Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail (Q38083799)

28 August 2017

Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail (English)

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28 August 2017

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4

Nada Jabado

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author name string

Adam M Fontebasso

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1

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PubMed ID

23432647

28 August 2017

Xiao-Yang Liu

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2

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PubMed ID

23432647

28 August 2017

Dominik Sturm

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3

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28 August 2017

1 March 2013

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28 August 2017

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28 August 2017

23

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28 August 2017

2

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28 August 2017

210-216

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

28 August 2017

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A distinct spectrum of copy number aberrations in pediatric high-grade gliomas

21 January 2018

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A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

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Update on molecular findings, management and outcome in low-grade gliomas

21 January 2018

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Loss of wild-type ATRX expression in somatic cell hybrids segregates with activation of Alternative Lengthening of Telomeres

21 January 2018

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A network model of a cooperative genetic landscape in brain tumors

21 January 2018

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Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3

21 January 2018

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Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.

21 January 2018

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Association of age at diagnosis and genetic mutations in patients with neuroblastoma.

21 January 2018

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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

21 January 2018

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The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

21 January 2018

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Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

21 January 2018

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New strategies in the molecular targeting of glioblastoma: how do you hit a moving target?

21 January 2018

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

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The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9

21 January 2018

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The Pediatric Cancer Genome Project

21 January 2018

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New functions for an old variant: no substitute for histone H3.3.

21 January 2018

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Brain cancer stem cells display preferential sensitivity to Akt inhibition

21 January 2018

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Molecular profiling identifies prognostic subgroups of pediatric glioblastoma and shows increased YB-1 expression in tumors.

21 January 2018

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Distinct factors control histone variant H3.3 localization at specific genomic regions

21 January 2018

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Histone H3 variants and their potential role in indexing mammalian genomes: the "H3 barcode hypothesis"

21 January 2018

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Gene expression profiling from formalin-fixed paraffin-embedded tumors of pediatric glioblastoma

21 January 2018

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BRAF-KIAA1549 fusion predicts better clinical outcome in pediatric low-grade astrocytoma.

21 January 2018

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Altered telomeres in tumors with ATRX and DAXX mutations

21 January 2018

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Compromised genomic integrity impedes muscle growth after Atrx inactivation.

21 January 2018

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Duplication of 7q34 is specific to juvenile pilocytic astrocytomas and a hallmark of cerebellar and optic pathway tumours

21 January 2018

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Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas

21 January 2018

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Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

21 January 2018

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Dissecting the genomic complexity underlying medulloblastoma

21 January 2018

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Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas

21 January 2018

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Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma

21 January 2018

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Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

21 January 2018

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K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

21 January 2018

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Brain tumors: from childhood through adolescence into adulthood

21 January 2018

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Pathogenesis of follicular lymphoma

21 January 2018

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Epigenetic memory: H3.3 steps in the groove.

21 January 2018

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Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.

21 January 2018

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Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

21 January 2018

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Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

21 January 2018

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The 2007 WHO classification of tumours of the central nervous system

21 January 2018

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Marking histone H3 variants: how, when and why?

21 January 2018

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IDH mutation impairs histone demethylation and results in a block to cell differentiation

21 January 2018

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Deregulation of H3K27 methylation in cancer

21 January 2018

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Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

21 January 2018

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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

21 January 2018

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Subgroup-specific structural variation across 1,000 medulloblastoma genomes

21 January 2018

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Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

21 January 2018

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Genetic profile of astrocytic and oligodendroglial gliomas

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma

21 January 2018

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Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease

21 January 2018

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BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

21 January 2018

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Expression of p53 and prognosis in children with malignant gliomas.

21 January 2018

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IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group

21 January 2018

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Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas

21 January 2018

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Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches

21 January 2018

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

21 January 2018

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DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs

21 January 2018

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Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

21 January 2018

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Histone variants--ancient wrap artists of the epigenome

21 January 2018

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IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

21 January 2018

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

21 January 2018

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Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

21 January 2018

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Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

21 January 2018

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IDH1 and IDH2 mutations in gliomas

21 January 2018

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Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets.

21 January 2018

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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/BPA.12023

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28 August 2017

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PubMed ID

23432647