Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics. (Q38202164)

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13 March 2020

title

Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics (English)

1 reference

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13 March 2020

1 reference

1

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13 March 2020

Tetsuya Terasaki

series ordinal

6

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13 March 2020

3

Shingo Ito

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13 March 2020

4

Yasuo Uchida

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13 March 2020

author name string

Mio Hirayama

series ordinal

2

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13 March 2020

Masanori Tachikawa

series ordinal

5

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13 March 2020

publication date

4 April 2014

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Expert Review of Proteomics

13 March 2020

published in

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13 March 2020

volume

11

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13 March 2020

page(s)

303-313

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13 March 2020

issue

3

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Can the pharmaceutical industry reduce attrition rates?

13 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

The blood-brain barrier: bottleneck in brain drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Drug targeting to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Creatine and guanidinoacetate transport at blood-brain and blood-cerebrospinal fluid barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

GLUT1 deficiency syndrome 2013: current state of the art

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Quantitative targeted absolute proteomics-based ADME research as a new path to drug discovery and development: methodology, advantages, strategy, and prospects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood-brain barrier in ddY, FV

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

A one-step procedure for isolation of poly(A)+ mRNA from isolated brain capillaries and endothelial cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Simultaneous absolute protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases as a novel approach for the characterization of individual human liver: comparison with mRNA levels and activities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Quantitative atlas of blood-brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Brain taurine content as a function of cerebral metabolic rate: osmotic regulation of glucose derived water production

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

The facilitative glucose transporter GLUT3: 20 years of distinction

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Characterization and modulation of glucose uptake in a human blood-brain barrier model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

The 4F2hc/LAT1 complex transports L-DOPA across the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Reduced brain 5-HT and elevated NE turnover and metabolites in bipolar affective disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Effects of ketamine on dopamine metabolism during anesthesia in discrete brain regions in mice: comparison with the effects during the recovery and subanesthetic phases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Transport of metabolic substrates through the blood-brain barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Modelling of the blood-brain barrier in drug discovery and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Permeability studies on in vitro blood-brain barrier models: physiology, pathology, and pharmacology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector angiopep-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Blood-brain barrier transport of therapeutics via receptor-mediation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Method for isolation and molecular characterization of extracellular microvesicles released from brain endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

TNAP and EHD1 are over-expressed in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

The proteome of mouse brain microvessel membranes and basal lamina

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Glial-cell-mediated re-induction of the blood-brain barrier phenotype in brain capillary endothelial cells: a differential gel electrophoresis study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Novel effects of edaravone on human brain microvascular endothelial cells revealed by a proteomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Proteomic temporal profile of human brain endothelium after oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Proteomic analysis of human cerebral endothelial cells activated by glutamate/MK-801: significance in ischemic stroke injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Actin, gelsolin and filamin-A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Protein markers of ischemic insult in brain endothelial cells identified using 2D gel electrophoresis and ICAT-based quantitative proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Vascular endothelium-selective gene induction by Tie2 promoter/enhancer in the brain and retina of a transgenic rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

Drug transport across the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830

A Synthetic Protein Approach toward Accurate Mass Spectrometric Quantification of Component Stoichiometry of Multiprotein Complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14789450.2014.893830