Complement and non-complement activating functions of C1q: a prototypical innate immune molecule (Q37859539)

24 August 2017

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title

Complement and non-complement activating functions of C1q: a prototypical innate immune molecule (English)

1 reference

24 August 2017

Annapurna Nayak

1

1 reference

24 August 2017

Lina Pednekar

series ordinal

2

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24 August 2017

Kenneth B M Reid

series ordinal

3

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24 August 2017

Uday Kishore

series ordinal

4

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24 August 2017

30 March 2011

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24 August 2017

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24 August 2017

18

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24 August 2017

2

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24 August 2017

350-363

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Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q

24 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Subunit composition and structure of subcomponent C1q of the first component of human complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q: structure, function, and receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Modular organization of proteins containing C1q-like globular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Structural and functional anatomy of the globular domain of complement protein C1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Interaction of human C1q with IgG and IgM: revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Mini-review: A pivotal role for innate immunity in the clearance of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Complement activation by apoptotic cells occurs predominantly via IgM and is limited to late apoptotic (secondary necrotic) cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Cartilage proteoglycans: structure and potential functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C-reactive protein and the risk of incident colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Studies on the interactions between C-reactive protein and complement proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Complement protein C1q recognizes enzymatically modified low-density lipoprotein through unesterified fatty acids generated by cholesterol esterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Classical pathway complement activation on human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Blood platelets activate the classical pathway of human complement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Serum complement activation on heterologous platelets is associated with arterial thrombosis in patients with systemic lupus erythematosus and antiphospholipid antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Interaction of the globular domain of human C1q with Salmonella typhimurium lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Low-molecular-weight heparin inhibition in classical complement activation pathway during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The non-classical functions of the classical complement pathway recognition subcomponent C1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Role of complement in neurodegeneration and neuroinflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The classical complement cascade mediates CNS synapse elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Defective B cell tolerance checkpoints in systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Fibronectin binding to complement subcomponent C1q. Localization of their respective binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Human leukocyte C1q receptor binds other soluble proteins with collagen domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The contribution of gC1qR/p33 in infection and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

By Binding SIRPα or Calreticulin/CD91, Lung Collectins Act as Dual Function Surveillance Molecules to Suppress or Enhance Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Primate erythrocyte-immune complex-clearing mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Expression of the CR1 receptor on human leukemia-derived CD4+ T cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Identification of the membrane glycoprotein that is the C3b receptor of the human erythrocyte, polymorphonuclear leukocyte, B lymphocyte, and monocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Direct interaction between CD91 and C1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q and tumor necrosis factor superfamily: modularity and versatility

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q and its growing family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The complete complement of C1q-domain-containing proteins in Homo sapiens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Androgens decrease plasma adiponectin, an insulin-sensitizing adipocyte-derived protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Identification and characterization of nCLP2, a novel C1q family protein expressed in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Cbln1 is essential for synaptic integrity and plasticity in the cerebellum

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

A novel C1q family member with fucose-binding activity from surfperch, Neoditrema ransonnetii (Perciformes, Embiotocidae).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Adipose tissue as an immunological organ: Toll-like receptors, C1q/TNFs and CTRPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

A novel adipokine CTRP1 stimulates aldosterone production

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

CTRP3/cartducin promotes proliferation and migration of endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Effects of the new C1q/TNF-related protein (CTRP-3) "cartonectin" on the adipocytic secretion of adipokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

CTRP3/cartducin is induced by transforming growth factor-beta1 and promotes vascular smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Origin of the classical complement pathway: Lamprey orthologue of mammalian C1q acts as a lectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The C1q domain containing proteins: Where do they come from and what do they do?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

A novel C1q family member of amphioxus was revealed to have a partial function of vertebrate C1q molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Complement system of bony and cartilaginous fish

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Recent advances on the complement system of teleost fish.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Characterization of C1q in teleosts: insight into the molecular and functional evolution of C1q family and classical pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Adiponectin binds C1q and activates the classical pathway of complement

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Beta-amyloid fibrils activate the C1 complex of complement under physiological conditions: evidence for a binding site for A beta on the C1q globular regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Multivalent binding of complement protein C1Q to the amyloid beta-peptide (A beta) promotes the nucleation phase of A beta aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Platelet activation by C1q results in the induction of alpha IIb/beta 3 integrins (GPIIb-IIIa) and the expression of P-selectin and procoagulant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The tissue pentraxin PTX3 limits C1q-mediated complement activation and phagocytosis of apoptotic cells by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Pattern recognition by pentraxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

T cell-dependent immune response in C1q-deficient mice: defective interferon gamma production by antigen-specific T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

C1q enhances IFN-gamma production by antigen-specific T cells via the CD40 costimulatory pathway on dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

Complement C1q reduces early atherosclerosis in low-density lipoprotein receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

A Novel Role of Complement Factor C1q in Augmenting the Presentation of Antigen Captured in Immune Complexes to CD8+ T Lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

The binding site for C1q on IgG

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1753425910396252

21 January 2018

Identifiers

DOI

10.1177/1753425910396252

1 reference

24 August 2017

1 reference