphism (C-->A substitution at position -863) in the promoter region of the tumour necrosis factor-alpha (TNF-alpha) gene associated with reduced circulating levels of TNF-alpha

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Is there a genetic cause for cancer cachexia? - a clinical validation study in 1797 patients

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Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

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Cachexia, survival and the acute phase response

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A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis

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21 January 2018

Interleukin-10 gene polymorphisms influence susceptibility to cachexia in patients with low-third gastric cancer in a Chinese population.

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21 January 2018

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P-selectin genotype is associated with the development of cancer cachexia

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Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss

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21 January 2018

A single nucleotide polymorphism in NF-κB inducing kinase is associated with mortality in septic shock

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IL18 haplotypes are associated with serum IL-18 concentrations in a population-based study and a cohort of individuals with premature coronary heart disease.

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Cachexia in cancer patients

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21 January 2018

Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice

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Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

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Cooperation of Toll-like receptor signals in innate immune defence

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21 January 2018

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Short-term regulation of glucokinase

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21 January 2018

Common genetic variation in the IGF-1 gene, serum IGF-I levels and breast density.

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21 January 2018

P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study.

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1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Candidate genes for respiratory disease associated with markers of inflammation and endothelial dysfunction in elderly men

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Target SNP selection in complex disease association studies

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Effect of the interleukin-6 (-174) g/c promoter polymorphism on adiponectin and insulin sensitivity.

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

A Variant in the LRRFIP1 Gene Is Associated With Adiposity and Inflammation

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Glucocorticoid receptor gene polymorphisms are associated with reduced first-phase glucose-stimulated insulin secretion and disposition index in women, but not in men

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Excessive fat accumulation is associated with the TNFα -308 G/A promoter polymorphism in women but not in men

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

IL-1B and IL-1RN gene polymorphisms in rheumatoid arthritis: relationship with protein plasma levels and response to therapy

1 reference

https://api.crossref.org/works/10.1007%2FS12041-014-0405-9

21 January 2018

Association of TNF haplotypes with asthma, serum IgE levels, and correlation with serum TNF-alpha levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leptin in the regulation of immunity, inflammation, and hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 (IL6) genotype is associated with fat-free mass in men but not women

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 System Gene Polymorphisms Are Associated with Fat Mass in Young Men

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

10.5-kb homozygote of tumor necrosis factor-beta gene is associated with a better prognosis in gastric cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of interleukin-10 gene polymorphism with cachexia in Chinese patients with gastric cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Host immune gene polymorphisms were associated with the prognosis of non-small-cell lung cancer in Chinese

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resting energy expenditure in patients with newly detected gastric and colorectal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of IL-1beta gene polymorphism with cachexia from locally advanced gastric cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ciliary neurotrophic factor prevents unweighting-induced functional changes in rat soleus muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adiponectin and adiponectin receptor gene variants in relation to resting metabolic rate, respiratory quotient, and adiposity-related phenotypes in the Quebec Family Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between toll-like receptor polymorphisms and serum levels of tumor necrosis factor-alpha and its soluble receptors in obese children.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central ghrelin modulates sympathetic activity in conscious rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3 kinase regulation of skeletal muscle hypertrophy and atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum levels of E-selectin, ICAM-1 and VCAM-1 in colorectal cancer patients: correlations with clinicopathological features, patient survival and tumour surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

rs4215 SNP in zinc-α2-glycoprotein gene is associated with obesity in Chinese north Han population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 genetic polymorphisms and their relationship to the cancer anorexia/weight loss syndrome in metastatic gastric and gastroesophageal junction adenocarcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of lipoprotein lipase S447X stop codon affects the magnitude of interleukin 8 release after cardiac surgery with cardiopulmonary bypass

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucine 7 to proline 7 polymorphism in the neuropeptide Y gene is associated with enhanced carotid atherosclerosis in elderly patients with type 2 diabetes and control subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Leu7Pro polymorphism of neuropeptide Y is associated with younger age of onset of type 2 diabetes mellitus and increased risk for nephropathy in subjects with diabetic retinopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of IL-6 gene polymorphisms with cachexia susceptibility and survival time of patients with pancreatic cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-18 gene polymorphisms affect IL-18 production capability by monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokines in the pathogenesis of cancer cachexia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphism in IL1B: IL1B-511 association with tuberculosis and decreased lipopolysaccharide-induced IL-1beta in IFN-gamma primed ex-vivo whole blood assay.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cox-2 gene polymorphism and IL-6 levels in coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic Role ofInterleukin-1βGene andInterleukin-1 Receptor AntagonistGene Polymorphisms in Patients With Advanced Gastric Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In-vitro secretion of proinflammatory cytokines by human amniochorion carrying hyper-responsive gene polymorphisms of tumour necrosis factor-alpha and interleukin-1beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factors and their binding proteins: biological actions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise training is not associated with improved levels of C-reactive protein or adiponectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A variant in the LRRFIP1 gene is associated with adiposity and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNTF genotype is associated with muscular strength and quality in humans across the adult age span

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the li

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ghrelin-induced food intake is mediated via the orexin pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum levels of interleukin-10 and interleukin-12 in patients with colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The study of tumor necrosis factor beta gene polymorphism in lung cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial uncoupling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between the Thr715Pro P-selectin gene polymorphism and soluble P-selectin levels in a multiethnic population in South London

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiotensin II induces skeletal muscle wasting through enhanced protein degradation and down-regulates autocrine insulin-like growth factor I

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer anorexia-cachexia syndrome: are neuropeptides the key?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of human lipoprotein lipase by carboxy-terminal truncation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25572253

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12041-014-0405-9

1 reference

Europe PubMed Central

2 September 2017

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

2 September 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

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