A low abundance pool of nascent p21WAF1/Cip1 is targeted by estrogen to activate cyclin E*Cdk2. (Q38296317)

1 September 2017

A low abundance pool of nascent p21WAF1/Cip1 is targeted by estrogen to activate cyclin E*Cdk2. (English)

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1 September 2017

Prall OW

1

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1 September 2017

Carroll JS

series ordinal

2

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1 September 2017

Sutherland RL

series ordinal

3

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1 September 2017

language of work or name

English

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publication date

1 October 2001

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Journal of Biological Chemistry

1 September 2017

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1 September 2017

276

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1 September 2017

48

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1 September 2017

45433-45442

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Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

1 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Deregulated cyclin E induces chromosome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Principles of CDK regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

TGF-beta1 effects on proliferation of rat intestinal epithelial cells are due to inhibition of cyclin D1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

p21 Disrupts the interaction between cdk2 and the E2F-p130 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Shared role of the pRB-related p130 and p107 proteins in limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Exit from G0 and entry into the cell cycle of cells expressing p21Sdi1 antisense RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Anti-sense oligonucleotide of p21(waf1/cip1) prevents interleukin 4-mediated elevation of p27(kip1) in low grade astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Activity and nature of p21(WAF1) complexes during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Association of human cyclin E with a periodic G1-S phase protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

S-Phase entry upon ectopic expression of G1 cyclin-dependent kinases in the absence of retinoblastoma protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

A Unique Domain of pRb2/p130 Acts as an Inhibitor of Cdk2 Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M104752200

21 January 2018

Identifiers

DOI

10.1074/JBC.M104752200

1 reference

1 September 2017

1 reference