The development of effective biomarkers for Alzheimer's disease: a review (Q38016800)

27 August 2017

The development of effective biomarkers for Alzheimer's disease: a review (English)

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27 August 2017

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Stephen Todd

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Bernadette McGuinness

4

object named as

Bernadette McGuinness

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27 August 2017

Mark S Henry

1

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27 August 2017

Anthony P Passmore

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27 August 2017

David Craig

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27 August 2017

Janet A Johnston

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27 August 2017

language of work or name

English

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publication date

4 June 2012

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International Journal of Geriatric Psychiatry

27 August 2017

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27 August 2017

28

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27 August 2017

4

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27 August 2017

331-340

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Inflammation and Alzheimer's disease

27 August 2017

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Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease.

21 January 2018

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Rethinking Alzheimer's disease therapy: are mitochondria the key?

21 January 2018

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Platelet APP isoform ratios correlate with declining cognition in AD.

21 January 2018

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Alzheimer disease: New light on an old CLU.

21 January 2018

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CSF markers for incipient Alzheimer's disease

21 January 2018

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The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease.

21 January 2018

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Platelet amyloid precursor protein abnormalities in mild cognitive impairment predict conversion to dementia of Alzheimer type: a 2-year follow-up study.

21 January 2018

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Pre-clinical diagnosis of Alzheimer disease combining platelet amyloid precursor protein ratio and rCBF spect analysis.

21 January 2018

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Role of phenylalanine 20 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

21 January 2018

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Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease

21 January 2018

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Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio.

21 January 2018

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CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease.

21 January 2018

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CSF tau protein phosphorylated at threonine 231 correlates with cognitive decline in MCI subjects

21 January 2018

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Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231.

21 January 2018

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In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid beta-peptide of APP.

21 January 2018

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Maximizing the Alzheimer's Disease Neuroimaging Initiative II.

21 January 2018

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Platelet APP, ADAM 10 and BACE alterations in the early stages of Alzheimer disease

21 January 2018

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Medial temporal lobe function and structure in mild cognitive impairment

21 January 2018

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Serum inflammatory proteins and cognitive decline in older persons.

21 January 2018

1 reference

Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease

21 January 2018

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Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

21 January 2018

1 reference

Inflammatory proteins in plasma and the risk of dementia: the rotterdam study

21 January 2018

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Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets

21 January 2018

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Blood-based biomarkers of microvascular pathology in Alzheimer's disease

21 January 2018

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Low cerebrospinal-fluid concentrations of soluble amyloid beta-protein precursor in hereditary Alzheimer's disease

21 January 2018

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Cerebrospinal fluid tau, A beta, and phosphorylated tau protein for the diagnosis of Alzheimer's disease.

21 January 2018

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PET imaging of amyloid deposition in patients with mild cognitive impairment.

21 January 2018

1 reference

Clinical biomarkers in drug discovery and development

21 January 2018

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Biological markers for therapeutic trials in Alzheimer's disease. Proceedings of the biological markers working group; NIA initiative on neuroimaging in Alzheimer's disease

21 January 2018

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Platelet alpha- and beta- secretase activities are not significantly affected by dementia or mild cognitive impairment in Swedish patients.

21 January 2018

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Longitudinal study of the early neuropsychological and cerebral metabolic changes in dementia of the Alzheimer type.

21 January 2018

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Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease.

21 January 2018

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Core candidate neurochemical and imaging biomarkers of Alzheimer's disease

21 January 2018

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Core biological marker candidates of Alzheimer's disease - perspectives for diagnosis, prediction of outcome and reflection of biological activity

21 January 2018

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Biological markers of amyloid beta-related mechanisms in Alzheimer's disease

21 January 2018

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Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease

21 January 2018

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Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives

21 January 2018

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Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

21 January 2018

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The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

21 January 2018

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

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CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment.

21 January 2018

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Improved discrimination of AD patients using beta-amyloid(1-42) and tau levels in CSF.

21 January 2018

1 reference

Proteome-based plasma biomarkers for Alzheimer's disease

21 January 2018

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Biomarkers of Alzheimer disease in plasma

21 January 2018

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Cerebrospinal fluid TAU protein and amyloid beta42 in mild cognitive impairment: prediction of progression to Alzheimer's disease and correlation with the neuropsychological examination.

21 January 2018

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Introduction to the recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

21 January 2018

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Rate of medial temporal lobe atrophy in typical aging and Alzheimer's disease

21 January 2018

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Rates of hippocampal atrophy correlate with change in clinical status in aging and AD.

21 January 2018

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11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

21 January 2018

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Amyloid beta-protein deposition in tissues other than brain in Alzheimer's disease

21 January 2018

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Platelet beta-secretase activity is increased in Alzheimer's disease.

21 January 2018

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1H magnetic resonance spectroscopy in dementia

21 January 2018

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Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer's disease?

21 January 2018

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Alzheimer's disease and its focal variants

21 January 2018

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Hippocampus in Alzheimer's disease: a 3-year follow-up MRI study.

21 January 2018

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Identification of a blood-based biomarker panel for classification of Alzheimer's disease

21 January 2018

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The molecular bases of Alzheimer's disease and other neurodegenerative disorders

21 January 2018

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High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age.

21 January 2018

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CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

21 January 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

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Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease.

21 January 2018

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Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

21 January 2018

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Hippocampal activation in adults with mild cognitive impairment predicts subsequent cognitive decline

21 January 2018

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Rate of progression of mild cognitive impairment to dementia--meta-analysis of 41 robust inception cohort studies.

21 January 2018

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Predictors of conversion to dementia of probable Alzheimer type in patients with mild cognitive impairment

21 January 2018

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N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology

21 January 2018

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Early-stage and preclinical Alzheimer disease.

21 January 2018

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Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI).

21 January 2018

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Abnormalities in the pattern of platelet amyloid precursor protein forms in patients with mild cognitive impairment and Alzheimer disease.

21 January 2018

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Fluorodeoxyglucose-positron emission tomography in the differential diagnosis of early-onset dementia: a prospective, community-based study

21 January 2018

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Neuropathology of Alzheimer's disease

21 January 2018

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Age and apolipoprotein E*4 allele effects on cerebrospinal fluid beta-amyloid 42 in adults with normal cognition.

21 January 2018

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Use of Alzheimer disease biomarkers: potentially yes for clinical trials but not yet for clinical practice

21 January 2018

1 reference

PET imaging of brain amyloid in dementia: a review

21 January 2018

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Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

21 January 2018

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Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening

21 January 2018

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Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

21 January 2018

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Altered amyloid protein processing in platelets of patients with Alzheimer disease.

21 January 2018

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A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain

21 January 2018

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Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study.

21 January 2018

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Plasma clusterin and the risk of Alzheimer disease

21 January 2018

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Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease

21 January 2018

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Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

21 January 2018

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Decreased CSF-beta-amyloid 42 in Alzheimer's disease and amyotrophic lateral sclerosis may reflect mismetabolism of beta-amyloid induced by disparate mechanisms.

21 January 2018

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Topography of cross-sectional and longitudinal glucose metabolic deficits in Alzheimer's disease. Pathophysiologic implications

21 January 2018

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Identifying early markers of Alzheimer's disease using quantitative multiplex proteomic immunoassay panels.

21 January 2018

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Circulating biomarkers of cognitive decline and dementia

21 January 2018

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Plasma biomarkers for mild cognitive impairment and Alzheimer's disease.

21 January 2018

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Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

21 January 2018

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CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study.

21 January 2018

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Oxidatively modified, mitochondria-relevant brain proteins in subjects with Alzheimer disease and mild cognitive impairment

21 January 2018

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The Alzheimer's disease mitochondrial cascade hypothesis

21 January 2018

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Platelet amyloid precursor protein processing: a bio-marker for Alzheimer's disease

21 January 2018

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Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease

21 January 2018

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Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

21 January 2018

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Concentrations of amyloid beta protein in cerebrospinal fluid of patients with Alzheimer's disease.

21 January 2018

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Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

21 January 2018

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Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study.

21 January 2018

1 reference

Standardization of measurement of beta-amyloid(1-42) in cerebrospinal fluid and plasma.

21 January 2018

1 reference

Platelet amyloid precursor protein isoform expression in Alzheimer's disease: evidence for peripheral marker.

21 January 2018

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The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception.

21 January 2018

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Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment

21 January 2018

1 reference

Inflammatory markers and cognition in well-functioning African-American and white elders

21 January 2018

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Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer's disease.

21 January 2018

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Quantification of axonal damage in traumatic brain injury: affinity purification and characterization of cerebrospinal fluid tau proteins.

21 January 2018

1 reference

Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.

21 January 2018

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Microvascular injury and blood-brain barrier leakage in Alzheimer's disease

21 January 2018

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Clearing amyloid through the blood-brain barrier

21 January 2018

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Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia.

21 January 2018

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Elevated Platelet β-Secretase Activity in Mild Cognitive Impairment

21 January 2018

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Review and meta-analysis of biomarkers and diagnostic imaging in Alzheimer's disease

21 January 2018

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7 January 2021

The critical role of methionine 35 in Alzheimer's amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity

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7 January 2021

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

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7 January 2021

Platelets are the primary source of amyloid beta-peptide in human blood

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7 January 2021

Differential Level of Platelet Amyloid beta Precursor Protein Isoforms: An Early Marker for Alzheimer Disease

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7 January 2021

Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease.

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7 January 2021

Cerebrospinal fluid markers for Alzheimer's disease evaluated after acute ischemic stroke.

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7 January 2021

Decreased CSF amyloid beta42 and normal tau levels in dementia with Lewy bodies

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7 January 2021

Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk

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7 January 2021

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD

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7 January 2021

Increased protein and lipid oxidative damage in mitochondria isolated from lymphocytes from patients with Alzheimer's disease: insights into the role of oxidative stress in Alzheimer's disease and initial investigations into a potential biomarker fo

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7 January 2021

Identifiers

DOI

10.1002/GPS.3829

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27 August 2017

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