Diverse roles of C-terminal Hsp70-interacting protein (CHIP) in tumorigenesis (Q38173991)

30 August 2017

Diverse roles of C-terminal Hsp70-interacting protein (CHIP) in tumorigenesis (English)

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30 August 2017

Chao Sun

1

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30 August 2017

Hai-Long Li

2

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30 August 2017

Mei-Lin Shi

3

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30 August 2017

Qing-Hua Liu

4

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30 August 2017

Jin Bai

5

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30 August 2017

Jun-Nian Zheng

6

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30 August 2017

27 December 2013

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Journal of Cancer Research and Clinical Oncology

30 August 2017

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30 August 2017

140

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30 August 2017

189-197

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30 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00432-013-1571-5

30 August 2017

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The U box is a modified RING finger — a common domain in ubiquitination

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Predictors of long-term survival in patients with gallbladder cancer

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Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

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Series introduction: the transcription factor NF-kappaB and human disease

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

21 January 2018

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Ubiquitin signalling in the NF-kappaB pathway

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

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CHIP activates HSF1 and confers protection against apoptosis and cellular stress

21 January 2018

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Brain CHIP: removing the culprits in neurodegenerative disease

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Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 January 2018

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The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation

21 January 2018

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CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha

21 January 2018

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Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation

21 January 2018

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Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents

21 January 2018

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Benefit of adjuvant chemotherapy for resectable gastric cancer: a meta-analysis

21 January 2018

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Stress-induced decrease in TRAF2 stability is mediated by Siah2

21 January 2018

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Shared principles in NF-kappaB signaling

21 January 2018

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c-erbB-2 in breast cancer: development of a clinically useful marker

21 January 2018

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NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression

21 January 2018

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Tid1, CHIP and ErbB2 interactions and their prognostic implications for breast cancer patients.

21 January 2018

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Ubiquitin ligase CHIP induces TRAF2 proteasomal degradation and NF-κB inactivation to regulate breast cancer cell invasion

21 January 2018

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21 January 2018

Cancer statistics, 2007

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21 January 2018

Global cancer statistics

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Quercetin-induced ubiquitination and down-regulation of Her-2/neu

21 January 2018

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Histone deacetylase inhibitors in cancer therapy: is transcription the primary target?

21 January 2018

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The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways.

21 January 2018

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Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC.

21 January 2018

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Nuclear factor-kappaB in cancer development and progression

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

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CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

21 January 2018

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CHIP promotes human telomerase reverse transcriptase degradation and negatively regulates telomerase activity

21 January 2018

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Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation

21 January 2018

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CHIP promotes Runx2 degradation and negatively regulates osteoblast differentiation

21 January 2018

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C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.

21 January 2018

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Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha

21 January 2018

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Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

21 January 2018

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The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

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Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

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CHIP deletion reveals functional redundancy of E3 ligases in promoting degradation of both signaling proteins and expanded glutamine proteins

21 January 2018

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Chaperone-dependent stabilization and degradation of p53 mutants

21 January 2018

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Promotion of CHIP-mediated p53 degradation protects the heart from ischemic injury

21 January 2018

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Docking-dependent ubiquitination of the interferon regulatory factor-1 tumor suppressor protein by the ubiquitin ligase CHIP

21 January 2018

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Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65

21 January 2018

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Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme

21 January 2018

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Ubiquitin and breast cancer

21 January 2018

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Atypical cancer pattern in patients with Parkinson's disease.

21 January 2018

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NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

21 January 2018

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Global cancer statistics, 2002

21 January 2018

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Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer

21 January 2018

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Ubiquitin enters the new millennium

21 January 2018

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A combination of Trastuzumab and 17-AAG induces enhanced ubiquitinylation and lysosomal pathway-dependent ErbB2 degradation and cytotoxicity in ErbB2-overexpressing breast cancer cells

21 January 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

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Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

CHIP functions an E3 ubiquitin ligase of Runx1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Novel targeted therapies in the treatment of gastric and esophageal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

NF-kappaB: a key role in inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Bag1 directly routes immature BCR-ABL for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Malignant gliomas in adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Metastatic lymph node CHIP expression is a potential prognostic marker for resected esophageal squamous cell carcinoma patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Carboxyl terminus of Hsp70-interacting protein (CHIP) contributes to human glioma oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Histone deacetylase inhibitor SAHA induces ERalpha degradation in breast cancer MCF-7 cells by CHIP-mediated ubiquitin pathway and inhibits survival signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

ErbB2 degradation mediated by the co-chaperone protein CHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00432-013-1571-5

Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer

21 January 2018

1 reference

12 December 2020

Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2.

1 reference

12 December 2020

HER2 status and benefit from adjuvant trastuzumab in breast cancer

1 reference

12 December 2020

Mortality and cancer incidence in patients with Parkinson's disease

1 reference

12 December 2020

Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases

1 reference

12 December 2020

Quantitative analysis of breast cancer tissue microarrays shows that both high and normal levels of HER2 expression are associated with poor outcome

1 reference

12 December 2020

Decreased expression of the carboxyl terminus of heat shock cognate 70 interacting protein in human gastric cancer and its clinical significance

1 reference

12 December 2020

Steroid receptor interactions with heat shock protein and immunophilin chaperones

1 reference

12 December 2020

[Analysis of prognostic factors after curative resection for gallbladder carcinoma]

1 reference

12 December 2020

Expression of carboxyl terminus of Hsp70-interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma

1 reference

12 December 2020

Androgen receptor degradation by the E3 ligase CHIP modulates mitotic arrest in prostate cancer cells

1 reference

12 December 2020

Image analysis of androgen receptor immunostaining in prostate cancer accurately predicts response to hormonal therapy

1 reference

12 December 2020

Treatment options in androgen-independent prostate cancer

1 reference

12 December 2020

Molecular chaperones and the art of recognizing a lost cause

1 reference

12 December 2020

Histone deacetylase inhibitors

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12 December 2020

Hormone-refractory breast cancer remains sensitive to the antitumor activity of heat shock protein 90 inhibitors.

1 reference

12 December 2020

CyclinD1, p53, E-cadherin, and VEGF discordant expression in paired regional metastatic lymph nodes of esophageal squamous cell carcinoma: a tissue array analysis

1 reference

12 December 2020

L1 cell adhesion molecule as a novel independent poor prognostic factor in gallbladder carcinoma

1 reference

12 December 2020

Tumours and tremors: how PTEN regulation underlies both

1 reference

12 December 2020

Histone deacetylase inhibitor LAQ824 down-regulates Her-2 and sensitizes human breast cancer cells to trastuzumab, taxotere, gemcitabine, and epothilone B

1 reference

12 December 2020

Depletion of the erbB-2 gene product p185 by benzoquinoid ansamycins

1 reference

12 December 2020

The C-terminus of Hsp70-interacting protein promotes Met receptor degradation.

1 reference

12 December 2020

Destabilization of steroid receptors by heat shock protein 90-binding drugs: a ligand-independent approach to hormonal therapy of breast cancer

1 reference

12 December 2020

10.1007/S00432-013-1571-5

Identifiers

DOI

1 reference

30 August 2017

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