Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. (Q53544194)

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English	Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin.	scientific article

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Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin (English)

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hepatocellular carcinoma

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RNA interference

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9

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Yangchao Chen

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Marie C Lin

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Hong Yao

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Hua Wang

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Ai-Qun Zhang

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Jun Yu

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Chee-kin Hui

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George K Lau

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Hsiang-fu Kung

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1 July 2007

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Strategies for retargeted gene delivery using vectors derived from lentiviruses.

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21 January 2018

Hepatocellular carcinoma

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7 January 2021

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Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres

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Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein

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7 January 2021

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Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs

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7 January 2021

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Control of reproduction by Polycomb Group complexes in animals and plants.

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

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7 January 2021

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Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma

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Unlocking the potential of the human genome with RNA interference

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RNA interference-based gene silencing in mice: the development of a novel therapeutical strategy

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Microarrays of lentiviruses for gene function screens in immortalized and primary cells

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EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer

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Knockdown by RNAi-proceed with caution.

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Synthetic shRNAs as potent RNAi triggers.

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

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The role of stathmin in the regulation of the cell cycle

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Proteomic analysis of hepatitis B virus-associated hepatocellular carcinoma: Identification of potential tumor markers.

1 reference

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Stathmin overexpression cooperates with p53 mutation and osteopontin overexpression, and is associated with tumour progression, early recurrence, and poor prognosis in hepatocellular carcinoma.

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7 January 2021

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7 January 2021

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Down-regulation of the stathmin/Op18 and FKBP25 genes following p53 induction.

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7 January 2021

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