Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines (Q38032881)

27 August 2017

Liposomes containing lipid A: an effective, safe, generic adjuvant system for synthetic vaccines (English)

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27 August 2017

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Gary R Matyas

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Mangala Rao

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2

object named as

Mangala Rao

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27 August 2017

Carl R Alving

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PubMed ID

22873129

27 August 2017

Nicholas J Steers

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3

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PubMed ID

22873129

27 August 2017

Alexander V Mayorov

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27 August 2017

1 June 2012

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Expert Review of Vaccines

27 August 2017

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27 August 2017

11

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27 August 2017

733-744

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27 August 2017

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Vaccine adjuvants: putting innate immunity to work

27 August 2017

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First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children

21 January 2018

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Safety and efficacy of the RTS, S/AS01 E candidate malaria vaccine given with expanded-programme-on-immunisation vaccines: 19 month follow-up of a randomised, open-label, phase 2 trial

21 January 2018

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Moving candidate vaccines into development from research: lessons from HIV.

21 January 2018

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Vaccine adjuvants: a priority for vaccine research.

21 January 2018

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A 2020 vision for vaccines against HIV, tuberculosis and malaria.

21 January 2018

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The perfect mix: recent progress in adjuvant research

21 January 2018

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The RTS,S malaria vaccine

21 January 2018

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Combination adjuvants: the next generation of adjuvants?

21 January 2018

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Recent clinical experience with vaccines using MPL- and QS-21-containing adjuvant systems

21 January 2018

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Unmet needs in modern vaccinology: adjuvants to improve the immune response

21 January 2018

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Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens

21 January 2018

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Vaccine adjuvants: scientific challenges and strategic initiatives

21 January 2018

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Patent data mining: a tool for accelerating HIV vaccine innovation

21 January 2018

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From "banghasomes" to liposomes: a memoir of Alec Bangham, 1921-2010.

21 January 2018

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Liposome technology for industrial purposes

21 January 2018

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Structure of bacterial lipopolysaccharides

21 January 2018

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Innate immune sensing and its roots: the story of endotoxin

21 January 2018

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Lipid A and liposomes containing lipid A as antigens and adjuvants

21 January 2018

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Lipopolysaccharide: Biosynthetic pathway and structure modification

21 January 2018

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Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.

21 January 2018

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Key structures of bacterial peptidoglycan and lipopolysaccharide triggering the innate immune system of higher animals: chemical synthesis and functional studies

21 January 2018

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3-O-Desacyl monophosphoryl lipid A derivatives: synthesis and immunostimulant activities

21 January 2018

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Structural requirements of lipid A for endotoxicity and other biological activities

21 January 2018

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A synthetic adjuvant to enhance and expand immune responses to influenza vaccines

21 January 2018

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Evaluation of the safety and immunogenicity in rhesus monkeys of a recombinant malaria vaccine for Plasmodium vivax with a synthetic Toll-like receptor 4 agonist formulated in an emulsion

21 January 2018

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GLA-SE, a synthetic toll-like receptor 4 agonist, enhances T-cell responses to influenza vaccine in older adults

21 January 2018

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Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant

21 January 2018

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Immunity in response to particulate antigen-delivery systems

21 January 2018

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Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

21 January 2018

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Immunology of TLR-independent vaccine adjuvants

21 January 2018

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Antigen depot is not required for alum adjuvanticity

21 January 2018

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Liposomes based on dimethyldioctadecylammonium promote a depot effect and enhance immunogenicity of soluble antigen

21 January 2018

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Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41.

21 January 2018

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Highly effective generic adjuvant systems for orphan or poverty-related vaccines

21 January 2018

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Safety, immunogenicity, and efficacy of Plasmodium falciparum repeatless circumsporozoite protein vaccine encapsulated in liposomes

21 January 2018

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Liposomal malaria vaccine in humans: a safe and potent adjuvant strategy

21 January 2018

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Liposomes as carriers of antigens and adjuvants

21 January 2018

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Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes

21 January 2018

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Human dendritic cells and macrophages exhibit different intracellular processing pathways for soluble and liposome-encapsulated antigens

21 January 2018

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Liposome-coupled antigens are internalized by antigen-presenting cells via pinocytosis and cross-presented to CD8 T cells

21 January 2018

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Functional microtubules are required for antigen processing by macrophages and dendritic cells.

21 January 2018

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Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells. mangala.rao@na.amedd.army.mil

21 January 2018

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The proteasome and MHC class I antigen processing

21 January 2018

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Structural and functional properties of proteasome activator PA28.

21 January 2018

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The role of the proteasome activator PA28 in MHC class I antigen processing

21 January 2018

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Modulation of immunoproteasome subunits by liposomal lipid A.

21 January 2018

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Liposome-encapsulated HIV-1 Gag p24 containing lipid A induces effector CD4+ T-cells, memory CD8+ T-cells, and pro-inflammatory cytokines.

21 January 2018

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Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions

21 January 2018

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Dendritic-cell interactions with HIV: infection and viral dissemination

21 January 2018

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Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step study

21 January 2018

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Strong HIV-specific CD4+ and CD8+ T-lymphocyte proliferative responses in healthy individuals immunized with an HIV-1 DNA vaccine and boosted with recombinant modified vaccinia virus ankara expressing HIV-1 genes

21 January 2018

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A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

21 January 2018

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Human immunodeficiency virus type 1 Gag p24 alters the composition of immunoproteasomes and affects antigen presentation

21 January 2018

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Cell type-specific proteasomal processing of HIV-1 Gag-p24 results in an altered epitope repertoire

21 January 2018

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Advances in the design and delivery of peptide subunit vaccines with a focus on toll-like receptor agonists

21 January 2018

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Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

21 January 2018

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The expression of endotoxic activity in the Limulus test as compared to cytokine production in immune cells

21 January 2018

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Phase-I study of intravenous modified lipid A.

21 January 2018

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Immunogenicity of liposomal malaria sporozoite antigen in monkeys: adjuvant effects of aluminium hydroxide and non-pyrogenic liposomal lipid A.

21 January 2018

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Physicochemical characterization and biological activity of synthetic TLR4 agonist formulations

21 January 2018

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Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers.

21 January 2018

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Inhibition of HIV-1 infection of peripheral blood mononuclear cells by a monoclonal antibody that binds to phosphoinositides and induces secretion of β-chemokines

21 January 2018

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Neutralizing antibodies induced by liposomal HIV-1 glycoprotein 41 peptide simultaneously bind to both the 2F5 or 4E10 epitope and lipid epitopes

21 January 2018

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The effect of cholesterol in a liposomal Muc1 vaccine

21 January 2018

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A liposome-based therapeutic vaccine against beta -amyloid plaques on the pancreas of transgenic NORBA mice

21 January 2018

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Conjugation of ligands to the surface of preformed liposomes by click chemistry

21 January 2018

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Liposomes as carriers of peptide antigens: induction of antibodies and cytotoxic T lymphocytes to conjugated and unconjugated peptides

21 January 2018

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Protein misfolding, functional amyloid, and human disease

21 January 2018

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

21 January 2018

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Developing novel immunogens for a safe and effective Alzheimer's disease vaccine

21 January 2018

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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

21 January 2018

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Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

21 January 2018

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Sequence-independent control of peptide conformation in liposomal vaccines for targeting protein misfolding diseases

21 January 2018

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Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS,S/AS01B and RTS,S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of protection

21 January 2018

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HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane

21 January 2018

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Selection of potent immunological adjuvants for vaccine construction

21 January 2018

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Design and selection of vaccine adjuvants: animal models and human trials

21 January 2018

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Incorporation of the TLR4 Agonist Monophosphoryl Lipid A Into the Bilayer of DDA/TDB Liposomes: Physico-Chemical Characterization and Induction of CD8+ T-Cell Responses In Vivo

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/ERV.12.35

1 reference

27 August 2017

1 reference

PubMed ID

22873129