TCR signaling requirements for activating T cells and for generating memory (Q38004926)

26 August 2017

TCR signaling requirements for activating T cells and for generating memory (English)

1 reference

26 August 2017

Dietmar Zehn

1

1 reference

26 August 2017

Carolyn King

series ordinal

2

1 reference

26 August 2017

Michael J Bevan

series ordinal

3

1 reference

26 August 2017

Ed Palmer

series ordinal

4

1 reference

26 August 2017

19 April 2012

1 reference

Cellular and Molecular Life Sciences

26 August 2017

1 reference

26 August 2017

69

1 reference

26 August 2017

1565-1575

1 reference

26 August 2017

10

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-012-0965-x

26 August 2017

0 references

cites work

Effector and memory T-cell differentiation: implications for vaccine development

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Effector and memory CTL differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Estimating the precursor frequency of naive antigen-specific CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Human naive and memory CD4+ T cell repertoires specific for naturally processed antigens analyzed using libraries of amplified T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Endogenous naive CD8+ T cell precursor frequency regulates primary and memory responses to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Massive expansion of antigen-specific CD8+ T cells during an acute virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

The role of programming in memory T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Persistent antigen presentation after acute vesicular stomatitis virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

In situ imaging of the endogenous CD8 T cell response to infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Cutting edge: prolonged antigen presentation after herpes simplex virus-1 skin infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

CD8 T cell expansion and memory differentiation are facilitated by simultaneous and sustained exposure to antigenic and inflammatory milieu.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Cutting edge: contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T-cell-receptor affinity and thymocyte positive selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

A constant affinity threshold for T cell tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Complete but curtailed T-cell response to very low-affinity antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Selecting and maintaining a diverse T-cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

TCR affinity and negative regulation limit autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Lack of original antigenic sin in recall CD8(+) T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Making sense of mass destruction: quantitating MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T cell killing does not require the formation of a stable mature immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T-cell-antigen recognition and the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Differential requirement for Lck during primary and memory CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Adaptors as central mediators of signal transduction in immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

The Erk2 MAPK regulates CD8 T cell proliferation and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

The cunning little vixen: Foxo and the cycle of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 signaling pathways have divergent roles in CD8(+) T cell-mediated antiviral immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

TCR signal transduction in antigen-specific memory CD8 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Mature T cells depend on signaling through the IKK complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Different T cell receptor signals determine CD8+ memory versus effector development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

mTOR regulates memory CD8 T-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Metabolism in T cell activation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Critical roles of the PI3K/Akt signaling pathway in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0965-X

A critical role for NF-kappaB transcription factors in the development of CD8+ memory-phenotype T cells

21 January 2018

1 reference

12 December 2020

Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

1 reference

12 December 2020

Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen

1 reference

12 December 2020

Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper

1 reference

12 December 2020

Caveats in the design of MHC class I tetramer/antigen-specific T lymphocytes dissociation assays

1 reference

12 December 2020

Self peptide/MHC class I complexes have a negligible effect on the response of some CD8+ T cells to foreign antigen

1 reference

12 December 2020

Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody

1 reference

12 December 2020

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

1 reference

12 December 2020

Dendritic cells and CD28 costimulation are required to sustain virus-specific CD8+ T cell responses during the effector phase in vivo.

1 reference

12 December 2020

T cell receptor antagonist peptides induce positive selection

1 reference

12 December 2020

Dynamic programming of CD8+ T lymphocyte responses

1 reference

12 December 2020

Clonal competition inhibits the proliferation and differentiation of adoptively transferred TCR transgenic CD4 T cells in response to infection

1 reference

12 December 2020

10.1007/S00018-012-0965-X

Identifiers

DOI

1 reference

26 August 2017

1 reference