The complement system in systemic lupus erythematosus: an update (Q38213193)

31 August 2017

The complement system in systemic lupus erythematosus: an update (English)

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systemic lupus erythematosus

31 August 2017

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Jonatan Leffler

1

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Anna M. Blom

object named as

Anna M Blom

series ordinal

3

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author name string

Anders A Bengtsson

series ordinal

2

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PubMed ID

24845390

31 August 2017

language of work or name

English

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publication date

20 May 2014

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Annals of the Rheumatic Diseases

31 August 2017

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31 August 2017

73

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31 August 2017

1601-1606

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31 August 2017

9

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Evolution of disease burden over five years in a multicenter inception systemic lupus erythematosus cohort

31 August 2017

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Fc gamma receptor biology and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Role of nucleosomes for induction and glomerular binding of autoantibodies in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Autoantibodies predate the onset of systemic lupus erythematosus in northern Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement: a key system for immune surveillance and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

A revised estimate of twin concordance in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Defining the role of the MHC in autoimmunity: a review and pooled analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement deficiencies and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The proteolytic activation systems of complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement activation and inhibition: a delicate balance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Mechanisms of Disease: the complement system and the pathogenesis of systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The identification of a novel splicing mutation in C1qB in a Japanese family with C1q deficiency: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Molecular basis of hereditary C1q deficiency--revisited: identification of several novel disease-causing mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Functional complement C1q abnormality leads to impaired immune complexes and apoptotic cell clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Evaluation of C1q genomic region in minority racial groups of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

SLE with C1q deficiency treated with fresh frozen plasma: a 10-year experience

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Successful cure of C1q deficiency in human subjects treated with hematopoietic stem cell transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Rheumatological manifestations, organ damage and autoimmunity in hereditary C2 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement components 2 and 7 (C2 and C7) gene polymorphisms are not major risk factors for SLE susceptibility in the Malaysian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Deletion variants of RABGAP1L, 10q21.3, and C4 are associated with the risk of systemic lupus erythematosus in Korean women

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Gene copy-number variation and associated polymorphisms of complement component C4 in human systemic lupus erythematosus (SLE): low copy number is a risk factor for and high copy number is a protective factor against SLE susceptibility in European A

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Expression and significance of leukocyte membrane cofactor protein transcript in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Diminished expression of complement regulatory proteins on peripheral blood cells from systemic lupus erythematosus patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Deletion of decay-accelerating factor (CD55) exacerbates autoimmune disease development in MRL/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The variant of CD11b, rs1143679 within ITGAM, is associated with systemic lupus erythematosus and clinical manifestations in Brazilian patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

A systemic lupus erythematosus-associated R77H substitution in the CD11b chain of the Mac-1 integrin compromises leukocyte adhesion and phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Multiple lupus-associated ITGAM variants alter Mac-1 functions on neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement receptor 3 influences toll-like receptor 7/8-dependent inflammation: implications for autoimmune diseases characterized by antibody reactivity to ribonucleoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Autoantibodies to complement components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Antibodies against C1q in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Anti-DNA antibodies cross-react with C1q

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Anti-C1q autoantibodies, novel tests, and clinical consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

IgG autoantibodies against deposited C3 inhibit macrophage-mediated apoptotic cell engulfment in systemic autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Macrophages and neutrophils in SLE-An online molecular catalog

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement and non-complement activating functions of C1q: a prototypical innate immune molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Human complement Factor H modulates C1q-mediated phagocytosis of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Annexin A2 and A5 serve as new ligands for C1q on apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

A protective role for innate immunity in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement receptor 2, natural antibodies and innate immunity: Inter-relationships in B cell selection and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Transcriptional effects of a lupus-associated polymorphism in the 5' untranslated region (UTR) of human complement receptor 2 (CR2/CD21)

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Human complement receptor 2 (CR2/CD21) as a receptor for DNA: implications for its roles in the immune response and the pathogenesis of systemic lupus erythematosus (SLE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Expression and role of CR1 and CR2 on B and T lymphocytes under physiological and autoimmune conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

T-cell stimulation and regulation: with complements from CD46.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Plasmacytoid dendritic cells and C1q differentially regulate inflammatory gene induction by lupus immune complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

C1q limits dendritic cell differentiation and activation by engaging LAIR-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Macrophage clearance of neutrophil extracellular traps is a silent process

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Lupus neutrophils: 'NET' gain in understanding lupus pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Defective complement inhibitory function predisposes to renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Immune complex processing in patients with systemic lupus erythematosus. In vivo imaging and clearance studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Thrombosis in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Risk of pulmonary embolism in patients with autoimmune disorders: a nationwide follow-up study from Sweden

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Complement system and small HDL particles are associated with subclinical atherosclerosis in SLE patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus--a possible link to venous thrombosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

The role of complement in the antiphospholipid syndrome: a novel mechanism for pregnancy morbidity

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Measurement of cell-bound complement activation products enhances diagnostic performance in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Amelioration of lupus-like autoimmune disease in NZB/WF1 mice after treatment with a blocking monoclonal antibody specific for complement component C5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Targeting the complement system in systemic lupus erythematosus and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Atypical hemolytic uremic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Eculizumab for the Treatment of Dense-Deposit Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

Diagnostic value of serum anti-C1q antibodies in patients with lupus nephritis: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FANNRHEUMDIS-2014-205287

10.1136/ANNRHEUMDIS-2014-205287

21 January 2018

Identifiers

DOI

1 reference

31 August 2017

1 reference

PubMed ID

24845390