Creatine and guanidinoacetate transport at blood-brain and blood-cerebrospinal fluid barriers (Q37976595)

26 August 2017

Creatine and guanidinoacetate transport at blood-brain and blood-cerebrospinal fluid barriers (English)

1 reference

26 August 2017

0 references

1 reference

ChEBI release 2020-05-28

Olivier Braissant

1

1 reference

26 August 2017

18 January 2012

1 reference

Journal of Inherited Metabolic Disease

26 August 2017

1 reference

26 August 2017

35

1 reference

26 August 2017

4

1 reference

26 August 2017

655-664

1 reference

https://scigraph.springernature.com/pub.10.1007/s10545-011-9433-2

26 August 2017

0 references

cites work

Creatine transporter localization in developing and adult retina: importance of creatine to retinal function

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Neuroprotection of creatine supplementation in neonatal rats with transient cerebral hypoxia-ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine and guanidinoacetate: diagnostic markers for inborn errors in creatine biosynthesis and transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Exocytotic release of creatine in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Ammonia toxicity to the brain and creatine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine depletion in a new case with AGAT deficiency: clinical and genetic study in a large pedigree

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Arginine:glycine amidinotransferase (AGAT) deficiency in a newborn: early treatment can prevent phenotypic expression of the disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Synthesis and transport of creatine in the CNS: importance for cerebral functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

X-linked creatine deficiency syndrome: a novel mutation in creatine transporter gene SLC6A8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Swelling-activated taurine and creatine effluxes from rat cortical astrocytes are pharmacologically distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Ammonia toxicity to the brain: effects on creatine metabolism and transport and protective roles of creatine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Current concepts in the pathogenesis of urea cycle disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

AGAT, GAMT and SLC6A8 distribution in the central nervous system, in relation to creatine deficiency syndromes: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

L-arginine uptake, the citrulline-NO cycle and arginase II in the rat brain: an in situ hybridization study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Differential expression of the cationic amino acid transporter 2(B) in the adult rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Endogenous synthesis and transport of creatine in the rat brain: an in situ hybridization study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine synthesis and transport during rat embryogenesis: spatiotemporal expression of AGAT, GAMT and CT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Ammonium alters creatine transport and synthesis in a 3D culture of developing brain cells, resulting in secondary cerebral creatine deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Dissociation of AGAT, GAMT and SLC6A8 in CNS: relevance to creatine deficiency syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine deficiency syndromes and the importance of creatine synthesis in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine: endogenous metabolite, dietary, and therapeutic supplement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatinyl amino acids: new hybrid compounds with neuroprotective activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Hyperammonemia-induced toxicity for the developing central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Looking at the blood-brain barrier: molecular anatomy and possible investigation approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Irreversible brain creatine deficiency with elevated serum and urine creatine: a creatine transporter defect?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Magnetic resonance spectroscopy in a 9-day-old heterozygous female child with creatine transporter deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Treatment with L-arginine improves neuropsychological disorders in a child with creatine transporter defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Congenital creatine transporter deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

1H MR spectroscopy as a diagnostic tool for cerebral creatine deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Guanidinoacetate methyltransferase deficiency: differences of creatine uptake in human brain and muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Arginine supplementation in four patients with X-linked creatine transporter defect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Response to creatine analogs in fibroblasts and patients with creatine transporter deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Guanidinoacetate methyltransferase deficiency: new clinical features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Non-enzymatic cyclization of creatine ethyl ester to creatinine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

In situ hybridization analysis of CHOT1, a creatine transporter, in the rat central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Protective effects of oral creatine supplementation on spinal cord injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Maternal creatine: does it reach the fetus and improve survival after an acute hypoxic episode in the spiny mouse (Acomys cahirinus)?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Developmental changes in the expression of creatine synthesizing enzymes and creatine transporter in a precocial rodent, the spiny mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

A maternal diet supplemented with creatine from mid-pregnancy protects the newborn spiny mouse brain from birth hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Arginine:glycine amidinotransferase deficiency: the third inborn error of creatine metabolism in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine uptake in brain and skeletal muscle of mice lacking guanidinoacetate methyltransferase assessed by magnetic resonance spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Intracerebroventricular administration of creatine protects against damage by global cerebral ischemia in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Immunohistochemical localisation of the creatine transporter in the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Two novel mutations in SLC6A8 cause creatine transporter defect and distinctive X-linked mental retardation in two unrelated Dutch families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Evidence for creatine biosynthesis in Müller glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Engaging neuroscience to advance translational research in brain barrier biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The blood-brain barrier creatine transporter is a major pathway for supplying creatine to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Kinetics of creatine in blood and brain after intraperitoneal injection in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Protective effects of some creatine derivatives in brain tissue anoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

In vivo neuroprotection by a creatine-derived compound: phosphocreatine-Mg-complex acetate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

X-Linked creatine transporter deficiency in two patients with severe mental retardation and autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

X-linked creatine-transporter gene (SLC6A8) defect: a new creatine-deficiency syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The putative rat choline transporter CHOT1 transports creatine and is highly expressed in neural and muscle-rich tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Severely altered guanidino compound levels, disturbed body weight homeostasis and impaired fertility in a mouse model of guanidinoacetate N-methyltransferase (GAMT) deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine deficiency syndrome caused by guanidinoacetate methyltransferase deficiency: diagnostic tools for a new inborn error of metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Lack of creatine in muscle and brain in an adult with GAMT deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Presymptomatic treatment of neonatal guanidinoacetate methyltransferase deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

1H MR spectroscopy of the brain in Cr transporter defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Nature and consequences of mammalian brain and CSF efflux transporters: four decades of progress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine replacement therapy in guanidinoacetate methyltransferase deficiency, a novel inborn error of metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Transport characteristics of guanidino compounds at the blood-brain barrier and blood-cerebrospinal fluid barrier: relevance to neural disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK-Mi and CK-B suggest a novel neuron-glial relationship for brain energy homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Expression and possible role of creatine transporter in the brain and at the blood-cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Evolutionary evidence of the effect of rare variants on disease etiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Spatiotemporal expression of the creatine metabolism related genes agat, gamt and ct1 during zebrafish embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Choroid plexus: biology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Astrocyte heterogeneity: an underappreciated topic in neurobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Materno-fetal transport of creatine in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

Creatine deficiency in the brain: a new, treatable inborn error of metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10545-011-9433-2

The neuroprotective role of creatine.

21 January 2018

1 reference

12 December 2020

Dietary supplement creatine protects against traumatic brain injury

1 reference

12 December 2020

Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans.

1 reference

12 December 2020

The Blood–Brain Barrier Creatine Transporter is a Major Pathway for Supplying Creatine to the Brain

1 reference

12 December 2020

Therapeutic trial of arginine restriction in creatine deficiency syndrome

1 reference

12 December 2020

Creatine and creatinine metabolism

1 reference

12 December 2020

Ammonium-induced impairment of axonal growth is prevented through glial creatine.

1 reference

12 December 2020

Pre-symptomatic treatment of creatine biosynthesis defects

1 reference

12 December 2020

Clinical features and X-inactivation in females heterozygous for creatine transporter defect.

1 reference

12 December 2020

Increase of total creatine in human brain after oral supplementation of creatine-monohydrate.

1 reference

12 December 2020

Expression and function of AGAT, GAMT and CT1 in the mammalian brain

1 reference

12 December 2020

Treatment by oral creatine, L-arginine and L-glycine in six severely affected patients with creatine transporter defect.

1 reference

12 December 2020

Searching for a therapy of creatine transporter deficiency: some effects of creatine ethyl ester in brain slices in vitro.

1 reference

12 December 2020

Long-term follow-up and treatment in nine boys with X-linked creatine transporter defect

1 reference

12 December 2020

Cerebral creatine deficiency syndromes: clinical aspects, treatment and pathophysiology.

1 reference

12 December 2020

10.1007/S10545-011-9433-2

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22252611