Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms (Q38293475)

1 September 2017

Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms (English)

1 reference

1 September 2017

1 reference

6

Tom L Blundell

1 reference

1 September 2017

Sarah J Goodger

1

1 reference

1 September 2017

Christopher J Robinson

2

1 reference

1 September 2017

Kevin J Murphy

3

1 reference

1 September 2017

Nijole Gasiunas

4

1 reference

1 September 2017

Nicholas J Harmer

5

1 reference

1 September 2017

David A Pye

7

1 reference

1 September 2017

John T Gallagher

8

1 reference

1 September 2017

language of work or name

English

0 references

publication date

14 February 2008

1 reference

Journal of Biological Chemistry

1 September 2017

1 reference

1 September 2017

283

1 reference

1 September 2017

19

1 reference

1 September 2017

13001-13008

1 reference

Fibroblast growth factors, their receptors and signaling

1 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Fibroblast growth factors and their inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Angiogenesis in cancer and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

The hemostatic system as a regulator of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Fibroblast growth factor signaling in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Cellular signaling by fibroblast growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Exon III splicing switch of fibroblast growth factor (FGF) receptor-2 and -3 can be induced by FGF-1 or FGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Structure of a heparin-linked biologically active dimer of fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Heparin structure and interactions with basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Differential effects of heparin saccharides on the formation of specific fibroblast growth factor (FGF) and FGF receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Regulation of FGF-1 mitogenic activity by heparan sulfate oligosaccharides is dependent on specific structural features: differential requirements for the modulation of FGF-1 and FGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Multiprotein signalling complexes: regional assembly on heparan sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Interactions between heparan sulfate and proteins: the concept of specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Role of heparan sulfate in fibroblast growth factor signalling: a structural view

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Different affinities of glycosaminoglycan oligosaccharides for monomeric and dimeric interleukin-8: a model for chemokine regulation at inflammatory sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Cooperative dimerization of fibroblast growth factor 1 (FGF1) upon a single heparin saccharide may drive the formation of 2:2:1 FGF1.FGFR2c.heparin ternary complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Specificity studies on the heparin lyases from Flavobacterium heparinum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Recombinant human iduronate-2-sulphatase: correction of mucopolysaccharidosis-type II fibroblasts and characterization of the purified enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

Multimers of the fibroblast growth factor (FGF)-FGF receptor-saccharide complex are formed on long oligomers of heparin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704531200

21 January 2018

Identifiers

DOI

10.1074/JBC.M704531200

1 reference

1 September 2017

1 reference