SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon (Q38008817)

26 August 2017

3 references

13 July 2022

22 August 2022

22 October 2022

SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon (English)

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26 August 2017

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2

Ralph S Baric

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26 August 2017

Allison L Totura

1

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26 August 2017

7 May 2012

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PubMed ID

22572391

Current opinion in virology

26 August 2017

1 June 2012

3 references

13 July 2022

22 August 2022

22 October 2022

4 references

26 August 2017

13 July 2022

22 August 2022

22 October 2022

2

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26 August 2017

3

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26 August 2017

264-275

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Mouse hepatitis coronavirus A59 nucleocapsid protein is a type I interferon antagonist

26 August 2017

1 reference

12 December 2020

Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice

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12 December 2020

Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus

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12 December 2020

Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

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12 December 2020

Molecular determinants of severe acute respiratory syndrome coronavirus pathogenesis and virulence in young and aged mouse models of human disease

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12 December 2020

SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epithelium

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12 December 2020

Interferon-stimulated genes and their antiviral effector functions

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12 December 2020

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

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12 December 2020

Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome

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12 December 2020

Pulmonary pathology of severe acute respiratory syndrome in Toronto.

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12 December 2020

A diverse range of gene products are effectors of the type I interferon antiviral response

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12 December 2020

Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice

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12 December 2020

Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs

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12 December 2020

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus

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12 December 2020

A novel coronavirus associated with severe acute respiratory syndrome

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12 December 2020

Pathology of experimental SARS coronavirus infection in cats and ferrets

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12 December 2020

Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species

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12 December 2020

Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells.

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12 December 2020

MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV.

1 reference

12 December 2020

Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex.

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12 December 2020

Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection

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12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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12 December 2020

Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1

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12 December 2020

SARS: systematic review of treatment effects

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12 December 2020

Genetic analysis of complex traits in the emerging Collaborative Cross

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12 December 2020

Recently discovered human coronaviruses

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12 December 2020

SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

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12 December 2020

Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.

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12 December 2020

A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge

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12 December 2020

SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism.

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12 December 2020

SARS-coronavirus replicates in mononuclear cells of peripheral blood (PBMCs) from SARS patients

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12 December 2020

Elucidating the molecular physiopathology of acute respiratory distress syndrome in severe acute respiratory syndrome patients

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12 December 2020

Molecular determinants for subcellular localization of the severe acute respiratory syndrome coronavirus open reading frame 3b protein

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12 December 2020

Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism

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12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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12 December 2020

Interferon-beta and interferon-gamma synergistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus (SARS-CoV).

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12 December 2020

Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model

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12 December 2020

Identification of a novel coronavirus in patients with severe acute respiratory syndrome

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12 December 2020

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

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12 December 2020

Acute lung injury review

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12 December 2020

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

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12 December 2020

Exacerbated innate host response to SARS-CoV in aged non-human primates

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12 December 2020

SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-kappaB pathway in human monocyte macrophages in vitro

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12 December 2020

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

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12 December 2020

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

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12 December 2020

Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice

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12 December 2020

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

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12 December 2020

Cytosolic surveillance and antiviral immunity

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12 December 2020

Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection

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12 December 2020

Links between innate and adaptive immunity via type I interferon

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12 December 2020

SARS coronavirus accessory proteins.

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12 December 2020

Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism.

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12 December 2020

Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus

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12 December 2020

Genomic analysis reveals age-dependent innate immune responses to severe acute respiratory syndrome coronavirus

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12 December 2020

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists

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12 December 2020

In vitro inhibition of SARS virus replication by human interferons

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12 December 2020

Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice

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12 December 2020

SARS-coronavirus protein 6 conformations required to impede protein import into the nucleus.

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12 December 2020

SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin-fixed paraffin-embedded tissues

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12 December 2020

Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice

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12 December 2020

The role of apoptosis in the pathophysiology of Acute Respiratory Distress Syndrome (ARDS): an up-to-date cell-specific review

1 reference

12 December 2020

Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus

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12 December 2020

Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection

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12 December 2020

Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome.

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12 December 2020

Murine hepatitis virus strain 1 produces a clinically relevant model of severe acute respiratory syndrome in A/J mice.

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12 December 2020

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

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12 December 2020

A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice

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12 December 2020

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

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12 December 2020

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

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12 December 2020

In vitro reconstitution of SARS-coronavirus mRNA cap methylation

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12 December 2020

Aged BALB/c mice as a model for increased severity of severe acute respiratory syndrome in elderly humans

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12 December 2020

Detection of severe acute respiratory syndrome-associated coronavirus in pneumocytes of the lung

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12 December 2020

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

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12 December 2020

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling

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12 December 2020

SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism

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12 December 2020

Murine coronavirus induces type I interferon in oligodendrocytes through recognition by RIG-I and MDA5.

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12 December 2020

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

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12 December 2020

Ultrastructure and origin of membrane vesicles associated with the severe acute respiratory syndrome coronavirus replication complex

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12 December 2020

Virology: SARS virus infection of cats and ferrets

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12 December 2020

Microarray and real-time RT-PCR analyses of differential human gene expression patterns induced by severe acute respiratory syndrome (SARS) coronavirus infection of Vero cells

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12 December 2020

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

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12 December 2020

Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain

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12 December 2020

Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters

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12 December 2020

Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys.

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12 December 2020

Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques.

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12 December 2020

Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells

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12 December 2020

Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha

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12 December 2020

Toll-like receptors: key players in antiviral immunity

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12 December 2020

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

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12 December 2020

Early Upregulation of Acute Respiratory Distress Syndrome-Associated Cytokines Promotes Lethal Disease in an Aged-Mouse Model of Severe Acute Respiratory Syndrome Coronavirus Infection

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12 December 2020

Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome.

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12 December 2020

Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Stat1.

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12 December 2020

SARS coronavirus accessory ORFs encode luxury functions

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12 December 2020

Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling

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12 December 2020

Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice

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12 December 2020

Severe acute respiratory syndrome (SARS): epidemiology and clinical features

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12 December 2020

Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane

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12 December 2020

10.1016/J.COVIRO.2012.04.004

Identifiers

DOI

1 reference

26 August 2017

0 references

1 reference

PubMed ID

22572391