Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins (Q38089906)

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scientific article published on 10 June 2009

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English	Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins	scientific article published on 10 June 2009

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scholarly article

1 reference

Europe PubMed Central

28 August 2017

Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins (English)

1 reference

Europe PubMed Central

28 August 2017

endoplasmic reticulum

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author name string

Donavon C Hiss

1

1 reference

Europe PubMed Central

28 August 2017

Gary A Gabriels

2

1 reference

Europe PubMed Central

28 August 2017

language of work or name

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publication date

10 June 2009

1 reference

Europe PubMed Central

28 August 2017

Expert Opinion on Drug Discovery

1 reference

Europe PubMed Central

28 August 2017

4

1 reference

Europe PubMed Central

28 August 2017

799-821

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Europe PubMed Central

28 August 2017

8

1 reference

Europe PubMed Central

28 August 2017

ER stress and the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress: cell life and death decisions.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

ER stress and diseases.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

ER-associated degradation in protein quality control and cellular regulation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cellular response to endoplasmic reticulum stress: a matter of life or death

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Coupling endoplasmic reticulum stress to the cell-death program: a novel HSP90-independent role for the small chaperone protein p23

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The endoplasmic reticulum stress response in immunity and autoimmunity

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Sarco/endoplasmic reticulum Ca2+ATPase type 3 isoforms (SERCA3b and SERCA3f): distinct roles in cell adhesion and ER stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Visiting the ER: the endoplasmic reticulum as a target for therapeutics in traffic related diseases

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A trip to the ER: coping with stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibitors: from research tools to drug candidates

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibition as a novel therapeutic target in human cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibitors: antitumor effects and beyond

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress increases the expression of methylenetetrahydrofolate reductase through the IRE1 transducer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Tunicamycin suppresses cisplatin-induced HepG2 cell apoptosis via enhancing p53 protein nuclear export

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress in health and disease

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

From acute ER stress to physiological roles of the Unfolded Protein Response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Unfolded protein response and cell death after depletion of brefeldin A-inhibited guanine nucleotide-exchange protein GBF1

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The endoplasmic reticulum and the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

GRP78 induction in cancer: therapeutic and prognostic implications.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

HSP105 interacts with GRP78 and GSK3 and promotes ER stress-induced caspase-3 activation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Ribosomal stress couples the unfolded protein response to p53-dependent cell cycle arrest

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53 and its isoforms in cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53-induced protein with a death domain (PIDD) isoforms differentially activate nuclear factor-kappaB and caspase-2 in response to genotoxic stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53: at the crossroad between cancer and ageing

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

3,3'-diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Roles of CHOP/GADD153 in endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Overview of cell death signaling pathways

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The unhydrolyzable fenretinide analogue 4-hydroxybenzylretinone induces the proapoptotic genes GADD153 (CHOP) and Bcl-2-binding component 3 (PUMA) and apoptosis that is caspase- dependent and independent of the retinoic acid receptor

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mechanisms of delivery of ubiquitylated proteins to the proteasome: new target for anti-cancer therapy?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Ubiquitin-dependent proteolysis: its role in human diseases and the design of therapeutic strategies

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The proteasome and proteasome inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Strategies for therapeutic targeting of the p53 pathway in cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A twist for survival and cancer progression

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

ZNF307, a novel zinc finger gene suppresses p53 and p21 pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53 in health and disease

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Caspase inhibitors: viral, cellular and chemical

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Drug discovery in the ubiquitin-proteasome system.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53 ubiquitination: Mdm2 and beyond

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Transcription factor TAFII250 promotes Mdm2-dependent turnover of p53

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The ubiquitin-proteasome pathway and its role in cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cancer biology: second step to retinal tumours.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Ubiquitin ligases: cell-cycle control and cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Alteration of cell-cycle regulation in epithelial ovarian cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cell cycle arrest and apoptotic induction in LNCaP cells by MCS-C2, novel cyclin-dependent kinase inhibitor, through p53/p21WAF1/CIP1 pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mdm2 is required for inhibition of Cdk2 activity by p21, thereby contributing to p53-dependent cell cycle arrest

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Caspases in cell survival, proliferation and differentiation.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53+/+ cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

In vivo evidence for binding of p53 to consensus binding sites in the p21 and GADD45 genes in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mechanistic studies of MDM2-mediated ubiquitination in p53 regulation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Small molecule protein-protein inhibitors for the p53-MDM2 interaction

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

MDMX overexpression prevents p53 activation by the MDM2 inhibitor Nutlin.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mdm2: p53's lifesaver?

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Gadd45a activation protects melanoma cells from ultraviolet B-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p53 and the pathogenesis of skin cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Molecular analysis of p53, MDM2 and H-ras genes in low-grade central osteosarcoma.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Therapeutic targets in the ARF tumor suppressor pathway.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

High levels of the p53 inhibitor MDM4 in head and neck squamous carcinomas

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Consequences of the loss of p53, RB1, and PTEN: relationship to gefitinib resistance in endometrial cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Restoration of wild-type p53 function in human cancer: relevance for tumor therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Small molecule inhibitors of the MDM2-p53 interaction discovered by ensemble-based receptor models.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

C-Abl as a modulator of p53.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The p53 network in head and neck cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Regulation of the p14ARF-Mdm2-p53 pathway: an overview in breast cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality: association with low p14(ARF) expression

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The p53/Mdm2/p14ARF cell cycle control pathway genes may be inactivated by genetic and epigenetic mechanisms in gliomas.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Classic and novel roles of p53: prospects for anticancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

p14ARF inhibits the growth of p53 deficient cells in a cell-specific manner

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Small molecules that reactivate mutant p53.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Restoration of wild-type p53 function in human tumors: strategies for efficient cancer therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Efficient C2 functionalisation of 2H-2-imidazolines.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Small molecule antagonists of the MDM2 oncoprotein as anticancer agents

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Targeting MDM2 and MDMX in retinoblastoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

E2F1 and E2F3 activate ATM through distinct mechanisms to promote E1A-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Identification of E2F1 as a positive transcriptional regulator for delta-catenin

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: markers with potential prognostic implications.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

E2F1-induced apoptosis: turning killers into therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Novel MDM2 p53-independent functions identified through RNA silencing technologies

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Transcriptional repression of the prosurvival endoplasmic reticulum chaperone GRP78/BIP by E2F1

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cyclin-dependent kinase inhibitors sensitize tumor cells to nutlin-induced apoptosis: a potent drug combination.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

(R)-roscovitine (CYC202, Seliciclib) sensitizes SH-SY5Y neuroblastoma cells to nutlin-3-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Nutlin-3 inhibits the NFkappaB pathway in a p53-dependent manner: implications in lung cancer therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Enhanced tumor cell kill by combined treatment with a small-molecule antagonist of mouse double minute 2 and adenoviruses encoding p53.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Phase I/II adenoviral p53 gene therapy for chemoradiation resistant advanced esophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Analysis of the MDM2 antagonist nutlin-3 in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The MDM-2 antagonist nutlin-3 promotes the maturation of acute myeloid leukemic blasts

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Nongenotoxic activation of the p53 pathway as a therapeutic strategy for multiple myeloma

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Diminished feedback regulation of proteasome expression and resistance to proteasome inhibitors in breast cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Myc suppresses induction of the growth arrest genes gadd34, gadd45, and gadd153 by DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

c-Myc represses the proximal promoters of GADD45a and GADD153 by a post-RNA polymerase II recruitment mechanism

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Growth and DNA damage-inducible transcription factor 153 mediates apoptosis in response to fenretinide but not synergy between fenretinide and chemotherapeutic drugs in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Fenretinide: a p53-independent way to kill cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Predictive value of GADD153, p21 and c-Jun for chemotherapy response in gastric cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Engineering responsiveness to cell culture stresses: growth arrest and DNA damage gene 153 (GADD153) and the unfolded protein response (UPR) in NS0 myeloma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Glucose-regulated protein GRP78 is up-regulated in prostate cancer and correlates with recurrence and survival.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Quantitative measurement of events in the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Stress induction of GRP78/BiP and its role in cancer.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Nelfinavir induces the unfolded protein response in ovarian cancer cells, resulting in ER vacuolization, cell cycle retardation and apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Elucidation of susceptible factors to endoplasmic reticulum stress-mediated anticancer activity in human hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Expression and clinical significance of glucose regulated proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A new tumor-specific variant of GRP78 as target for antibody-based therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Down-regulation of GRP78 is associated with the sensitivity of chemotherapy to VP-16 in small cell lung cancer NCI-H446 cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Highlights in experimental therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Hsp27 modulates p53 signaling and suppresses cellular senescence

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Heat shock proteins in the regulation of apoptosis: new strategies in tumor therapy: a comprehensive review

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Message in a bottle: role of the 70-kDa heat shock protein family in anti-tumor immunity

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

New approaches to molecular cancer therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Regulation of apoptosis proteins in cancer cells by ubiquitin

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Hsp60 regulation of tumor cell apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Heat shock protein 90 as a molecular target for cancer therapeutics

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Altered states: selectively drugging the Hsp90 cancer chaperone

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Inhibitors of the HSP90 molecular chaperone: current status

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

17-(Allylamino)-17-demethoxygeldanamycin activity in human melanoma models

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

GRP78 is overexpressed in glioblastomas and regulates glioma cell growth and apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress and unfolded protein response in Atm-deficient thymocytes and thymic lymphoma cells are attributable to oxidative stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The unfolded protein response during prostate cancer development

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Inhibition of MEK blocks GRP78 up-regulation and enhances apoptosis induced by ER stress in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

PERK-dependent regulation of IAP translation during ER stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Hypoxia and the unfolded protein response.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

"Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Targeting XBP-1 as a novel anti-cancer strategy.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Preventing oxidative stress: a new role for XBP1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

SAR study of a novel triene-ansamycin group compound, quinotrierixin, and related compounds, as inhibitors of ER stress-induced XBP1 activation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Untangling the unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Effect on tumor cells of blocking survival response to glucose deprivation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Biotin supplementation decreases the expression of the SERCA3 gene (ATP2A3) in Jurkat cells, thus, triggering unfolded protein response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibitor induces apoptosis through induction of endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress is a target for therapy in Waldenstrom macroglobulinemia.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress as a correlate of cytotoxicity in human tumor cells exposed to diindolylmethane in vitro

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress induced by aqueous extracts of cigarette smoke in 3T3 cells activates the unfolded-protein-response-dependent PERK pathway of cell survival

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cell cycle-related signaling pathways modulated by peripheral benzodiazepine receptor ligands in colorectal cancer cells.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Norepinephrine-induced oxidative stress causes PC-12 cell apoptosis by both endoplasmic reticulum stress and mitochondrial intrinsic pathway: inhibition of phosphatidylinositol 3-kinase survival pathway.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Insulin induces chaperone and CHOP gene expressions in adipocytes.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Suppression of cytokine responses by indomethacin in podocytes: a mechanism through induction of unfolded protein response.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Efficacy of single-agent bortezomib vs. single-agent thalidomide in patients with relapsed or refractory multiple myeloma: a systematic comparison

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Myeloma bone disease and proteasome inhibition therapies.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Proteasome inhibitor lactacystin disturbs the intracellular calcium homeostasis of dopamine neurons in ventral mesencephalic cultures.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The mammalian endoplasmic reticulum stress response element consists of an evolutionarily conserved tripartite structure and interacts with a novel stress-inducible complex

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Mechanisms of resistance and adaptation to thapsigargin in androgen-independent prostate cancer PC3 and DU145 cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

The sarco/endoplasmic reticulum calcium-ATPase 2b is an endoplasmic reticulum stress-inducible protein

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

IL-1beta caused pancreatic beta-cells apoptosis is mediated in part by endoplasmic reticulum stress via the induction of endoplasmic reticulum Ca2+ release through the c-Jun N-terminal kinase pathway

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

IPI-504, a novel and soluble HSP-90 inhibitor, blocks the unfolded protein response in multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Independent signaling of grp78 gene transcription and phosphorylation of eukaryotic initiator factor 2 alpha by the stressed endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Pathological investigation of oxidative stress in the post-genomic era.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Redox-based regulation of signal transduction: principles, pitfalls, and promises

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Endoplasmic reticulum stress is involved in hydrogen peroxide induced apoptosis in immortalized and malignant human oral keratinocytes

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

A pivotal role for Mcl-1 in Bortezomib-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Controlling protein compartmentalization to overcome disease

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Bortezomib in relapsed or refractory Waldenström's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Potential new therapeutics for Waldenstrom's macroglobulinemia

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Cancer drug discovery: the wisdom of imprecision

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Levels of HdmX Expression Dictate the Sensitivity of Normal and Transformed Cells to Nutlin-3

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Antiangiogenic Activity of the MDM2 Antagonist Nutlin-3

1 reference

https://api.crossref.org/works/10.1517%2F17460440903052559

21 January 2018

Identifiers

10.1517/17460440903052559

1 reference

Europe PubMed Central

28 August 2017

1 reference

Europe PubMed Central

28 August 2017

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