P16INK4A as a surrogate biomarker for human papillomavirus-associated oropharyngeal carcinoma: consideration of some aspects (Q38171835)

30 August 2017

P16INK4A as a surrogate biomarker for human papillomavirus-associated oropharyngeal carcinoma: consideration of some aspects (English)

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30 August 2017

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Hongzhi Wang

1

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30 August 2017

Rui Sun

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2

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30 August 2017

Hui Lin

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3

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30 August 2017

Wei-Han Hu

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4

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30 August 2017

8 November 2013

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30 August 2017

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30 August 2017

104

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30 August 2017

12

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30 August 2017

1553-1559

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p16(INK4a) overexpression predicts translational active human papillomavirus infection in tonsillar cancer

30 August 2017

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12 December 2020

Biological and clinical relevance of transcriptionally active human papillomavirus (HPV) infection in oropharynx squamous cell carcinoma

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12 December 2020

Human papillomavirus and survival of patients with oropharyngeal cancer.

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12 December 2020

Transoral robotic surgery and human papillomavirus status: Oncologic results

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12 December 2020

Effect of HPV-associated p16INK4A expression on response to radiotherapy and survival in squamous cell carcinoma of the head and neck.

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12 December 2020

Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

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12 December 2020

Comparative prognostic value of HPV16 E6 mRNA compared with in situ hybridization for human oropharyngeal squamous carcinoma.

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12 December 2020

Management of human papillomavirus-positive and human papillomavirus-negative head and neck cancer

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12 December 2020

Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review

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12 December 2020

Cellular senescence and tumor suppressor gene p16

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12 December 2020

Prognostic significance of p16INK4A and human papillomavirus in patients with oropharyngeal cancer treated on TROG 02.02 phase III trial

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12 December 2020

Benefit of chemotherapy as part of treatment for HPV DNA-positive but p16-negative squamous cell carcinoma of the oropharynx

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12 December 2020

Human papillomavirus type 16 E6 and E7 oncogenes abrogate radiation-induced DNA damage responses in vivo through p53-dependent and p53-independent pathways

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12 December 2020

A novel RT-PCR method for quantification of human papillomavirus transcripts in archived tissues and its application in oropharyngeal cancer prognosis

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12 December 2020

HPV involvement in tonsillar cancer: prognostic significance and clinically relevant markers

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12 December 2020

Identification of oropharyngeal squamous cell carcinomas with active HPV16 involvement by immunohistochemical analysis of the retinoblastoma protein pathway

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12 December 2020

Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer

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12 December 2020

Correlation of cellular immunity with human papillomavirus 16 status and outcome in patients with advanced oropharyngeal cancer

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12 December 2020

Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice

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12 December 2020

p16 expression as a surrogate marker for HPV-related oropharyngeal carcinoma: a guide for interpretative relevance and consistency.

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12 December 2020

Molecular classification identifies a subset of human papillomavirus--associated oropharyngeal cancers with favorable prognosis

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12 December 2020

MHC class I expression in HPV positive and negative tonsillar squamous cell carcinoma in correlation to clinical outcome

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12 December 2020

Prognostic biomarkers of survival in oropharyngeal squamous cell carcinoma: systematic review and meta-analysis.

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12 December 2020

Human papillomavirus in head and neck cancer: its role in pathogenesis and clinical implications

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12 December 2020

Diagnostic utility of p16INK4a: a reappraisal of its use in cervical biopsies

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12 December 2020

Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck

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12 December 2020

Detection of transcriptionally active high-risk HPV in patients with head and neck squamous cell carcinoma as visualized by a novel E6/E7 mRNA in situ hybridization method

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12 December 2020

p16 positive oropharyngeal squamous cell carcinoma:an entity with a favorable prognosis regardless of tumor HPV status

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12 December 2020

Comparative genomic hybridization analysis of tonsillar cancer reveals a different pattern of genomic imbalances in human papillomavirus-positive and -negative tumors

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12 December 2020

High incidence of high-risk HPV in benign and malignant lesions of the larynx.

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12 December 2020

[Aberrant expression and correlative analysis of P16 in breast cancers]

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12 December 2020

High-Risk Human Papillomavirus Affects Prognosis in Patients With Surgically Treated Oropharyngeal Squamous Cell Carcinoma

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12 December 2020

The role of Human papillomavirus in head and neck cancer and the impact on radiotherapy outcome

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12 December 2020

p16 INK4A overexpression is frequently detected in tumour-free tonsil tissue without association with HPV.

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12 December 2020

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

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12 December 2020

Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancers

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12 December 2020

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product

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12 December 2020

Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial.

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12 December 2020

Inhibition of cyclin D-CDK4/CDK6 activity is associated with an E2F-mediated induction of cyclin kinase inhibitor activity.

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12 December 2020

Expression status of p16 protein is associated with human papillomavirus oncogenic potential in cervical and genital lesions

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12 December 2020

Human papillomavirus type 16 infection and squamous cell carcinoma of the head and neck in never-smokers: a matched pair analysis

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12 December 2020

A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen.

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12 December 2020

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

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12 December 2020

High-risk human papillomavirus E6/E7 mRNA detection by a novel in situ hybridization assay strongly correlates with p16 expression and patient outcomes in oropharyngeal squamous cell carcinoma.

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12 December 2020

Viral RNA patterns and high viral load reliably define oropharynx carcinomas with active HPV16 involvement.

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12 December 2020

Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas

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12 December 2020

HPV-associated head and neck cancer: a virus-related cancer epidemic

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12 December 2020

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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12 December 2020

HPV status of oropharyngeal cancer by combination HPV DNA/p16 testing: biological relevance of discordant results.

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12 December 2020

A comparison of clinically utilized human papillomavirus detection methods in head and neck cancer

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12 December 2020

Clinically significant human papilloma virus in squamous cell carcinoma of the head and neck in UK practice.

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12 December 2020

Two major pathways of penile carcinogenesis: HPV-induced penile cancers overexpress p16ink4a, HPV-negative cancers associated with dermatoses express p53, but lack p16ink4a overexpression

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12 December 2020

Risk of high-grade cervical intraepithelial neoplasia during follow-up in HPV-positive women according to baseline p16-INK4A results: a prospective analysis of a nested substudy of the NTCC randomised controlled trial.

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12 December 2020

Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A

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12 December 2020

Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial

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12 December 2020

HPV-associated p16-expression and response to hypoxic modification of radiotherapy in head and neck cancer

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12 December 2020

Age, sexual behavior and human papillomavirus infection in oral cavity and oropharyngeal cancers

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12 December 2020

p16(INK4a) immunohistochemistry is a promising biomarker to predict the outcome of low grade cervical intraepithelial neoplasia: comparison study with HPV genotyping

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12 December 2020

New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections

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12 December 2020

Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials

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12 December 2020

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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12 December 2020

Serologic response to human oncogenic papillomavirus types 16, 18, 31, 33, 39, 58 and 59 virus-like particles in colombian women with invasive cervical cancer

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12 December 2020

Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination

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12 December 2020

Expression of p16 and lack of pRB in primary small cell lung cancer

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12 December 2020

Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy

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12 December 2020

Discrimination of 'driver' and 'passenger' HPV in tonsillar carcinomas by the polymerase chain reaction, chromogenic in situ hybridization, and p16(INK4a) immunohistochemistry

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12 December 2020

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity

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12 December 2020

Head and neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value

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12 December 2020

Identifiers

DOI

10.1111/CAS.12287

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30 August 2017

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