Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability (Q38266781)

1 September 2017

Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability (English)

1 reference

1 September 2017

6

Tasuku Honjo

1 reference

1 September 2017

Afzal Husain

1

1 reference

1 September 2017

Nasim A Begum

2

1 reference

1 September 2017

Takako Taniguchi

3

1 reference

1 September 2017

Hisaaki Taniguchi

4

1 reference

1 September 2017

Maki Kobayashi

5

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1 September 2017

language of work or name

English

0 references

publication date

4 February 2016

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1 September 2017

Nature Communications

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1 September 2017

7

1 reference

1 September 2017

10549

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Creative Commons Attribution 4.0 International

1 September 2017

start time

4 February 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms10549

0 references

cites work

APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination

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Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining

6 September 2017

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Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

6 September 2017

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Human α-l-iduronidase uses its own N -glycan as a substrate-binding and catalytic module

6 September 2017

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Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells

6 September 2017

1 reference

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BAF complexes facilitate decatenation of DNA by topoisomerase IIα

6 September 2017

1 reference

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Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.

6 September 2017

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ATM deficiency results in accumulation of DNA-topoisomerase I covalent intermediates in neural cells

6 September 2017

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Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation

6 September 2017

1 reference

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A rapid and sensitive assay for DNA-protein covalent complexes in living cells

6 September 2017

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Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures

6 September 2017

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The spectrum of SWI/SNF mutations, ubiquitous in human cancers

6 September 2017

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STRING v9.1: protein-protein interaction networks, with increased coverage and integration

6 September 2017

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Chromosome translocation, B cell lymphoma, and activation-induced cytidine deaminase

6 September 2017

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The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation

6 September 2017

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Evolutionary comparison of the mechanism of DNA cleavage with respect to immune diversity and genomic instability

6 September 2017

1 reference

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The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination

6 September 2017

1 reference

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An evolutionary view of the mechanism for immune and genome diversity

6 September 2017

1 reference

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The AID dilemma: infection, or cancer?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Transcription as a source of genome instability

6 September 2017

1 reference

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Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)

6 September 2017

1 reference

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Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes

6 September 2017

1 reference

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Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation

6 September 2017

1 reference

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Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

6 September 2017

1 reference

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Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Topoisomerase 1 and single-strand break repair modulate transcription-induced CAG repeat contraction in human cells

6 September 2017

1 reference

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Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation

6 September 2017

1 reference

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ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes

6 September 2017

1 reference

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Topoisomerase 1 provokes the formation of short deletions in repeated sequences upon high transcription in Saccharomyces cerevisiae

6 September 2017

1 reference

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Role for topoisomerase 1 in transcription-associated mutagenesis in yeast

6 September 2017

1 reference

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Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Nucleosome-interacting proteins regulated by DNA and histone methylation

6 September 2017

1 reference

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Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

The biology of chromatin remodeling complexes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

A simple procedure for effective quenching of trypsin activity and prevention of 18O-labeling back-exchange

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Statistical model to analyze quantitative proteomics data obtained by 18O/16O labeling and linear ion trap mass spectrometry: application to the study of vascular endothelial growth factor-induced angiogenesis in endothelial cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Non-B DNA conformations, mutagenesis and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Topoisomerase I inhibitors: camptothecins and beyond

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Inducible DNA breaks in Ig S regions are dependent on AID and UNG

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Cytoscape: a software environment for integrated models of biomolecular interaction networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

The connection between transcription and genomic instability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Mechanisms of chromosomal translocations in B cell lymphomas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Induction of somatic mutation in a human B cell line in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in flanking regions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Translocations among antibody genes in human cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Increased transcription levels induce higher mutation rates in a hypermutating cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

DNA double-strand breaks and ATM activation by transcription-blocking DNA lesions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

The AID enzyme induces class switch recombination in fibroblasts

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Two levels of protection for the B cell genome during somatic hypermutation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

The novel poly(ADP-Ribose) polymerase inhibitor, AG14361, sensitizes cells to topoisomerase I poisons by increasing the persistence of DNA strand breaks.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Increased negative superhelical density in vivo enhances the genetic instability of triplet repeat sequences.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

The novel human gene aprataxin is directly involved in DNA single-strand-break repair.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4742980

Recombination between immunoglobulin variable region gene segments is enhanced by transcription

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS10549

21 January 2018

Identifiers

DOI

10.1038/NCOMMS10549

1 reference

Dimensions Publication ID

1 September 2017

0 references

0 references

1 reference

1 September 2017

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