The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders (Q38262682)

1 September 2017

The ON:OFF switch, σ1R-HINT1 protein, controls GPCR-NMDA receptor cross-regulation: implications in neurological disorders (English)

1 reference

G protein-coupled receptor

1 September 2017

0 references

author

Andrea Pozo-Rodrigálvarez

object named as

Andrea Pozo-Rodrigálvarez

3

0 references

author name string

María Rodríguez-Muñoz

1

1 reference

1 September 2017

Elsa Cortés-Montero

2

1 reference

1 September 2017

Pilar Sánchez-Blázquez

4

1 reference

1 September 2017

Javier Garzón-Niño

5

1 reference

1 September 2017

language of work or name

English

0 references

publication date

10 October 2015

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1 September 2017

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1 September 2017

6

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1 September 2017

34

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1 September 2017

35458-35477

1 reference

describes a project that uses

1 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4742118/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival

6 September 2017

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Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteins

6 September 2017

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The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

6 September 2017

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6 September 2017

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Prevention and repair of circulatory shock and cerebral ischemia/injury by various agents in experimental heatstroke

6 September 2017

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Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin

6 September 2017

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Targeting dopamine D2 and cannabinoid-1 (CB1) receptors in rat nucleus accumbens

6 September 2017

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Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

6 September 2017

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Neuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and Therapeutics

6 September 2017

1 reference

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Morphine alters the selective association between mu-opioid receptors and specific RGS proteins in mouse periaqueductal gray matter

6 September 2017

1 reference

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Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization

6 September 2017

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Serotonin in pain and analgesia: actions in the periphery

6 September 2017

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

6 September 2017

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Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?

6 September 2017

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Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

6 September 2017

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Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases

6 September 2017

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The neurobiology of slow synaptic transmission

6 September 2017

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Glutaminergic hypothesis of schizophrenia: clinical research studies with ketamine

6 September 2017

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Ischemic cell death in brain neurons

6 September 2017

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The changing landscape of ischaemic brain injury mechanisms.

6 September 2017

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Alternatively spliced isoforms of the NMDARI receptor subunit

6 September 2017

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The mu-opioid receptor and the NMDA receptor associate in PAG neurons: implications in pain control.

6 September 2017

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Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors

14 September 2017

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Regulation of dopamine D1 receptor trafficking and desensitization by oligomerization with glutamate N-methyl-D-aspartate receptors.

14 September 2017

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Pregnenolone can protect the brain from cannabis intoxication

14 September 2017

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Heatstroke-induced cerebral ischemia and neuronal damage. Involvement of cytokines and monoamines

28 September 2017

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HINT1 protein: a new therapeutic target to enhance opioid antinociception and block mechanical allodynia

28 September 2017

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The histidine triad nucleotide binding 1 protein is involved in nicotine reward and physical nicotine withdrawal in mice

23 June 2018

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Potentiation of morphine-induced mechanical antinociception by σ₁ receptor inhibition: role of peripheral σ₁ receptors.

23 June 2018

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Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine

23 June 2018

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Roles of phospholipase Cbeta and NMDA receptor in activity-dependent endocannabinoid release

23 June 2018

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Role of mPKCI, a novel mu-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia

23 June 2018

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Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse

23 June 2018

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mu-Opioid receptors modulate NMDA receptor-mediated responses in nucleus accumbens neurons.

23 June 2018

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Sigma receptors in schizophrenic cerebral cortices

23 June 2018

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The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control

23 June 2018

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The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.

31 August 2018

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Sigma-1 receptor antagonism as opioid adjuvant strategy: enhancement of opioid antinociception without increasing adverse effects.

31 August 2018

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Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate.

31 August 2018

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New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714.

31 August 2018

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GPCRs promote the release of zinc ions mediated by nNOS/NO and the redox transducer RGSZ2 protein.

31 August 2018

1 reference

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The histidine triad nucleotide-binding protein 1 supports mu-opioid receptor-glutamate NMDA receptor cross-regulation

31 August 2018

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Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice.

31 August 2018

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NMDAR-nNOS generated zinc recruits PKCgamma to the HINT1-RGS17 complex bound to the C terminus of Mu-opioid receptors.

31 August 2018

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Supersensitivity to amphetamine in protein kinase-C interacting protein/HINT1 knockout mice.

31 August 2018

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Mu-opioid receptor blockade protects against circulatory shock and cerebral ischemia during heatstroke

31 August 2018

1 reference

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Muscarinic receptor stimulation reduces NMDA responses in CA3 hippocampal pyramidal cells via Ca2+-dependent activation of tyrosine phosphatase.

31 August 2018

1 reference

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Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism.

31 August 2018

1 reference

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Inhibition of protein phosphatase 2B upregulates serine phosphorylation of N-methyl-D-aspartate receptor NR1 subunits in striatal neurons in vivo

31 August 2018

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Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia.

31 August 2018

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Group II metabotropic glutamate receptors enhance NMDA receptor currents via a protein kinase C-dependent mechanism in pyramidal neurones of rat prefrontal cortex

31 August 2018

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Ultrastructural localization of the CB1 cannabinoid receptor in mu-opioid receptor patches of the rat Caudate putamen nucleus.

31 August 2018

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Antibodies to the cloned mu-opioid receptor detect various molecular weight forms in areas of mouse brain

31 August 2018

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Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury

31 August 2018

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12 December 2020

Engineered monomeric human histidine triad nucleotide-binding protein 1 hydrolyzes fluorogenic acyl-adenylate and lysyl-tRNA synthetase-generated lysyl-adenylate

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12 December 2020

Electrophysiologic Analysis of Preemptive Effects of Spinal Opioids on N-methyl-D-aspartate Receptor--mediated Events

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Supportive evidence for the association between the Gln2Pro polymorphism in the SIGMAR1 gene and schizophrenia in the Japanese population: a case-control study and an updated meta-analysis

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Identifiers

DOI

10.18632/ONCOTARGET.6064

1 reference

1 September 2017

1 reference

1 September 2017

1 reference