The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. (Q51750311)

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scientific article published on 31 January 2014

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English	The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases.	scientific article published on 31 January 2014

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scholarly article

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. (English)

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

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cannabinoid receptor

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María Rodríguez-Muñoz

2

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

Javier Burgueno

4

object named as

Javier Burgueño

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

Daniel Zamanillo

5

object named as

Daniel Zamanillo

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

author name string

Pilar Sánchez-Blázquez

1

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

Raquel Herrero-Labrador

3

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

Javier Garzón

6

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

publication date

31 January 2014

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

The International Journal of Neuropsychopharmacology

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

17

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

1943-1955

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

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11 April 2018

http://europepmc.org/abstract/MED/24485144

Phencyclidine animal models of schizophrenia: approaches from abnormality of glutamatergic neurotransmission and neurodevelopment

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Pregnenolone and dehydroepiandrosterone as an adjunctive treatment in schizophrenia and schizoaffective disorder: an 8-week, double-blind, randomized, controlled, 2-center, parallel-group trial

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N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors

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Confirmation that the AKT1 (rs2494732) Genotype Influences the Risk of Psychosis in Cannabis Users

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Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

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Testing hypotheses about the relationship between cannabis use and psychosis

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CB1 cannabinoid receptors and on-demand defense against excitotoxicity

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Cannabinoid receptor stimulation is anti-inflammatory and improves memory in old rats

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Causal association between cannabis and psychosis: examination of the evidence

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Signaling pathways from cannabinoid receptor-1 activation to inhibition of N-methyl-D-aspartic acid mediated calcium influx and neurotoxicity in dorsal root ganglion neurons

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Modulation of NMDA and AMPA-mediated synaptic transmission by CB1 receptors in frontal cortical pyramidal cells

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HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity

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Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor

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Gene expression of metabolic enzymes and a protease inhibitor in the prefrontal cortex are decreased in schizophrenia

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Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice

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Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

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The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia

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Effects of NMDA receptor blockade and nitric oxide synthase inhibition on the acute and chronic actions of delta 9-tetrahydrocannabinol in mice

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Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro

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Correlation of plasma neurosteroid levels to the severity of negative symptoms in male patients with schizophrenia

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NMDA receptors and schizophrenia.

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sigma receptor ligands attenuate N-methyl-D-aspartate cytotoxicity in dopaminergic neurons of mesencephalic slice cultures

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Sigma receptors in schizophrenic cerebral cortices

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Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding

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Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore.

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Cannabinoid receptors couple to NMDA receptors to reduce the production of NO and the mobilization of zinc induced by glutamate.

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Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization

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Glutamate and schizophrenia: phencyclidine, N-methyl-D-aspartate receptors, and dopamine-glutamate interactions

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21 January 2018

Involvement of direct inhibition of NMDA receptors in the effects of sigma-receptor ligands on glutamate neurotoxicity in vitro

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Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance.

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The clinical and therapeutic potentials of dehydroepiandrosterone and pregnenolone in schizophrenia

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Gz mediates the long-lasting desensitization of brain CB1 receptors and is essential for cross-tolerance with morphine

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Differences in blood pregnenolone and dehydroepiandrosterone levels between schizophrenia patients and healthy subjects.

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Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization

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Selective loss of cerebral cortical Sigma, but not PCP binding sites in schizophrenia

1 reference

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7 January 2021

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Supportive evidence for the association between the Gln2Pro polymorphism in the SIGMAR1 gene and schizophrenia in the Japanese population: a case-control study and an updated meta-analysis

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Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity

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Hypoactivity of the spinal cannabinoid system results in NMDA-dependent hyperalgesia.

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10.1017/S1461145714000029

1 reference

Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

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24 November 2022

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Europe PubMed Central

11 April 2018

http://europepmc.org/abstract/MED/24485144

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