Advances in targeting voltage-gated sodium channels with small molecules (Q38040330)

27 August 2017

Advances in targeting voltage-gated sodium channels with small molecules (English)

1 reference

27 August 2017

Antonio Nardi

1

1 reference

27 August 2017

Nils Damann

series ordinal

2

1 reference

27 August 2017

Torsten Hertrampf

series ordinal

3

1 reference

27 August 2017

Achim Kless

series ordinal

4

1 reference

27 August 2017

language of work or name

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4 September 2012

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27 August 2017

1 reference

27 August 2017

7

1 reference

27 August 2017

1712-1740

1 reference

27 August 2017

10

1 reference

Voltage-gated sodium channels as therapeutic targets

27 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac ion channel gene mutations in Greek long QT syndrome patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac sodium channel Na(v)1.5 and interacting proteins: Physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Clinical impact of genetic studies in lethal inherited cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac sodium channels and inherited electrophysiologic disorders: a pharmacogenetic overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel SCN1A and epilepsy: mutations and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel mutations in epilepsy and other neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Neuronal sodium-channel alpha1-subunit mutations in generalized epilepsy with febrile seizures plus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Two novel mutations of SCN9A (Nav1.7) are associated with partial congenital insensitivity to pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Congenital insensitivity to pain: novel SCN9A missense and in-frame deletion mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A nonsense mutation in the SCN9A gene in congenital insensitivity to pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Severe case and literature review of primary erythromelalgia: novel SCN9A gene mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Pain disorders and erythromelalgia caused by voltage-gated sodium channel mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Deletion mutation of sodium channel Na(V)1.7 in inherited erythromelalgia: enhanced slow inactivation modulates dorsal root ganglion neuron hyperexcitability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Paroxysmal extreme pain disorder (previously familial rectal pain syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structural trends among second-generation voltage-gated sodium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage-gated sodium channel blockers for the treatment of chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Blocking sodium channels to treat neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Recent advances in the medicinal chemistry of sodium channel blockers and their therapeutic potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Targeting voltage-gated sodium channels for pain therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Subtype-selective sodium channel blockers promise a new era of pain research

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Blockers of voltage-gated sodium channels for the treatment of central nervous system diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel blockers as therapeutic target for treating epilepsy: recent updates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Isoform-selective voltage-gated Na(+) channel modulators as next-generation analgesics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel beta subunits: anything but auxiliary

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The role of sodium channels in cell adhesion

21 January 2018

2 references

https://api.crossref.org/works/10.1002%2FCMDC.201200298

21 January 2018

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Sodium channel auxiliary subunits

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Restoration of inactivation and block of open sodium channels by an inactivation gate peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Kinetic analysis of block of open sodium channels by a peptide containing the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The tetrodotoxin binding site is within the outer vestibule of the sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Specificity for block by saxitoxin and divalent cations at a residue which determines sensitivity of sodium channel subtypes to guanidinium toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Primary structure and functional expression of the beta 1 subunit of the rat brain sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage-gated ion channels and gating modifier toxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Epithelial Na Channels: Function and Diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

SCN9A mutations define primary erythermalgia as a neuropathic disorder of voltage gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Erythromelalgia: an endothelial disorder responsive to sodium nitroprusside

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Evolution and diversity of mammalian sodium channel genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Three types of sodium channels in adult rat dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Characterization of TTX-sensitive and TTX-resistant sodium currents in small cells from adult rat dorsal root ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ionic currents in the somatic membrane of rat dorsal root ganglion neurons—I. Sodium currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A tetrodotoxin-resistant voltage-gated sodium channel expressed by sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Spinal sensory neurons express multiple sodium channel alpha-subunit mRNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Two tetrodotoxin-resistant sodium channels in human dorsal root ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

NaV1.1 channels and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Navigating the channels and beyond: unravelling the genetics of the epilepsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The genetic basis of Brugada syndrome: a mutation update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel (dys)function and cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac sodium channelopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cardiac ion channels in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Familial pain syndromes from mutations of the NaV1.7 sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Erythermalgia: molecular basis for an inherited pain syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

An SCN9A channelopathy causes congenital inability to experience pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Neurobiology: a channel sets the gain on pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Exploring the role of nociceptor-specific sodium channels in pain transmission using Nav1.8 and Nav1.9 knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Potent analgesic effects of GDNF in neuropathic pain states.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The pharmacology of voltage-gated sodium channels in sensory neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Mechanisms of Action of Antiepileptic Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular model of anticonvulsant drug binding to the voltage-gated sodium channel inner pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A randomized, double-blind, placebo-controlled, two-period, crossover, pilot trial of lamotrigine in patients with central pain due to multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Double-blind, placebo-controlled trial of lamotrigine in combination with other medications for neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Effects of antiepileptic drugs on pentylenetetrazole-induced epileptiform activity in the in vitro hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Mechanisms of sodium channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel inactivation: molecular determinants and modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Effective topical anesthetic agents and techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Subtype-selective targeting of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Tetrodotoxin: a brief history

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The crystal structure of a voltage-gated sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Targeting voltage-gated sodium channels for treating neuropathic and inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

C-fiber spontaneous discharge evoked by chronic inflammation is suppressed by a long-term infusion of lidocaine yielding nanogram per milliliter plasma levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The relationship between sodium channel inhibition and anticonvulsant activity in a model of generalised seizure in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

On the relationship between block of the cardiac Na⁺ channel and drug-induced prolongation of the QRS complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The 'overly-sensitive' heart: sodium channel block and QRS interval prolongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure and function of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Slow inactivation of the sodium conductance in squid giant axons. Pronase resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Properties of slow, cumulative sodium channel inactivation in rat hippocampal CA1 pyramidal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Dynamic rearrangement of the outer mouth of a K+ channel during gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Spinal and supraspinal contributions to central sensitization in peripheral neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The glycinergic control of spinal pain processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Modulation of voltage-dependent sodium channels by the delta-agonist SNC80 in acutely isolated rat hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Slow inactivation in voltage-gated sodium channels: molecular substrates and contributions to channelopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Fast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Lacosamide: a review of preclinical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A novel slow-inactivation-specific ion channel modulator attenuates neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel inhibitor drug discovery using automated high throughput electrophysiology platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Automated planar electrode electrophysiology in drug discovery: examples of the use of QPatch in basic characterization and high content screening on Na(v), K(Ca)2.3, and K(v)11.1 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Validation of a patch clamp screening protocol that simultaneously measures compound activity in multiple states of the voltage-gated sodium channel Nav1.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Inhibition of Na(+) current by imipramine and related compounds: different binding kinetics as an inactivation stabilizer and as an open channel blocker

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Characterization of lamotrigine inhibition of Na+ channels in rat hippocampal neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Extrapore residues of the S5-S6 loop of domain 2 of the voltage-gated skeletal muscle sodium channel (rSkM1) contribute to the mu-conotoxin GIIIA binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Conotoxin modulation of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Two novel sodium channel inhibitors from Heriaeus melloteei spider venom differentially interacting with mammalian channel's isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Grayanotoxin, veratrine, and tetrodotoxin-sensitive sodium pathways in the Schwann cell membrane of squid nerve fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structural determinants for the action of grayanotoxin in D1 S4-S5 and D4 S4-S5 intracellular linkers of sodium channel alpha-subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Na(v)1.4 sodium channel as revealed by improved estimation of toxin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Veratridine block of rat skeletal muscle Nav1.4 sodium channels in the inner vestibule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Modified gating behaviour of aconitine treated single sodium channels from adult cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structural model reveals key interactions in the assembly of the pregnane X receptor/corepressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

State-dependent access to the batrachotoxin receptor on the sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The batrachotoxin receptor on the voltage-gated sodium channel is guarded by the channel activation gate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Interaction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Antillatoxin is a sodium channel activator that displays unique efficacy in heterologously expressed rNav1.2, rNav1.4 and rNav1.5 α subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Antillatoxin, a novel lipopeptide, enhances neurite outgrowth in immature cerebrocortical neurons through activation of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Antillatoxin is a marine cyanobacterial toxin that potently activates voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channel activators: model of binding inside the pore and a possible mechanism of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Neurotoxins and their binding areas on voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Identification of new batrachotoxin-sensing residues in segment IIIS6 of the sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Point-mutations related to the loss of batrachotoxin binding abolish the grayanotoxin effect in Na(+) channel isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Isolation and pharmacological characterisation of delta-atracotoxin-Hv1b, a vertebrate-selective sodium channel toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

First chemical synthesis of a scorpion alpha-toxin affecting sodium channels: the Aah I toxin of Androctonus australis hector

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage-dependent open-state inactivation of cardiac sodium channels: gating current studies with Anthopleurin-A toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Control of thallium and sodium fluxes in isolated adult rat heart cells by anthopleurin-A, verapamil and magnesium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cellular lithium uptake as a probe of sodium channels in the rat heart: Modulation of lithium uptake by tetrodotoxin, verapamil, anthopleurin-A, isoproterenol and external stimulation*

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Localization of the receptor site for alpha-scorpion toxins by antibody mapping: implications for sodium channel topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Targeting voltage sensors in sodium channels with spider toxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Jingzhaotoxin-III, a novel spider toxin inhibiting activation of voltage-gated sodium channel in rat cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

ProTx-I and ProTx-II: gating modifiers of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Insect-selective spider toxins targeting voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Distinct primary structures of the major peptide toxins from the venom of the spider Macrothele gigas that bind to sites 3 and 4 in the sodium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ciguatoxins and brevetoxins, neurotoxic polyether compounds active on sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ciguatoxin-induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Effects of delta-conotoxins PVIA and SVIE on sodium channels in the amphibian sympathetic nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular interaction of delta-conotoxins with voltage-gated sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

State-Dependent Modification of Voltage-Gated Sodium Channels by Pyrethroids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Voltage-gated sodium channels as primary targets of diverse lipid-soluble neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Mechanism of local anesthetic drug action on voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular determinants of voltage-dependent gating and binding of pore-blocking drugs in transmembrane segment IIIS6 of the Na(+) channel alpha subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Automated electrophysiology in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

State-dependent compound inhibition of Nav1.2 sodium channels using the FLIPR Vm dye: on-target and off-target effects of diverse pharmacological agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Cellular Fluorescent Indicators and Voltage/Ion Probe Reader (VIPR TM ): Tools for Ion Channel and Receptor Drug Discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Characterization of voltage-gated sodium-channel blockers by electrical stimulation and fluorescence detection of membrane potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ion-channel assay technologies: quo vadis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Characterization of a new class of potent inhibitors of the voltage-gated sodium channel Nav1.7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery of a novel class of isoxazoline voltage gated sodium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery of isoxazole voltage gated sodium channel blockers for treatment of chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structural determinants of drugs acting on the Nav1.8 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery and hit-to-lead optimization of pyrrolopyrimidines as potent, state-dependent Na(v)1.7 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery and optimization of aminopyrimidinones as potent and state-dependent Nav1.7 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Inhibition of tetrodotoxin (TTX)-resistant and TTX-sensitive neuronal Na(+) channels by the secretolytic ambroxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ambroxol, a Nav1.8-preferring Na(+) channel blocker, effectively suppresses pain symptoms in animal models of chronic, neuropathic and inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Antinociceptive effect of ambroxol in rats with neuropathic spinal cord injury pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The differential effect of intrathecal Nav1.8 blockers on the induction and maintenance of capsaicin- and peripheral ischemia-induced mechanical allodynia and thermal hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channels and nociception: recent concepts and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channels in normal and pathological pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Nav1.9 channel contributes to mechanical and heat pain hypersensitivity induced by subacute and chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The roles of sodium channels in nociception: implications for mechanisms of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The role of sodium channels in neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Pharmacological properties of neuronal TTX-resistant sodium channels and the role of a critical serine pore residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Treatment of Na(v)1.7-mediated pain in inherited erythromelalgia using a novel sodium channel blocker

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular targets for antiepileptic drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The neurobiology of antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Resurgent currents turn painfully exciting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

A peripherally acting Na(v)1.7 sodium channel blocker reverses hyperalgesia and allodynia on rat models of inflammatory and neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Topical lidocaine gel relieves postherpetic neuralgia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Tetrodotoxin (TTX) as a therapeutic agent for pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Beta-scorpion toxin effects suggest electrostatic interactions in domain II of voltage-dependent sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure and function of the voltage sensor of sodium channels probed by a beta-scorpion toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The insecticidal potential of scorpion beta-toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure-function map of the receptor site for β-scorpion toxins in domain II of voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

How membrane proteins sense voltage

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Persistent sodium current in mammalian central neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Primary structure and expression of a sodium channel characteristic of denervated and immature rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Kinetic properties of single sodium channels in rat heart and rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Electrophysiological properties of in vitro Purkinje cell somata in mammalian cerebellar slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Persistent Na-channels: origin and function. A review

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Gabapentin selectively reduces persistent sodium current in injured type-A dorsal root ganglion neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Recent developments regarding voltage-gated sodium channel blockers for the treatment of inherited and acquired neuropathic pain syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Riluzole, neuroprotection and amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Blockade of persistent sodium currents contributes to the riluzole-induced inhibition of spontaneous activity and oscillations in injured DRG neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ranolazine: new approach for the treatment of stable angina pectoris

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Block of tetrodotoxin-sensitive, Na(V)1.7 and tetrodotoxin-resistant, Na(V)1.8, Na+ channels by ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

The cardiac persistent sodium current: an appealing therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ranolazine attenuates behavioral signs of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ranolazine attenuation of CFA-induced mechanical hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Control of transient, resurgent, and persistent current by open-channel block by Na channel beta4 in cultured cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Inhibition of Navβ4 peptide-mediated resurgent sodium currents in Nav1.7 channels by carbamazepine, riluzole, and anandamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ranolazine selectively blocks persistent current evoked by epilepsy-associated Naν1.1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Y1767C, a novel SCN5A mutation, induces a persistent Na+ current and potentiates ranolazine inhibition of Nav1.5 channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Selective inhibition of persistent sodium current by F 15845 prevents ischaemia-induced arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium channels: ionic model of slow inactivation and state-dependent drug binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure and function of the cardiac sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Synthesis and characterization of huwentoxin-IV, a neurotoxin inhibiting central neuronal sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Isolation and characterization of hainantoxin-IV, a novel antagonist of tetrodotoxin-sensitive sodium channels from the Chinese bird spider Selenocosmia hainana

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Inhibition of neuronal tetrodotoxin-sensitive Na+ channels by two spider toxins: hainantoxin-III and hainantoxin-IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Architecture and pore block of eukaryotic voltage-gated sodium channels in view of NavAb bacterial sodium channel structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Elucidation of the molecular basis of selective recognition uncovers the interaction site for the core domain of scorpion alpha-toxins on sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Function and role of voltage-gated sodium channel NaV1.7 expressed in aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Block of Nav1.8 by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Recent advances in adjunctive therapy for epilepsy: focus on sodium channel blockers as third-generation antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Discovery of XEN907, a spirooxindole blocker of NaV1.7 for the treatment of pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

F 15845, a new blocker of the persistent sodium current prevents consequences of hypoxia in rat femoral artery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Myocardial protection by F 15845, a persistent sodium current blocker, in an ischemia-reperfusion model in the pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

Sodium late current blockers in ischemia reperfusion: is the bullet magic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

China must provide education on HIV

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

[Congenital insensitivity to pain]

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Cellular and molecular biology of voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Molecular kinetics of voltage-dependent Na+ channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Structure and functional expression of a new member of the tetrodotoxin-sensitive voltage-activated sodium channel family from human neuroendocrine cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Differential properties of tetrodotoxin-sensitive and tetrodotoxin- resistant sodium channels in rat dorsal root ganglion neurons

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Genetics of Brugada syndrome

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Molecular genetics of long QT syndrome

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Differential regulation of three sodium channel messenger RNAs in the rat central nervous system during development.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Sodium channels as molecular targets for antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

On site of action of grayanotoxin in domain 4 segment 6 of rat skeletal muscle sodium channel.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Alpha-scorpion toxins binding on rat brain and insect sodium channels reveal divergent allosteric modulations by brevetoxin and veratridine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Differences in the binding sites of two site-3 sodium channel toxins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Substituted biaryl oxazoles, imidazoles, and thiazoles as sodium channel blockers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Substituted biaryl pyrazoles as sodium channel blockers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Imidazopyridines: A novel class of hNav1.7 channel blockers

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Painful research: identification of a small-molecule inhibitor that selectively targets Nav1.8 sodium channels

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

The discovery of aminopyrazines as novel, potent Nav1.7 antagonists: Hit-to-lead identification and SAR

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Persistent pain: the contribution of Na(V)1.9.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Block of peripheral nerve sodium channels selectively inhibits features of neuropathic pain in rats.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Different voltage dependence of transient and persistent Na+ currents is compatible with modal-gating hypothesis for sodium channels.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Potent modulation of the voltage-gated sodium channel Nav1.7 by OD1, a toxin from the scorpion Odonthobuthus doriae.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Crystal structure of a voltage-gated sodium channel in two potentially inactivated states

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Phenyl isoxazole voltage-gated sodium channel blockers: Structure and activity relationship

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Use of amino acid composition to predict ligand-binding sites

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201200298

7 January 2021

Identifiers

DOI

10.1002/CMDC.201200298

1 reference

27 August 2017

1 reference