Palmitoylation and depalmitoylation defects (Q38236849)

31 August 2017

Palmitoylation and depalmitoylation defects (English)

1 reference

31 August 2017

Thorsten Hornemann

1

1 reference

31 August 2017

5 August 2014

1 reference

Journal of Inherited Metabolic Disease

31 August 2017

1 reference

31 August 2017

38

1 reference

31 August 2017

179-186

1 reference

31 August 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1007/s10545-014-9753-0

31 August 2017

0 references

cites work

Paralemmin-1, a modulator of filopodia induction is required for spine maturation

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Erf2, a novel gene product that affects the localization and palmitoylation of Ras2 in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Lipid rafts, detergent-resistant membranes, and raft targeting signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Loss of function mutation in the palmitoyl-transferase HHAT leads to syndromic 46,XY disorder of sex development by impeding Hedgehog protein palmitoylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Normal huntingtin function: an alternative approach to Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation of membrane proteins (Review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Antisense palmitoyl protein thioesterase 1 (PPT1) treatment inhibits PPT1 activity and increases cell death in LA-N-5 neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation and depalmitoylation dynamics at a glance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

ZDHHC8 single nucleotide polymorphism rs175174 is not associated with psychiatric features of the 22q11 deletion syndrome or schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Protein palmitoylation: a regulator of neuronal development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Synaptic strength regulated by palmitate cycling on PSD-95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Protein palmitoylation in neuronal development and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Identification of PSD-95 palmitoylating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Porcupine-mediated lipid-modification regulates the activity and distribution of Wnt proteins in the chick neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Analysis of ProDH, COMT and ZDHHC8 risk variants does not support individual or interactive effects on schizophrenia susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The fat controller: roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation of the SNAP25 protein family: specificity and regulation by DHHC palmitoyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Disruption ofPPT2in mice causes an unusual lysosomal storage disorder with neurovisceral features

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The neuronal ceroid-lipofuscinoses: from past to present

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Modulation of neuronal protein trafficking and function by palmitoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Neuronal palmitoyl acyl transferases exhibit distinct substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

GAP-43 N-terminal translocation signal targets beta-galactosidase to developing axons in a pan-neuronal transgenic mouse line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

PDZ domain proteins of synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Greasing their way: lipid modifications determine protein association with membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Oral cysteamine bitartrate and N-acetylcysteine for patients with infantile neuronal ceroid lipofuscinosis: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation: policing protein stability and traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Genetic variation in the 22q11 locus and susceptibility to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Deficiency of the INCL protein Ppt1 results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Loss of ZDHHC15 expression in a woman with a balanced translocation t(X;15)(q13.3;cen) and severe mental retardation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation regulates epidermal homeostasis and hair follicle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Protein palmitoylation by a family of DHHC protein S-acyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC-12 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Isolation of a novel gene on 8p21.3-22 whose expression is reduced significantly in human colorectal cancers with liver metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The many ways of Wnt in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Transmembrane topology of the protein palmitoyl transferase Akr1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation of the synaptic vesicle fusion machinery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The DHHC domain: a new highly conserved cysteine-rich motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Mutations in ZDHHC9, which encodes a palmitoyltransferase of NRAS and HRAS, cause X-linked mental retardation associated with a Marfanoid habitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Spatio-temporal segregation of Ras signals: one ship, three anchors, many harbors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Huntington's disease: a clinical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The yeast DHHC cysteine-rich domain protein Akr1p is a palmitoyl transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The intracellular dynamic of protein palmitoylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Fatty acid binding to vesicular stomatitis virus glycoprotein: a new type of post-translational modification of the viral glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Acyl-CoA:lysophospholipid acyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Altered palmitoylation and neuropathological deficits in mice lacking HIP14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

The clinical and genetic features of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Multiple palmitoyltransferases are required for palmitoylation-dependent regulation of large conductance calcium- and voltage-activated potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Lysosomal targeting of palmitoyl-protein thioesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

HTT haplotypes contribute to differences in Huntington disease prevalence between Europe and East Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Wnt proteins are lipid-modified and can act as stem cell growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Testing for genetic association between the ZDHHC8 gene locus and susceptibility to schizophrenia: An integrated analysis of multiple datasets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Gain of 5p15.33 is associated with progression of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoylation of huntingtin by HIP14 is essential for its trafficking and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Depalmitoylation of endothelial nitric-oxide synthase by acyl-protein thioesterase 1 is potentiated by Ca(2+)-calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Protein acyl thioesterases (Review).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Identification of CKAP4/p63 as a major substrate of the palmitoyl acyltransferase DHHC2, a putative tumor suppressor, using a novel proteomics method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits [published erratum appears in Hum Mol Genet 1998 Apr;7(4):765]

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-014-9753-0

Storage of saposins A and D in infantile neuronal ceroid-lipofuscinosis

21 January 2018

1 reference

12 December 2020

Palmitoylation of influenza virus proteins

1 reference

12 December 2020

Association of ZDHHC8 polymorphisms with smooth pursuit eye movement abnormality

1 reference

12 December 2020

Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis

1 reference

12 December 2020

Palmitoylation of ligands, receptors, and intracellular signaling molecules

1 reference

12 December 2020

Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase

1 reference

12 December 2020

Fatty acid acylation of proteins in cultured cells

1 reference

12 December 2020

10.1007/S10545-014-9753-0

Identifiers

DOI

1 reference

PubMed ID

25091425

Dimensions Publication ID

31 August 2017

0 references

1 reference

PubMed ID

25091425