Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop (Q38296620)

1 September 2017

Purified NPC1 protein: II. Localization of sterol binding to a 240-amino acid soluble luminal loop (English)

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1 September 2017

Arun Radhakrishnan

2

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Nick Grishin

6

object named as

Nick V Grishin

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1 September 2017

7

Joseph L Goldstein

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1 September 2017

Rodney E Infante

1

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1 September 2017

Lina Abi-Mosleh

3

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1 September 2017

Lisa N Kinch

4

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1 September 2017

Michael L Wang

5

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1 September 2017

Michael S Brown

8

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1 September 2017

language of work or name

English

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publication date

6 November 2007

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Journal of Biological Chemistry

1 September 2017

12

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based on heuristic

inferred from page(s)

published in

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1 September 2017

283

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1 September 2017

1064-1075

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1 September 2017

2

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Molecular medicine. The cholesterol quartet

1 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Sphingolipid metabolism diseases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707944200

Niemann-Pick disease type C.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707944200

Cholesterol is sequestered in the brains of mice with Niemann-Pick type C disease but turnover is increased.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Niemann-Pick C research from mouse to gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Protein sensors for membrane sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

A receptor-mediated pathway for cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Sterols regulate processing of carbohydrate chains of wild-type SREBP cleavage-activating protein (SCAP), but not sterol-resistant mutants Y298C or D443N.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Regulated cleavage of sterol regulatory element binding proteins requires sequences on both sides of the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low density lipoprotein cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Identification of HE1 as the second gene of Niemann-Pick C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

NPC1 and NPC2 Regulate Cellular Cholesterol Homeostasis through Generation of Low Density Lipoprotein Cholesterol-derived Oxysterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

A porcine homolog of the major secretory protein of human epididymis, HE1, specifically binds cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Mechanism of cholesterol transfer from the Niemann-Pick type C2 protein to model membranes supports a role in lysosomal cholesterol transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Effect of Detergents on the Association of the Glycophorin A Transmembrane Helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

The NPC1 protein: structure implies function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

NPC2, the protein deficient in Niemann-Pick C2 disease, consists of multiple glycoforms that bind a variety of sterols

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707944200

Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein

21 January 2018

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M707944200

19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M707944200

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M707944200

Protein measurement with the Folin phenol reagent

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M707944200

Identifiers

DOI

10.1074/JBC.M707944200

1 reference

1 September 2017

1 reference