Ubiquitin in inflammation: the right linkage makes all the difference (Q38201969)

30 August 2017

Ubiquitin in inflammation: the right linkage makes all the difference (English)

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30 August 2017

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30 August 2017

Domagoj Vucic

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30 August 2017

1 April 2014

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Nature Structural & Molecular Biology

30 August 2017

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30 August 2017

21

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30 August 2017

4

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30 August 2017

297-300

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https://scigraph.springernature.com/pub.10.1038/nsmb.2808

30 August 2017

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Polyubiquitin chains: polymeric protein signals

21 January 2018

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Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review series

21 January 2018

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Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

21 January 2018

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Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

21 January 2018

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Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions

21 January 2018

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RING domain E3 ubiquitin ligases

21 January 2018

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Ubiquitin in the immune system

21 January 2018

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

21 January 2018

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c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

21 January 2018

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Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors

21 January 2018

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c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

21 January 2018

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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

21 January 2018

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SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

21 January 2018

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Linear ubiquitination prevents inflammation and regulates immune signalling

21 January 2018

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

21 January 2018

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The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

21 January 2018

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OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

21 January 2018

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The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

21 January 2018

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Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

21 January 2018

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

21 January 2018

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Regulation of IkappaB kinase-related kinases and antiviral responses by tumor suppressor CYLD.

21 January 2018

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Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction

21 January 2018

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

21 January 2018

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Structural properties of polyubiquitin chains in solution

21 January 2018

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Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

21 January 2018

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E2 interaction and dimerization in the crystal structure of TRAF6

21 January 2018

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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2

21 January 2018

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Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

21 January 2018

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The structure of the CYLD USP domain explains its specificity for Lys63-linked polyubiquitin and reveals a B box module

21 January 2018

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A ubiquitin ligase complex assembles linear polyubiquitin chains

21 January 2018

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UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

21 January 2018

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Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP

21 January 2018

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Compact Parkin only: insights into the structure of an autoinhibited ubiquitin ligase

21 January 2018

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The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

21 January 2018

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The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

21 January 2018

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31 March 2020

Identifiers

DOI

10.1038/NSMB.2808

1 reference

30 August 2017

1 reference

PubMed ID

24699077