Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors (Q38078138)

28 August 2017

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title

Recognition of pathogen-associated nucleic acids by endosomal nucleic acid-sensing toll-like receptors (English)

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28 August 2017

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Xiaobing He

1

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28 August 2017

Huaijie Jia

series ordinal

2

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28 August 2017

Zhizhong Jing

series ordinal

3

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28 August 2017

Dingxiang Liu

series ordinal

4

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28 August 2017

30 January 2013

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Acta Biochimica et Biophysica Sinica

28 August 2017

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28 August 2017

45

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28 August 2017

241-258

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28 August 2017

4

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TLR3 essentially promotes protective class I-restricted memory CD8⁺ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients.

28 August 2017

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12 December 2020

Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

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12 December 2020

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

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12 December 2020

The role of ubiquitin in NF-kappaB regulatory pathways.

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12 December 2020

A mutation of Ikbkg causes immune deficiency without impairing degradation of IkappaB alpha

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12 December 2020

TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification

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12 December 2020

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

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12 December 2020

Understanding TLR9 action in Epstein-Barr virus infection

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12 December 2020

CD14 is a coreceptor of Toll-like receptors 7 and 9.

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12 December 2020

UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii

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12 December 2020

TLR8 deficiency leads to autoimmunity in mice

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12 December 2020

Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells

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12 December 2020

Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections

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12 December 2020

VISA is required for B cell expression of TLR7.

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12 December 2020

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells.

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12 December 2020

Current views of toll-like receptor signaling pathways

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12 December 2020

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

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12 December 2020

Requirement of UNC93B1 reveals a critical role for TLR7 in host resistance to primary infection with Trypanosoma cruzi

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12 December 2020

Autophagy and pattern recognition receptors in innate immunity

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12 December 2020

Inducible SUMO modification of TANK alleviates its repression of TLR7 signalling

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12 December 2020

Toll-like receptors in control of immunological autophagy.

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12 December 2020

SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.

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12 December 2020

A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors

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12 December 2020

TLR13, unlucky, but just for some

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12 December 2020

Cutting edge: TLR13 is a receptor for bacterial RNA

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12 December 2020

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

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12 December 2020

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

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12 December 2020

Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system

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12 December 2020

LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs

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12 December 2020

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking

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12 December 2020

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

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12 December 2020

Comparative analysis of species-specific ligand recognition in Toll-like receptor 8 signaling: a hypothesis

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12 December 2020

Viruses, microRNAs, and host interactions

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12 December 2020

Autophagy in innate recognition of pathogens and adaptive immunity

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12 December 2020

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

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12 December 2020

Cathepsins are required for Toll-like receptor 9 responses

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12 December 2020

Survival of lethal poxvirus infection in mice depends on TLR9, and therapeutic vaccination provides protection

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12 December 2020

Cell type-specific involvement of RIG-I in antiviral response

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12 December 2020

Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway

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12 December 2020

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

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12 December 2020

Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates

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12 December 2020

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

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12 December 2020

Sensing disease and danger: a survey of vertebrate PRRs and their origins

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12 December 2020

Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA

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12 December 2020

A novel Toll-like receptor that recognizes vesicular stomatitis virus

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12 December 2020

Upregulation of the TLR3 pathway by Kaposi's sarcoma-associated herpesvirus during primary infection

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12 December 2020

Detrimental contribution of the Toll-like receptor (TLR)3 to influenza A virus-induced acute pneumonia

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12 December 2020

TLR3 increases disease morbidity and mortality from vaccinia infection

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12 December 2020

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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12 December 2020

TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements

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12 December 2020

Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization

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12 December 2020

Heat shock protein gp96 regulates Toll-like receptor 9 proteolytic processing and conformational stability

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12 December 2020

Antiviral protein Viperin promotes Toll-like receptor 7- and Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells

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12 December 2020

TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA.

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12 December 2020

Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.

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12 December 2020

Cytoplasmic targeting motifs control localization of toll-like receptor 9.

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12 December 2020

MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

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12 December 2020

How location governs toll-like receptor signaling

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12 December 2020

A20 is a negative regulator of IFN regulatory factor 3 signaling.

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12 December 2020

Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.

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12 December 2020

Toll-like receptor 9 signaling activates NF-kappaB through IFN regulatory factor-8/IFN consensus sequence binding protein in dendritic cells

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12 December 2020

Autophagy-dependent viral recognition by plasmacytoid dendritic cells

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12 December 2020

Expression and regulation of toll-like receptors in cerebral endothelial cells.

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12 December 2020

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

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12 December 2020

Essential role for IKKβ in production of type 1 interferons by plasmacytoid dendritic cells.

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12 December 2020

Signature miRNAs involved in the innate immunity of invertebrates

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12 December 2020

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

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12 December 2020

TLR9 is actively recruited to Aspergillus fumigatus phagosomes and requires the N-terminal proteolytic cleavage domain for proper intracellular trafficking

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12 December 2020

UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling

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12 December 2020

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity

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12 December 2020

Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages

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12 December 2020

DNase Sda1 allows invasive M1T1 Group A Streptococcus to prevent TLR9-dependent recognition

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12 December 2020

Regulatory molecules required for nucleotide-sensing Toll-like receptors

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12 December 2020

Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotides

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12 December 2020

TLR8 and TLR7 are involved in the host's immune response to human parechovirus 1.

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12 December 2020

Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells.

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12 December 2020

MicroRNAs in NF-kappaB signaling

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12 December 2020

Autophagy in regulation of Toll-like receptor signaling

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12 December 2020

A cell biological view of Toll-like receptor function: regulation through compartmentalization.

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12 December 2020

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

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12 December 2020

MicroRNA in TLR signaling and endotoxin tolerance.

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12 December 2020

Direct activation of protein kinases by unanchored polyubiquitin chains

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12 December 2020

IFN-α production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and -independent pathways

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12 December 2020

TLR9-dependent activation of dendritic cells by DNA from Leishmania major favors Th1 cell development and the resolution of lesions

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12 December 2020

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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12 December 2020

Antiviral responses induced by the TLR3 pathway

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12 December 2020

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

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12 December 2020

Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta

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12 December 2020

Systematic discovery of TLR signaling components delineates viral-sensing circuits

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12 December 2020

Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger

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12 December 2020

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

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12 December 2020

Autophagy and the immune system

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12 December 2020

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

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12 December 2020

Nucleic acid recognition by the innate immune system

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12 December 2020

Expression of Toll-like receptors in the developing brain

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12 December 2020

Potential subversion of autophagosomal pathway by picornaviruses

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12 December 2020

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

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12 December 2020

DUBA: a deubiquitinase that regulates type I interferon production

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12 December 2020

Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9.

1 reference

12 December 2020

IRAK-M is a negative regulator of Toll-like receptor signaling

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12 December 2020

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

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12 December 2020

Activation of interferon regulatory factor 5 by site specific phosphorylation

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12 December 2020

Transcriptional regulation of the novel Toll-like receptor Tlr13.

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12 December 2020

Negative regulation of signaling by a soluble form of toll-like receptor 9.

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12 December 2020

Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication

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12 December 2020

Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7.

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12 December 2020

Monocyte-Mediated Inhibition of TLR9-Dependent IFN- Induction in Plasmacytoid Dendritic Cells Questions Bacterial DNA as the Active Ingredient of Bacterial Lysates

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12 December 2020

Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors

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12 December 2020

Toll-like receptors and their crosstalk with other innate receptors in infection and immunity

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12 December 2020

Dissecting negative regulation of Toll-like receptor signaling

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12 December 2020

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

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12 December 2020

Accessory molecules for Toll-like receptors and their function

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12 December 2020

Structural biology of the Toll-like receptor family

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12 December 2020

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

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12 December 2020

Identification of an N-terminal recognition site in TLR9 that contributes to CpG-DNA-mediated receptor activation

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12 December 2020

Cofactors required for TLR7- and TLR9-dependent innate immune responses

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12 December 2020

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

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12 December 2020

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent

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12 December 2020

Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.

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12 December 2020

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

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12 December 2020

Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3.

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12 December 2020

Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry

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12 December 2020

Toll-like receptor 9 modulates macrophage antifungal effector function during innate recognition of Candida albicans and Saccharomyces cerevisiae.

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12 December 2020

UNC93B1 mediates innate inflammation and antiviral defense in the liver during acute murine cytomegalovirus infection

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12 December 2020

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

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12 December 2020

Recognition of single-stranded RNA viruses by Toll-like receptor 7

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12 December 2020

[Toll-like receptor 8: the awkward TLR]

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12 December 2020

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

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12 December 2020

Toll-like receptors control autophagy.

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12 December 2020

Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

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12 December 2020

TLR8: the forgotten relative revindicated

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12 December 2020

TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

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12 December 2020

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

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12 December 2020

Human cardiac inflammatory responses triggered by Coxsackie B viruses are mainly Toll-like receptor (TLR) 8-dependent

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12 December 2020

Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection

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12 December 2020

TLR3 deletion limits mortality and disease severity due to Phlebovirus infection.

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12 December 2020

TLR signaling is required for Salmonella typhimurium virulence

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12 December 2020

Double-stranded RNAs from the Helminth ParasiteSchistosomaActivate TLR3 in Dendritic Cells

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12 December 2020

Dengue virus ensures its fusion in late endosomes using compartment-specific lipids

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12 December 2020

Toll-like receptor 3 promotes cross-priming to virus-infected cells.

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12 December 2020

Mitochondrial ubiquitin ligase MARCH5 promotes TLR7 signaling by attenuating TANK action

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12 December 2020

TLR7 and TLR9 in SLE: when sensing self goes wrong

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12 December 2020

Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling

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12 December 2020

NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.

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12 December 2020

Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

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12 December 2020

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

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12 December 2020

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

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12 December 2020

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

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12 December 2020

Regulation of innate immune responses by autophagy-related proteins

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12 December 2020

TLR9 contributes to antiviral immunity during gammaherpesvirus infection

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12 December 2020

Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon

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12 December 2020

The battle between virus and host: modulation of Toll-like receptor signaling pathways by virus infection

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12 December 2020

CD2AP/SHIP1 complex positively regulates plasmacytoid dendritic cell receptor signaling by inhibiting the E3 ubiquitin ligase Cbl

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12 December 2020

Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3

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12 December 2020

Autophagosome supports coxsackievirus B3 replication in host cells

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12 December 2020

RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection

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12 December 2020

Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone

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12 December 2020

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

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12 December 2020

Pattern recognition receptors and the innate immune response to viral infection

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12 December 2020

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.

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12 December 2020

Involvement of the Toll-like receptor 9 signaling pathway in the induction of innate immunity by baculovirus

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12 December 2020

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon

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12 December 2020

Regulation of interleukin-1- and lipopolysaccharide-induced NF-kappaB activation by alternative splicing of MyD88

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12 December 2020

PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells.

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12 December 2020

Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses

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12 December 2020

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

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12 December 2020

Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition

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12 December 2020

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

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12 December 2020

Innate immune effectors in mycobacterial infection

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12 December 2020

Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

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12 December 2020

A five-amino-acid motif in the undefined region of the TLR8 ectodomain is required for species-specific ligand recognition.

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12 December 2020

Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors

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12 December 2020

Modification of cellular autophagy protein LC3 by poliovirus

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12 December 2020

Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA

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12 December 2020

Scavenger receptors in human airway epithelial cells: role in response to double-stranded RNA

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12 December 2020

Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury

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12 December 2020

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes

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12 December 2020

HHV-6B induces IFN-lambda1 responses in cord plasmacytoid dendritic cells through TLR9

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12 December 2020

Does Toll-like receptor 3 play a biological role in virus infections?

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12 December 2020

Immune receptors involved in Streptococcus suis recognition by dendritic cells

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12 December 2020

MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo

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12 December 2020

Molecular cloning and functional characterization of porcine toll-like receptor 7 involved in recognition of single-stranded RNA virus/ssRNA.

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12 December 2020

TLR3 deficiency in patients with herpes simplex encephalitis

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12 December 2020

Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.

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12 December 2020

TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis

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12 December 2020

Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection

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12 December 2020

Recognition of yeast nucleic acids triggers a host-protective type I interferon response

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12 December 2020

MicroRNAs: the fine-tuners of Toll-like receptor signalling

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12 December 2020

Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.

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12 December 2020

Identifiers

DOI

10.1093/ABBS/GMS122

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28 August 2017

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