Mitochondrial dysfunction in psychiatric and neurological diseases: cause(s), consequence(s), and implications of antioxidant therapy (Q38086474)

28 August 2017

Mitochondrial dysfunction in psychiatric and neurological diseases: cause(s), consequence(s), and implications of antioxidant therapy (English)

1 reference

28 August 2017

Deepak M Kasote

1

1 reference

PubMed ID

23460132

28 August 2017

Mahabaleshwar V Hegde

series ordinal

2

1 reference

PubMed ID

23460132

28 August 2017

Surendra S Katyare

series ordinal

3

1 reference

28 August 2017

5 March 2013

1 reference

28 August 2017

1 reference

28 August 2017

39

1 reference

28 August 2017

392-406

1 reference

28 August 2017

4

1 reference

Mitochondria: dynamic organelles in disease, aging, and development

28 August 2017

1 reference

Abnormal mitochondrial dynamics and neurodegenerative diseases

21 January 2018

1 reference

Assessing mitochondrial dysfunction in cells.

21 January 2018

1 reference

Mitochondrial dysfunction and molecular pathways of disease

21 January 2018

1 reference

Neuroanatomical pattern of mitochondrial complex I pathology varies between schizophrenia, bipolar disorder and major depression

21 January 2018

1 reference

Effect of thyroid deficiency on oxidative phosphorylation in rat liver, kidney, and brain mitochondria.

21 January 2018

1 reference

21 January 2018

1 reference

The role of mitochondria in inherited neurodegenerative diseases

21 January 2018

1 reference

The other, forgotten genome: mitochondrial DNA and mental disorders

21 January 2018

1 reference

Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders

21 January 2018

1 reference

Disorders from perturbations of nuclear-mitochondrial intergenomic cross-talk.

21 January 2018

1 reference

Therapeutic prospects for mitochondrial disease

21 January 2018

1 reference

Cell cycle activation linked to neuronal cell death initiated by DNA damage

21 January 2018

1 reference

Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

1 reference

Superoxide production by the mitochondrial respiratory chain

21 January 2018

1 reference

Mitochondrial dysfunction in human pathologies.

21 January 2018

1 reference

Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.

21 January 2018

1 reference

Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients

21 January 2018

1 reference

Oxidative stress in psychiatric disorders: evidence base and therapeutic implications

21 January 2018

1 reference

Glutathione, oxidative stress and neurodegeneration

21 January 2018

1 reference

Mitochondrial fission in apoptosis, neurodegeneration and aging

21 January 2018

1 reference

21 January 2018

1 reference

Mitochondria and neurotransmission: evacuating the synapse

21 January 2018

1 reference

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

21 January 2018

1 reference

Mitochondria as a therapeutic target for aging and neurodegenerative diseases

21 January 2018

1 reference

Ca2+-dependent mechanisms of presynaptic control at central synapses

21 January 2018

1 reference

Mitochondrial dysfunction and intracellular calcium dysregulation in ALS

21 January 2018

1 reference

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

21 January 2018

1 reference

Mitochondrial calcium homeostasis as potential target for mitochondrial medicine

21 January 2018

1 reference

Effect of corticosterone treatment on mitochondrial oxidative energy metabolism in developing rat brain.

21 January 2018

1 reference

Estrogenic control of mitochondrial function and biogenesis

21 January 2018

1 reference

Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

21 January 2018

1 reference

The neurological disorder associated with thyroid autoimmunity

21 January 2018

1 reference

Effect of experimental thyrotoxicosis on oxidative phosphorylation in rat liver, kidney and brain mitochondria

21 January 2018

1 reference

Influence of thyroid hormone treatment on the respiratory activity of cerebral mitochondria from hypothyroid rats. A critical re-assessment

21 January 2018

1 reference

Brain bioenergetics and response to triiodothyronine augmentation in major depressive disorder

21 January 2018

1 reference

Localization of glucocorticoid hormone receptors in mitochondria of human cells

21 January 2018

1 reference

Localization of the glucocorticoid receptor in rat brain mitochondria.

21 January 2018

1 reference

Dynamic regulation of mitochondrial function by glucocorticoids

21 January 2018

1 reference

Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants.

21 January 2018

1 reference

Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

21 January 2018

1 reference

Effects of glucocorticoids on oxidative stress-induced hippocampal cell death: implications for the pathogenesis of Alzheimer's disease.

21 January 2018

1 reference

Mitochondrial mechanisms of estrogen neuroprotection

21 January 2018

1 reference

Estrogen and the regulation of mitochondrial structure and function in the brain

21 January 2018

1 reference

Progesterone and Cerebral Function during Emotion Processing in Men and Women with Schizophrenia

21 January 2018

1 reference

Substrate-specific stimulation by glucagon of isolated murine brain mitochondrial oxidative phosphorylation

21 January 2018

1 reference

Ethanol impairs insulin-stimulated mitochondrial function in cerebellar granule neurons

21 January 2018

1 reference

Effect of alloxan-diabetes and subsequent treatment with insulin on lipid/phospholipid composition of rat brain microsomes and mitochondria.

21 January 2018

1 reference

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease.

21 January 2018

1 reference

Glucagon stimulates ketone utilization by rat brain slices

21 January 2018

1 reference

Identification of glucagon receptors in rat brain

21 January 2018

1 reference

Desensitization of the neuronal insulin receptor: a new approach in the etiopathogenesis of late-onset sporadic dementia of the Alzheimer type (SDAT)?

21 January 2018

1 reference

Loss of insulin receptor immunoreactivity from the substantia nigra pars compacta neurons in Parkinson's disease.

21 January 2018

1 reference

Essential fatty acids, lipid membrane abnormalities, and the diagnosis and treatment of schizophrenia

21 January 2018

1 reference

Structural and functional alterations in mitochondrial membrane in picrotoxin-induced epileptic rat brain

21 January 2018

1 reference

Mitochondrial membrane permeabilization in cell death

21 January 2018

1 reference

Mitochondria: mitochondrial membranes in brain ageing and neurodegeneration.

21 January 2018

1 reference

Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta

21 January 2018

1 reference

Activation of the mitochondrial permeability transition pore modulates Ca2+ responses to physiological stimuli in adult neurons

21 January 2018

1 reference

Genetic inactivation of mitochondria-targeted redox enzyme p66ShcA preserves neuronal viability and mitochondrial integrity in response to oxidative challenges

21 January 2018

1 reference

Ageing-induced alterations in lipid/phospholipid profiles of rat brain and liver mitochondria: implications for mitochondrial energy-linked functions

21 January 2018

1 reference

Alpha-synuclein in Lewy body disease and Alzheimer's disease

21 January 2018

1 reference

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

21 January 2018

1 reference

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

1 reference

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

Delaying the mitochondrial decay of aging

21 January 2018

1 reference

Mitochondria as sources and targets of damage in cellular aging

21 January 2018

1 reference

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

21 January 2018

1 reference

Deceleration of fusion-fission cycles improves mitochondrial quality control during aging

21 January 2018

1 reference

Mitochondrial membrane fluidity and oxidative damage to mitochondrial DNA in aged and AD human brain.

21 January 2018

1 reference

Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: implications for aging

21 January 2018

1 reference

Mitochondrial transcription factor A overexpression and base excision repair deficiency in the inner ear of rats with D-galactose-induced aging.

21 January 2018

1 reference

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

1 reference

Mitochondria in neuroplasticity and neurological disorders

21 January 2018

1 reference

Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease.

21 January 2018

1 reference

Parkinson's disease and mitochondrial complex I: a perspective on the Ndi1 therapy

21 January 2018

1 reference

Origin and functional consequences of the complex I defect in Parkinson's disease

21 January 2018

1 reference

Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

21 January 2018

1 reference

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson's disease

21 January 2018

1 reference

Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

21 January 2018

1 reference

DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly

21 January 2018

1 reference

Parkinson's syndrome and Parkinson's disease in mitochondrial disorders

21 January 2018

1 reference

Mitochondrial quality control and Parkinson's disease: a pathway unfolds

21 January 2018

1 reference

A century of Alzheimer's disease

21 January 2018

1 reference

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

1 reference

Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria.

21 January 2018

1 reference

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease

21 January 2018

1 reference

Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

21 January 2018

1 reference

Reduced Activities of Thiamine-Dependent Enzymes in the Brains and Peripheral Tissues of Patients With Alzheimer's Disease

21 January 2018

1 reference

Brain Cytochrome Oxidase in Alzheimer's Disease

21 January 2018

1 reference

Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

1 reference

Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage

21 January 2018

1 reference

Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

21 January 2018

1 reference

21 January 2018

1 reference

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease.

21 January 2018

1 reference

Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease

21 January 2018

1 reference

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

21 January 2018

1 reference

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

21 January 2018

1 reference

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

21 January 2018

1 reference

State-dependent alterations in mitochondrial complex I activity in platelets: a potential peripheral marker for schizophrenia

21 January 2018

1 reference

Evidence for a mitochondrial oxidative phosphorylation defect in brains from patients with schizophrenia

21 January 2018

1 reference

Perturbation in mitochondrial network dynamics and in complex I dependent cellular respiration in schizophrenia

21 January 2018

1 reference

Expression analyses of the mitochondrial complex I 75-kDa subunit in early onset schizophrenia and autism spectrum disorder: increased levels as a potential biomarker for early onset schizophrenia.

21 January 2018

1 reference

New evidence for the involvement of mitochondrial inheritance in schizophrenia: results from a cross-sectional study evaluating the risk of illness in relatives of schizophrenia patients

21 January 2018

1 reference

Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

21 January 2018

1 reference

Elevated cerebrospinal fluid lactate concentrations in patients with bipolar disorder and schizophrenia: implications for the mitochondrial dysfunction hypothesis

21 January 2018

1 reference

Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

21 January 2018

1 reference

Role of mitochondrial DNA in calcium signaling abnormality in bipolar disorder.

21 January 2018

1 reference

Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

21 January 2018

1 reference

Mitochondrial energetics and therapeutics

21 January 2018

1 reference

alpha-Lipoic acid as a biological antioxidant

21 January 2018

1 reference

The effects and mechanisms of mitochondrial nutrient alpha-lipoic acid on improving age-associated mitochondrial and cognitive dysfunction: an overview

21 January 2018

1 reference

Mitochondria: a therapeutic target in neurodegeneration

21 January 2018

1 reference

Formulation of a medical food cocktail for Alzheimer's disease: beneficial effects on cognition and neuropathology in a mouse model of the disease

21 January 2018

1 reference

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy

21 January 2018

1 reference

Combined R-alpha-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson's disease.

21 January 2018

1 reference

Is it time to reassess alpha lipoic acid and niacinamide therapy in schizophrenia?

21 January 2018

1 reference

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

1 reference

The emerging role of coenzyme Q-10 in aging, neurodegeneration, cardiovascular disease, cancer and diabetes mellitus

21 January 2018

1 reference

Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients

21 January 2018

1 reference

Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease

21 January 2018

1 reference

Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases

21 January 2018

1 reference

Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease

21 January 2018

1 reference

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

21 January 2018

1 reference

Effect of vitamin E administration on the elevated oxygen stress and the telomeric and subtelomeric status in Alzheimer's disease.

21 January 2018

1 reference

Vitamin E therapy in Parkinson's disease

21 January 2018

1 reference

Effect of coenzyme Q10 and vitamin E on brain energy metabolism in the animal model of Huntington's disease

21 January 2018

1 reference

Supplementation with a combination of omega-3 fatty acids and antioxidants (vitamins E and C) improves the outcome of schizophrenia

21 January 2018

1 reference

Vitamin C enters mitochondria via facilitative glucose transporter 1 (Glut1) and confers mitochondrial protection against oxidative injury

21 January 2018

1 reference

Influence of vitamin E and C supplementation on lipoprotein oxidation in patients with Alzheimer's disease

21 January 2018

1 reference

Ascorbate treatment attenuates the Huntington behavioral phenotype in mice

21 January 2018

1 reference

Oxidative stress, α-tocopherol, ascorbic acid and reduced glutathione status in schizophrenics

21 January 2018

1 reference

Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia

21 January 2018

1 reference

Melatonin role in the mitochondrial function.

21 January 2018

1 reference

Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.

21 January 2018

1 reference

Melatonin as a pharmacological agent against neuronal loss in experimental models of Huntington's disease, Alzheimer's disease and parkinsonism

21 January 2018

1 reference

Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling

21 January 2018

1 reference

Melatonin and Parkinson's disease

21 January 2018

1 reference

Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity

21 January 2018

1 reference

Protective effect of melatonin on 3-nitropropionic acid-induced oxidative stress in synaptosomes in an animal model of Huntington's disease

21 January 2018

1 reference

Melatonin as a potential therapeutic agent in psychiatric illness.

21 January 2018

1 reference

Melatonin: an overlooked factor in schizophrenia and in the inhibition of anti-psychotic side effects

21 January 2018

1 reference

Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder.

21 January 2018

1 reference

Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development

21 January 2018

1 reference

Glutathione: a novel treatment target in psychiatry

21 January 2018

1 reference

Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary

21 January 2018

1 reference

Randomized, double-blind, pilot evaluation of intravenous glutathione in Parkinson's disease

21 January 2018

1 reference

Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia

21 January 2018

1 reference

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

21 January 2018

1 reference

Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models

21 January 2018

1 reference

Elevation of glutathione as a therapeutic strategy in Alzheimer disease

21 January 2018

1 reference

Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's dise

21 January 2018

1 reference

In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease.

21 January 2018

1 reference

N-Acetylcysteine reverses mitochondrial dysfunctions and behavioral abnormalities in 3-nitropropionic acid-induced Huntington's disease

21 January 2018

1 reference

N-acetyl cysteine restores brain glutathione loss in combined 2-cyclohexene-1-one and d-amphetamine-treated rats: relevance to schizophrenia and bipolar disorder

21 January 2018

1 reference

Targeting antioxidants to mitochondria by conjugation to lipophilic cations.

21 January 2018

1 reference

Mitochondrial medicine for aging and neurodegenerative diseases

21 January 2018

1 reference

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics

21 January 2018

1 reference

The mitochondrial antioxidants MitoE(2) and MitoQ(10) increase mitochondrial Ca(2+) load upon cell stimulation by inhibiting Ca(2+) efflux from the organelle

21 January 2018

1 reference

The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease.

21 January 2018

1 reference

Mitochondria-targeted antioxidant peptides.

21 January 2018

1 reference

Mitochondria-targeted peptide prevents mitochondrial depolarization and apoptosis induced by tert-butyl hydroperoxide in neuronal cell lines

21 January 2018

1 reference

Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

21 January 2018

1 reference

Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases

21 January 2018

1 reference

Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses

21 January 2018

1 reference

Oxidative stress and heart failure in altered thyroid States

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIOF.1093

1 reference

28 August 2017

1 reference

PubMed ID

23460132