Management of diffuse intrinsic pontine glioma in children: current and future strategies for improving prognosis (Q38273428)

1 September 2017

1 reference

title

Management of diffuse intrinsic pontine glioma in children: current and future strategies for improving prognosis (English)

1 reference

1 September 2017

main subject

diffuse midline glioma

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Alberto Broniscer

3

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author name string

Erica C Kaye

series ordinal

1

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1 September 2017

Justin N Baker

series ordinal

2

1 reference

1 September 2017

publication date

1 November 2014

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1 September 2017

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1 September 2017

volume

3

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1 September 2017

issue

6

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1 September 2017

page(s)

421-431

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Time to rethink the unthinkable: upfront biopsy of children with newly diagnosed diffuse intrinsic pontine glioma (DIPG).

1 September 2017

cites work

1 reference

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1 October 2018

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Antigen-specific immune responses and clinical outcome after vaccination with glioma-associated antigen peptides and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulose in children with newly diagnosed malignant brainstem

1 October 2018

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Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

1 October 2018

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1 October 2018

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T cells redirected to interleukin-13Rα2 with interleukin-13 mutein--chimeric antigen receptors have anti-glioma activity but also recognize interleukin-13Rα1

1 October 2018

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1 October 2018

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ACVR1 mutations and the genomic landscape of pediatric diffuse glioma.

1 October 2018

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1 October 2018

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Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

1 October 2018

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Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

1 October 2018

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1 October 2018

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1 October 2018

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Results of nimotuzumab and vinorelbine, radiation and re-irradiation for diffuse pontine glioma in childhood.

1 October 2018

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1 October 2018

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A phase I trial of MK-2206 in children with refractory malignancies: a Children's Oncology Group study

1 October 2018

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Hypofractionated conformal radiotherapy for pediatric diffuse intrinsic pontine glioma (DIPG): a randomized controlled trial.

1 October 2018

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Mutation Detection in Activin A Receptor, Type I (ACVR1) Gene in Fibrodysplasia Ossificans Progressiva in An Iranian Family

1 October 2018

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Phase I/II study of erlotinib and temsirolimus for patients with recurrent malignant gliomas: North American Brain Tumor Consortium trial 04-02

1 October 2018

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Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

1 October 2018

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Is biopsy safe in children with newly diagnosed diffuse intrinsic pontine glioma?

1 October 2018

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Best practices for pediatric palliative cancer care: a primer for clinical providers.

1 October 2018

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Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.

1 October 2018

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Inhibition of DNA double-strand break repair by the dual PI3K/mTOR inhibitor NVP-BEZ235 as a strategy for radiosensitization of glioblastoma

1 October 2018

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1 October 2018

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Targeting Wee1 for the treatment of pediatric high-grade gliomas

1 October 2018

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Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes

1 October 2018

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ACVR1 (587T>C) mutation in a variant form of fibrodysplasia ossificans progressiva: second report.

1 October 2018

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1 October 2018

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The somatic genomic landscape of glioblastoma

1 October 2018

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PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma

1 October 2018

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Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas

1 October 2018

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A new class of small molecule inhibitor of BMP signaling

1 October 2018

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The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

1 October 2018

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Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

1 October 2018

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Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma

1 October 2018

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A multi-disciplinary consensus statement concerning surgical approaches to low-grade, high-grade astrocytomas and diffuse intrinsic pontine gliomas in childhood (CPN Paris 2011) using the Delphi method

1 October 2018

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WEE1 kinase inhibition enhances the radiation response of diffuse intrinsic pontine gliomas

1 October 2018

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α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial.

1 October 2018

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CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009.

1 October 2018

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Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

1 October 2018

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Drug delivery strategies for the treatment of malignant gliomas

1 October 2018

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Hypofractionation vs conventional radiation therapy for newly diagnosed diffuse intrinsic pontine glioma: a matched-cohort analysis

1 October 2018

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

1 October 2018

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Sequential immunotherapy by vaccination with GM-CSF-expressing glioma cells and CTLA-4 blockade effectively treats established murine intracranial tumors

1 October 2018

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Peptide-pulsed dendritic cell vaccination targeting interleukin-13 receptor α2 chain in recurrent malignant glioma patients with HLA-A*24/A*02 allele.

1 October 2018

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Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas

1 October 2018

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1 October 2018

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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

1 October 2018

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1 October 2018

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Genomic aberrations in pediatric diffuse intrinsic pontine gliomas

1 October 2018

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Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma

1 October 2018

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1 October 2018

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1 October 2018

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1 October 2018

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1 October 2018

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1 October 2018

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In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma

1 October 2018

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Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

1 October 2018

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1 October 2018

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Palliative care of children with brain tumors: a parental perspective

1 October 2018

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Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets

1 October 2018

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ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors

1 October 2018

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The epidermal growth factor receptor as a therapeutic target in glioblastoma multiforme and other malignant neoplasms

1 October 2018

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Novel drug delivery strategies in neuro-oncology

1 October 2018

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P-glycoprotein and breast cancer resistance protein influence brain distribution of dasatinib

1 October 2018

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The EGFRvIII variant in glioblastoma multiforme

1 October 2018

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Brain accumulation of dasatinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by elacridar treatment

1 October 2018

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1 October 2018

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Classic and atypical fibrodysplasia ossificans progressiva (FOP) phenotypes are caused by mutations in the bone morphogenetic protein (BMP) type I receptor ACVR1

1 October 2018

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1 October 2018

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The role of hypofractionation radiotherapy for diffuse intrinsic brainstem glioma in children: a pilot study

1 October 2018

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Replication-dependent radiosensitization of human glioma cells by inhibition of poly(ADP-Ribose) polymerase: mechanisms and therapeutic potential

1 October 2018

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Phase I study of everolimus in pediatric patients with refractory solid tumors

1 October 2018

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Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology

1 October 2018

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

1 October 2018

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Diffuse brainstem glioma in children: critical review of clinical trials

1 October 2018

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Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft

1 October 2018

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Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

1 October 2018

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Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

1 October 2018

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Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

1 October 2018

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Symptoms and suffering at the end of life in children with cancer

1 October 2018

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Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

1 October 2018

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There is no role for hyperfractionated radiotherapy in the management of children with newly diagnosed diffuse intrinsic brainstem tumors: results of a Pediatric Oncology Group phase III trial comparing conventional vs. hyperfractionated radiotherap

1 October 2018

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Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase

1 October 2018

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UKCCSG study of accelerated radiotherapy for pediatric brain stem gliomas. United Kingdom Childhood Cancer Study Group

1 October 2018

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Radiologic classification of brain stem tumors: correlation of magnetic resonance imaging appearance with clinical outcome

1 October 2018

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Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group study

1 October 2018

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Hyperfractionated radiation therapy (72 Gy) for children with brain stem gliomas. A Childrens Cancer Group Phase I/II Trial

1 October 2018

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Pre-irradiation chemotherapy and hyperfractionated radiation therapy 66 Gy for children with brain stem tumors. A phase II study of the Pediatric Oncology Group, Protocol 8833.

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6113728

Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: a report from the Children's Cancer Group.

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6113728

Results of a pilot study of hyperfractionated radiation therapy for children with brain stem gliomas

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6113728

Brain stem gliomas: a classification system based on magnetic resonance imaging

1 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6113728

1 October 2018

Identifiers

DOI

10.2217/CNS.14.47

1 reference

1 September 2017

0 references

1 reference