The impact of hypoxia on cell death pathways (Q38091503)

28 August 2017

The impact of hypoxia on cell death pathways (English)

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28 August 2017

1 reference

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Colin R Lenihan

1

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PubMed ID

23514172

28 August 2017

Cormac T Taylor

series ordinal

2

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28 August 2017

1 April 2013

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Biochemical Society Transactions

28 August 2017

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28 August 2017

41

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28 August 2017

2

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28 August 2017

657-663

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Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

28 August 2017

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Programmed cell death in animal development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The Fas signaling pathway: more than a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20120345

Cell death: critical control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Role of Bax and Bak in mitochondrial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Caspases and kinases in a death grip

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Life and death in peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia of the renal medulla--its implications for disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway

21 January 2018

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https://api.crossref.org/works/10.1042%2FBST20120345

Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Molecular ordering of hypoxia-induced apoptosis: critical involvement of the mitochondrial death pathway in a FADD/caspase-8 independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

BH3-only protein Noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The hypoxia-inducible factor-1 alpha is a negative factor for tumor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

BCL-xL is a target gene regulated by hypoxia-inducible factor-1{alpha}.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Living with p53, dying of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Suppression of hypoxia-inducible factor 2alpha restores p53 activity via Hdm2 and reverses chemoresistance of renal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Regulation of programmed cell death by NF-kappaB and its role in tumorigenesis and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

NF-κB inhibition compromises cardiac fibroblast viability under hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120345

21 January 2018

Identifiers

DOI

10.1042/BST20120345

1 reference

release_ychk5kjo5fbrdhbtw6hqpali4m

28 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ychk5kjo5fbrdhbtw6hqpali4m

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

23514172

1 reference

PubMed ID

23514172