Using C. elegans to decipher the cellular and molecular mechanisms underlying neurodevelopmental disorders (Q38089667)

28 August 2017

Using C. elegans to decipher the cellular and molecular mechanisms underlying neurodevelopmental disorders (English)

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neurodevelopmental disorder

28 August 2017

Caenorhabditis elegans

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1

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28 August 2017

2

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28 August 2017

Ana João Rodrigues

3

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publication date

14 March 2013

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28 August 2017

Molecular Neurobiology

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28 August 2017

48

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28 August 2017

465-489

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28 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s12035-013-8434-6

28 August 2017

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Visualization of synaptic specializations in live C. elegans with synaptic vesicle protein-GFP fusions

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Factors regulating the abundance and localization of synaptobrevin in the plasma membrane.

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An RNAi screen identifies genes that regulate GABA synapses.

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Identification of genes involved in synaptogenesis using a fluorescent active zone marker in Caenorhabditis elegans.

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The presynaptic dense projection of the Caenorhabditis elegans cholinergic neuromuscular junction localizes synaptic vesicles at the active zone through SYD-2/liprin and UNC-10/RIM-dependent interactions

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Systematic analysis of genes required for synapse structure and function.

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Ionotropic glutamate receptors in Caenorhabditis elegans

21 January 2018

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Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

21 January 2018

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A new group-training procedure for habituation demonstrates that presynaptic glutamate release contributes to long-term memory in Caenorhabditis elegans

21 January 2018

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Mechanism of extrasynaptic dopamine signaling in Caenorhabditis elegans

21 January 2018

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Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans.

21 January 2018

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The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration

21 January 2018

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EXP-1 is an excitatory GABA-gated cation channel

21 January 2018

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The composition of the GABA receptor at the Caenorhabditis elegans neuromuscular junction

21 January 2018

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Pharmacological characterization of the homomeric and heteromeric UNC-49 GABA receptors in C. elegans

21 January 2018

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The GABA nervous system in C. elegans

21 January 2018

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Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family

21 January 2018

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daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway

21 January 2018

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Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

21 January 2018

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A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

21 January 2018

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

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Fluoxetine-resistance genes in Caenorhabditis elegans function in the intestine and may act in drug transport

21 January 2018

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Fluoxetine-resistant mutants in C. elegans define a novel family of transmembrane proteins

21 January 2018

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Cocaine modulates locomotion behavior in C. elegans

21 January 2018

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Caenorhabditis elegans: a versatile platform for drug discovery

21 January 2018

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Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans

21 January 2018

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Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans

21 January 2018

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Caenorhabditis elegans senses protons through amphid chemosensory neurons: proton signals elicit avoidance behavior.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Regulation of lifespan by sensory perception in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Regulation of Drosophila life span by olfaction and food-derived odors.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetic control of temperature preference in the nematode Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The G-protein gamma subunit gpc-1 of the nematode C.elegans is involved in taste adaptation

21 January 2018

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Neural regulation of thermotaxis in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Natural variation in a neuropeptide Y receptor homolog modifies social behavior and food response in C. elegans

21 January 2018

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NPY and Y receptors: lessons from transgenic and knockout models

21 January 2018

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The effects of social isolation on neuropeptide Y levels, exploratory and anxiety-related behaviors in rats

21 January 2018

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Effects of a selective Y2R antagonist, JNJ-31020028, on nicotine abstinence-related social anxiety-like behavior, neuropeptide Y and corticotropin releasing factor mRNA levels in the novelty-seeking phenotype

21 January 2018

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Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Loss of the putative RNA-directed RNA polymerase RRF-3 makes C. elegans hypersensitive to RNAi.

21 January 2018

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Efficient and cell specific knock-down of gene function in targeted C. elegans neurons.

21 January 2018

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Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes

21 January 2018

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Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans

21 January 2018

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Temperature sensing by an olfactory neuron in a circuit controlling behavior of C. elegans.

21 January 2018

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Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Bridging the gap between genes and behavior: recent advances in the electrophysiological analysis of neural function in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Single ionic channels of two Caenorhabditis elegans chemosensory neurons in native membrane.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Active currents regulate sensitivity and dynamic range in C. elegans neurons

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The C. elegans thermosensory neuron AFD responds to warming.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetically targeted cell disruption in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Photo-inducible cell ablation in Caenorhabditis elegans using the genetically encoded singlet oxygen generating protein miniSOG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Axon regeneration requires a conserved MAP kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Multimodal fast optical interrogation of neural circuitry

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The neural circuits and sensory channels mediating harsh touch sensation in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Optogenetic analysis of synaptic function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Optical silencing of C. elegans cells with arch proton pump

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Laterally orienting C. elegans using geometry at microscale for high-throughput visual screens in neurodegeneration and neuronal development studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

OrthoList: a compendium of C. elegans genes with human orthologs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Assessment of normal and mutant human presenilin function in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Presenilin is required for proper morphology and function of neurons in C. elegans.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans: rescue by the DAF-16 and HSF-1 pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Functional genomics and biochemical characterization of the C. elegans orthologue of the Machado-Joseph disease protein ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

SUT-1 enables tau-induced neurotoxicity in C. elegans.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetics and pathogenesis of polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Cilia in the nervous system: linking cilia function and neurodevelopmental disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetics of idiopathic epilepsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genes associated with idiopathic epilepsies: a current overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Exploring New Gene Discoveries in Idiopathic Generalized Epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Deletion of the K(V)1.1 potassium channel causes epilepsy in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Voltage-gated calcium channels and idiopathic generalized epilepsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Epileptic-like convulsions associated with LIS-1 in the cytoskeletal control of neurotransmitter signaling in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Intestinal Ca2+ wave dynamics in freely moving C. elegans coordinate execution of a rhythmic motor program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Zn2+ ions: modulators of excitatory and inhibitory synaptic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

15q13.3 microdeletions increase risk of idiopathic generalized epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Neuronal nicotinic acetylcholine receptors: from the genetic analysis to neurological diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: nicotinic acetylcholine receptors, a case study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Nicotinic acetylcholine receptors in the nematode Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The Ror receptor tyrosine kinase CAM-1 is required for ACR-16-mediated synaptic transmission at the C. elegans neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Wnt-7a induces presynaptic colocalization of alpha 7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Wnt signaling regulates acetylcholine receptor translocation and synaptic plasticity in the adult nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

n-Sec1: a neural-specific syntaxin-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Defects in synaptic vesicle docking in unc-18 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

UNC-18 promotes both the anterograde trafficking and synaptic function of syntaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Syntaxin 1A interacts with multiple exocytic proteins to regulate neurotransmitter release in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Conformational switch of syntaxin-1 controls synaptic vesicle fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Synaptic assembly of the brain in the absence of neurotransmitter secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

TUBA1A mutations cause wide spectrum lissencephaly (smooth brain) and suggest that multiple neuronal migration pathways converge on alpha tubulins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Human doublecortin (DCX) and the homologous gene in mouse encode a putative Ca2+-dependent signaling protein which is mutated in human X-linked neuronal migration defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Calcium signalling in the guidance of nerve growth by netrin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetic interactions among cortical malformation genes that influence susceptibility to convulsions in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Pharmacogenetic analysis reveals a post-developmental role for Rac GTPases in Caenorhabditis elegans GABAergic neurotransmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Valproic acid extends Caenorhabditis elegans lifespan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Anticonvulsant medications extend worm life-span

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Cross-species functional genomic analysis identifies resistance genes of the histone deacetylase inhibitor valproic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Side effects of levamisole in children with nephrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Analysis of the neuroligin 4Y gene in patients with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

SHANK1 Deletions in Males with Autism Spectrum Disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Disruption of neurexin 1 associated with autism spectrum disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Functional phenotypic rescue of Caenorhabditis elegans neuroligin-deficient mutants by the human and rat NLGN1 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Neuroligin-deficient mutants of C. elegans have sensory processing deficits and are hypersensitive to oxidative stress and mercury toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Practice parameter: screening and diagnosis of autism: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The neurexin superfamily of Caenorhabditis elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Regulation of dendritic spine morphology and synaptic function by Shank and Homer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

SHN-1, a Shank homologue in C. elegans, affects defecation rhythm via the inositol-1,4,5-trisphosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

ANK repeat-domain of SHN-1 Is indispensable for in vivo SHN-1 function in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The neurobeachin gene is disrupted by a translocation in a patient with idiopathic autism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The autism candidate gene Neurobeachin encodes a scaffolding protein implicated in membrane trafficking and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

SEL-2, the C. elegans neurobeachin/LRBA homolog, is a negative regulator of lin-12/Notch activity and affects endosomal traffic in polarized epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The immunoglobulin superfamily of neuronal cell adhesion molecules: lessons from animal models and correlation with human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Aberrant splicing of neural cell adhesion molecule L1 mRNA in a family with X-linked hydrocephalus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Association of the neuronal cell adhesion molecule (NRCAM) gene variants with autism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A role for the C. elegans L1CAM homologue lad-1/sax-7 in maintaining tissue attachment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Maintenance of neuronal positions in organized ganglia by SAX-7, a Caenorhabditis elegans homologue of L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Functional dissection of the C. elegans cell adhesion molecule SAX-7, a homologue of human L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2 mediated axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Dual functional activity of semaphorin 3B is required for positioning the anterior commissure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Close homolog of L1 and neuropilin 1 mediate guidance of thalamocortical axons at the ventral telencephalon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Altered distribution of dopaminergic neurons in the brain of L1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

NrCAM deletion causes topographic mistargeting of thalamocortical axons to the visual cortex and disrupts visual acuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Developmental control of foraging and social behavior by the Drosophila neuropeptide Y-like system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Schizophrenia-relevant behaviours in a genetic mouse model for Y2 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genetic and epigenetic defects in mental retardation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

ASPM is a major determinant of cerebral cortical size

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Screening of mutations in the PHF8 gene and identification of a novel mutation in a Finnish family with XLMR and cleft lip/cleft palate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Regulation of chemosensory and GABAergic motor neuron development by the C. elegans Aristaless/Arx homolog alr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Motor neuron synapse and axon defects in a C. elegans alpha-tubulin mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Down's syndrome: critical genes in a critical region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

New cerebellar phenotypes in YAC transgenic mouse in vivo library of human Down syndrome critical region-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mental retardation and associated neurological dysfunctions in Down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

DYRK1A (dual-specificity tyrosine-phosphorylated and -regulated kinase 1A): a gene with dosage effect during development and neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Function and regulation of Dyrk1A: towards understanding Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Calcineurin regulation of neuronal plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

NFAT signaling in neural development and axon growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The Caenorhabditis elegans homologue of Down syndrome critical region 1, RCN-1, inhibits multiple functions of the phosphatase calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in the polyglutamine binding protein 1 gene cause X-linked mental retardation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Novel truncating mutations in the polyglutamine tract binding protein 1 gene (PQBP1) cause Renpenning syndrome and X-linked mental retardation in another family with microcephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Golabi-Ito-Hall syndrome results from a missense mutation in the WW domain of the PQBP1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Nematode homologue of PQBP1, a mental retardation causative gene, is involved in lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Alpha thalassaemia-mental retardation, X linked

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

ATRX encodes a novel member of the SNF2 family of proteins: mutations point to a common mechanism underlying the ATR-X syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

lin-35/Rb and xnp-1/ATR-X function redundantly to control somatic gonad development in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

XNP-1/ATR-X acts with RB, HP1 and the NuRD complex during larval development in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The DISC locus in psychiatric illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Small-molecule proteostasis regulators for protein conformational diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Polymorphisms in CACNA1E and Camk2d are associated with seizure susceptibility of Sprague-Dawley rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The doublecortin-related gene zyg-8 is a microtubule organizer in Caenorhabditis elegans neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Abnormal network activity in a targeted genetic model of human double cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Human mutations in NDE1 cause extreme microcephaly with lissencephaly [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutations in DYNC1H1 cause severe intellectual disability with neuronal migration defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Caenorhabditis elegans aristaless/Arx gene alr-1 restricts variable gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The Caenorhabditis elegans aristaless orthologue, alr-1, is required for maintaining the functional and structural integrity of the amphid sensory organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation of NPR-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Drosophila GABAergic systems. II. Mutational analysis of chromosomal segment 64AB, a region containing the glutamic acid decarboxylase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Mutation of GABRA1 in an autosomal dominant form of juvenile myoclonic epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

A small-molecule screen in C. elegans yields a new calcium channel antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-013-8434-6

The neural circuit for touch sensitivity in Caenorhabditis elegans

21 January 2018

1 reference

12 December 2020

The posterior nervous system of the nematode Caenorhabditis elegans: serial reconstruction of identified neurons and complete pattern of synaptic interactions.

1 reference

12 December 2020

Subunit-dependent modulation of neuronal nicotinic receptors by zinc.

1 reference

12 December 2020

In vivo laser axotomy in C. elegans

1 reference

12 December 2020

The C. elegans unc-18 gene encodes a protein expressed in motor neurons

1 reference

12 December 2020

rugose (rg), a Drosophila A kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways

1 reference

12 December 2020

Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron.

1 reference

12 December 2020

Human vesicular glutamate transporters functionally complement EAT-4 in C. elegans.

1 reference

12 December 2020

Mutations of the caenorhabditis elegans brain-specific inorganic phosphate transporter eat-4 affect habituation of the tap-withdrawal response without affecting the response itself.

1 reference

12 December 2020

EAT-4, a homolog of a mammalian sodium-dependent inorganic phosphate cotransporter, is necessary for glutamatergic neurotransmission in caenorhabditis elegans

1 reference

12 December 2020

Mutations that prevent associative learning in C. elegans.

1 reference

12 December 2020

An extensive and diverse gene family of nicotinic acetylcholine receptor alpha subunits in Caenorhabditis elegans.

1 reference

12 December 2020

The genetics of feeding in Caenorhabditis elegans.

1 reference

12 December 2020

Uses of GFP in Caenorhabditis elegans

1 reference

12 December 2020

[Acute levamisole poisoning]

1 reference

12 December 2020

A retrograde signal is involved in activity-dependent remodeling at a C. elegans neuromuscular junction.

1 reference

12 December 2020

Genes required for axon pathfinding and extension in the C. elegans nerve ring

1 reference

12 December 2020

A missense mutation confirms the L1 defect in X-linked hydrocephalus (HSAS)

1 reference

12 December 2020

Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations

1 reference

12 December 2020

Tight-seal whole-cell patch clamping of Caenorhabditis elegans neurons

1 reference

12 December 2020

GLR-1, a Non-NMDA Glutamate Receptor Homolog, Is Critical for Long-Term Memory inCaenorhabditis elegans

1 reference

12 December 2020

Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity

1 reference

12 December 2020

Progressive neurodegeneration in C. elegans model of tauopathy

1 reference

12 December 2020

Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic

1 reference

12 December 2020

Mice lacking the beta3 subunit of the GABAA receptor have the epilepsy phenotype and many of the behavioral characteristics of Angelman syndrome.

1 reference

12 December 2020

Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans

1 reference

12 December 2020

The worm in us - Caenorhabditis elegans as a model of human disease

1 reference

12 December 2020

Neurophysiological methods in C. elegans: an introduction

1 reference

12 December 2020

The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans

1 reference

12 December 2020

Oxidative stress in autism

1 reference

12 December 2020

Plasticity of chemotaxis revealed by paired presentation of a chemoattractant and starvation in the nematode Caenorhabditis elegans.

1 reference

12 December 2020

1 reference

12 December 2020

Osmotic avoidance defective mutants of the nematode Caenorhabditis elegans

1 reference

12 December 2020

Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans

1 reference

12 December 2020

Normalization of Dyrk1A expression by AAV2/1-shDyrk1A attenuates hippocampal-dependent defects in the Ts65Dn mouse model of Down syndrome.

1 reference

12 December 2020

GABA receptors containing Rdl subunits mediate fast inhibitory synaptic transmission in Drosophila neurons.

1 reference

12 December 2020

ATX-3, CDC-48 and UBXN-5: A new trimolecular complex in Caenorhabditis elegans

1 reference

12 December 2020

Integration of mechanosensory stimuli in Caenorhabditis elegans.

1 reference

12 December 2020

Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A.

1 reference

12 December 2020

1 reference

12 December 2020

The Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic development.

1 reference

12 December 2020

1 reference

12 December 2020

Identification of neuroprotective compounds of caenorhabditis elegans dopaminergic neurons against 6-OHDA

1 reference

12 December 2020

Ionotropic glutamate receptors: genetics, behavior and electrophysiology

1 reference

12 December 2020

Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance

1 reference

12 December 2020

The integration of antagonistic reflexes revealed by laser ablation of identified neurons determines habituation kinetics of the Caenorhabditis elegans tap withdrawal response

1 reference

12 December 2020

Osmotic avoidance in Caenorhabditis elegans: synaptic function of two genes, orthologues of human NRXN1 and NLGN1, as candidates for autism.

1 reference

12 December 2020

Stages of memory in the nematode Caenorhabditis elegans

1 reference

12 December 2020

Biogenic amine neurotransmitters in C. elegans

1 reference

12 December 2020

Differential expression of glutamate receptor subunits in the nervous system of Caenorhabditis elegans and their regulation by the homeodomain protein UNC-42.

1 reference

12 December 2020

A polycystic kidney-disease gene homologue required for male mating behaviour in C. elegans

1 reference

12 December 2020

CRASH syndrome: clinical spectrum of corpus callosum hypoplasia, retardation, adducted thumbs, spastic paraparesis and hydrocephalus due to mutations in one single gene, L1.

1 reference

12 December 2020

1 reference

12 December 2020

npr-1 Regulates foraging and dispersal strategies in Caenorhabditis elegans

1 reference

12 December 2020

A mutation in the AMPA-type glutamate receptor, glr-1, blocks olfactory associative and nonassociative learning in Caenorhabditis elegans

1 reference

12 December 2020

Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.

1 reference

12 December 2020

10.1007/S12035-013-8434-6

Identifiers

DOI

1 reference

PubMed ID

23494747

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23494747