The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma (Q33751426)

29 July 2017

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma (English)

1 reference

29 July 2017

diffuse midline glioma

0 references

21

Robert Huether

1 reference

29 July 2017

Jake C Russell

31

0 references

Alberto Broniscer

Alberto Broniscer

37

0 references

Stanley Pounds

Stanley Pounds

18

0 references

John Easton

John Easton

11

0 references

Chris Jones

Chris Jones

35

0 references

Elaine Mardis

41

Elaine R Mardis

1 reference

29 July 2017

23

Matthew Parker

1 reference

29 July 2017

42

Richard K Wilson

1 reference

29 July 2017

34

Lucinda L Fulton

1 reference

29 July 2017

32

Kerri Ochoa

1 reference

29 July 2017

17

Michael Rusch

1 reference

29 July 2017

25

Jared Becksfort

1 reference

29 July 2017

22

Richard Kriwacki

1 reference

29 July 2017

16

Erin Hedlund

1 reference

29 July 2017

28

Kristy Boggs

1 reference

29 July 2017

30

Donald Yergeau

1 reference

29 July 2017

29

Bhavin Vadodaria

1 reference

29 July 2017

27

Heather L Mulder

1 reference

29 July 2017

39

Amar Gajjar

1 reference

29 July 2017

36

Frederick A Boop

1 reference

29 July 2017

12

Michael Edmonson

1 reference

29 July 2017

3

Barbara S Paugh

1 reference

29 July 2017

15

Panduka Nagahawatte

1 reference

29 July 2017

Gang Wu

1

1 reference

29 July 2017

Alexander K Diaz

2

1 reference

29 July 2017

Sherri L Rankin

4

1 reference

29 July 2017

Bensheng Ju

5

1 reference

29 July 2017

Yongjin Li

6

1 reference

29 July 2017

Xiaoyan Zhu

7

1 reference

29 July 2017

Chunxu Qu

8

1 reference

29 July 2017

Xiang Chen

9

1 reference

29 July 2017

Junyuan Zhang

10

1 reference

29 July 2017

Xiaotu Ma

13

1 reference

29 July 2017

Charles Lu

14

1 reference

29 July 2017

Tong Lin

19

1 reference

29 July 2017

Arzu Onar-Thomas

20

1 reference

29 July 2017

Pankaj Gupta

24

1 reference

29 July 2017

Lei Wei

26

1 reference

29 July 2017

Robert S Fulton

33

1 reference

29 July 2017

Cynthia Wetmore

38

1 reference

29 July 2017

Li Ding

40

1 reference

29 July 2017

Michael R Taylor

43

1 reference

29 July 2017

James R Downing

44

1 reference

29 July 2017

David W Ellison

45

1 reference

29 July 2017

Jinghui Zhang

46

1 reference

29 July 2017

Suzanne J Baker

47

1 reference

29 July 2017

language of work or name

English

0 references

publication date

6 April 2014

1 reference

29 July 2017

1 reference

29 July 2017

46

1 reference

29 July 2017

444-450

1 reference

29 July 2017

5

1 reference

describes a project that uses

29 July 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4056452

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ng.2938

0 references

cites work

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

1 reference

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The integrated landscape of driver genomic alterations in glioblastoma

21 June 2018

1 reference

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Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

21 June 2018

1 reference

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Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation

21 June 2018

1 reference

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Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression

21 June 2018

1 reference

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Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

21 June 2018

1 reference

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Constitutively active ALK2 receptor mutants require type II receptor cooperation

21 June 2018

1 reference

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Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

21 June 2018

1 reference

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TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Criteria for inference of chromothripsis in cancer genomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas

21 June 2018

1 reference

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The genomic landscape of hypodiploid acute lymphoblastic leukemia

21 June 2018

1 reference

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Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma.

21 June 2018

1 reference

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c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

21 June 2018

1 reference

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Transcriptional amplification in tumor cells with elevated c-Myc.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva

21 June 2018

1 reference

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Dissecting the genomic complexity underlying medulloblastoma

21 June 2018

1 reference

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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

21 June 2018

1 reference

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Novel mutations target distinct subgroups of medulloblastoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas

21 June 2018

1 reference

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A mouse model of the most aggressive subgroup of human medulloblastoma

21 June 2018

1 reference

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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

21 June 2018

1 reference

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

21 June 2018

1 reference

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

21 June 2018

1 reference

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A novel retinoblastoma therapy from genomic and epigenetic analyses

21 June 2018

1 reference

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Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

CREST maps somatic structural variation in cancer genomes with base-pair resolution.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Histone onco-modifications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Role of altered signal transduction in heterotopic ossification and fibrodysplasia ossificans progressiva

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

A distinct spectrum of copy number aberrations in pediatric high-grade gliomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

On Trk--the TrkB signal transduction pathway is an increasingly important target in cancer biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Fast and accurate short read alignment with Burrows-Wheeler transform

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Chemotherapy for malignant brain tumors of childhood.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

An integrated genomic analysis of human glioblastoma multiforme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

SNPdetector: a software tool for sensitive and accurate SNP detection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Fusion of ETV6 to neurotrophin-3 receptor TRKC in acute myeloid leukemia with t(12;15)(p13;q25).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Consed: a graphical tool for sequence finishing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

A sequence analysis of the genomic regions involved in the rearrangements between TPM3 and NTRK1 genes producing TRK oncogenes in papillary thyroid carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Pten loss causes hypertrophy and increased proliferation of astrocytes in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4056452

Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance

30 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.2938

inferred from DOI database lookup

7 January 2021

based on heuristic

Least Median of Squares Regression

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.2938

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.2938

1 reference

29 July 2017

1 reference

29 July 2017

1 reference