Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins. (Q33887377)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9311992%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins (English)

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6 November 2019

1 reference

4

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6 November 2019

author name string

Alevizopoulos K

series ordinal

1

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6 November 2019

Vlach J

series ordinal

2

1 reference

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6 November 2019

Hennecke S

series ordinal

3

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6 November 2019

publication date

1 September 1997

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6 November 2019

language of work or name

0 references

1 reference

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6 November 2019

volume

16

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6 November 2019

issue

17

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6 November 2019

page(s)

5322-5333

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Cellular Targets for Activation by c-Myc Include the DNA Metabolism Enzyme Thymidine Kinase

6 November 2019

cites work

1 reference

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Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position

5 July 2018

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

5 July 2018

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Cell-cycle regulation of gene expression by transcriptional repression.

5 July 2018

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Cyclin E, a redundant cyclin in breast cancer

5 July 2018

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Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc

5 July 2018

1 reference

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p27KIP1 blocks cyclin E-dependent transactivation of cyclin A gene expression

5 July 2018

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Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

5 July 2018

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E2F-1 but not E2F-4 can overcome p16-induced G1 cell-cycle arrest

5 July 2018

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Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

5 July 2018

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Proteins of the Myc network: essential regulators of cell growth and differentiation.

5 July 2018

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Cdc25 cell-cycle phosphatase as a target of c-myc

5 July 2018

1 reference

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Expression of dominant-negative mutant DP-1 blocks cell cycle progression in G1

5 July 2018

1 reference

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Cell cycle regulation of the murine cyclin E gene depends on an E2F binding site in the promoter.

5 July 2018

1 reference

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E2F and cell proliferation: a world turned upside down

5 July 2018

1 reference

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Regulation of cyclin E transcription by E2Fs and retinoblastoma protein

5 July 2018

1 reference

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

5 July 2018

1 reference

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

5 July 2018

1 reference

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

5 July 2018

1 reference

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Regulation of the cyclin E gene by transcription factor E2F1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Interactions of the p107 and Rb proteins with E2F during the cell proliferation response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Differential modulation of cyclin gene expression by MYC

5 July 2018

1 reference

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The c-myc oncogene in tumor progression.

5 July 2018

1 reference

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An E2F-binding site mediates cell-cycle regulated repression of mouse B-myb transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

DNA tumor virus oncoproteins and retinoblastoma gene mutations share the ability to relieve the cell's requirement for cyclin D1 function in G1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Binding and suppression of the Myc transcriptional activation domain by p107.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

5 July 2018

1 reference

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

5 July 2018

1 reference

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Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

5 July 2018

1 reference

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

5 July 2018

1 reference

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G1 phase progression: cycling on cue

5 July 2018

1 reference

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Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes

5 July 2018

1 reference

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Inhibitors of mammalian G1 cyclin-dependent kinases

5 July 2018

1 reference

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

The retinoblastoma protein and cell cycle control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Cloning and characterization of murine p16INK4a and p15INK4b genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

The transcription factor E2F is required for S phase during Drosophila embryogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21WAF1/CIP1/SDI1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

5 July 2018

1 reference

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

5 July 2018

1 reference

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The MYC protein activates transcription of the alpha-prothymosin gene.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

myc function and regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

E2F-induced S phase requires cyclin E.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170164

Abrogation by c-myc of G1 phase arrest induced by RB protein but not by p53

29 October 2018

1 reference

12 December 2020

Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases

1 reference

12 December 2020

Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members

1 reference

12 December 2020

E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity

1 reference

12 December 2020

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

12 December 2020

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

12 December 2020

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

1 reference

12 December 2020

Activation of c-Myc uncouples DNA replication from activation of G1-cyclin-dependent kinases

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/16.17.5322

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9311992%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9311992%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

9311992

1 reference