Sulfonamides: a patent review (2008 - 2012). (Q38018632)

27 August 2017

title

Sulfonamides: a patent review (2008 - 2012). (English)

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27 August 2017

2

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27 August 2017

Fabrizio Carta

1

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Claudiu T Supuran

series ordinal

3

object named as

Claudiu T Supuran

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27 August 2017

language of work or name

English

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publication date

15 June 2012

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Expert Opinion on Therapeutic Patents

27 August 2017

published in

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27 August 2017

volume

22

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27 August 2017

issue

7

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27 August 2017

page(s)

747-758

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Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

27 August 2017

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Carbonic anhydrase inhibitors

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Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets

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Nitric oxide-donating carbonic anhydrase inhibitors for the treatment of open-angle glaucoma

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Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action

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Inhibition and binding studies of carbonic anhydrase isozymes I, II and IX with benzimidazo[1,2-c][1,2,3]thiadiazole-7-sulphonamides

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Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells

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Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies

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Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

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Imaging of CA IX with fluorescent labelled sulfonamides distinguishes hypoxic and (re)-oxygenated cells in a xenograft tumour model

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In vivo targeting of tumor-associated carbonic anhydrases using acetazolamide derivatives

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21 January 2018

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Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

21 January 2018

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Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target

21 January 2018

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Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial

21 January 2018

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Phase I Dose-Finding Study of Pazopanib in Hepatocellular Carcinoma: Evaluation of Early Efficacy, Pharmacokinetics, and Pharmacodynamics

21 January 2018

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21 January 2018

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21 January 2018

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Carbonic Anhydrase Inhibitors: X-ray and Molecular Modeling Study for the Interaction of a Fluorescent Antitumor Sulfonamide with Isozyme II and IX

21 January 2018

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Carbonic Anhydrase Inhibitors. Synthesis of Water-Soluble, Topically Effective, Intraocular Pressure-Lowering Aromatic/Heterocyclic Sulfonamides Containing Cationic or Anionic Moieties: Is the Tail More Important than the Ring?1

21 January 2018

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Carbonic Anhydrase Inhibitors: Perfluoroalkyl/Aryl-Substituted Derivatives of Aromatic/Heterocyclic Sulfonamides as Topical Intraocular Pressure-Lowering Agents with Prolonged Duration of Action

21 January 2018

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Carbonic anhydrase inhibitors — Part 53. Synthesis of substituted-pyridinium derivatives of aromatic sulfonamides: The first non-polymeric membrane-impermeable inhibitors with selectivity for isozyme IV

21 January 2018

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Protein tyrosine kinase inhibitors as anticancer agents

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10.1517/13543776.2012.698264

21 January 2018

Identifiers

DOI

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27 August 2017

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