Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell (Q37997409)

26 August 2017

Physiological and pathological role of the ubiquitin-proteasome system in the vascular smooth muscle cell (English)

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ubiquitin-proteasome system

26 August 2017

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author name string

Marilene Demasi

series ordinal

1

1 reference

PubMed ID

22451513

26 August 2017

Francisco R M Laurindo

series ordinal

2

1 reference

26 August 2017

26 March 2012

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26 August 2017

Cardiovascular Research

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26 August 2017

95

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26 August 2017

183-193

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26 August 2017

2

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Developmental basis of vascular smooth muscle diversity

26 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Molecular and evolutionary basis of the cellular stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Role of proteasomes in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Second generation proteasome inhibitors: carfilzomib and immunoproteasome-specific inhibitors (IPSIs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome-independent functions of ubiquitin in endocytosis and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

The N-end rule pathway and regulation by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

21 January 2018

The proteasomal system.

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Redox control of the ubiquitin-proteasome system: from molecular mechanisms to functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Mapping the murine cardiac 26S proteasome complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Glutathiolation of the proteasome is enhanced by proteolytic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Impact of ageing on proteasome structure and function in human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin-independent proteolytic functions of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Polyubiquitin is a new phenotypic marker of contractile vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proliferation unleashed: the role of Skp2 in vascular smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin-mediated control of oncogene and tumor suppressor gene products

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Transcriptional regulation of S phase kinase-associated protein 2 by NR4A orphan nuclear receptor NOR1 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

AMPKα2 deletion exacerbates neointima formation by upregulating Skp2 in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

C terminus of Hsc70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FoxO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

CHIP: a quality-control E3 ligase collaborating with molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome inhibitor PS-341 induces apoptosis through induction of endoplasmic reticulum stress-reactive oxygen species in head and neck squamous cell carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome inhibition alters neural mitochondrial homeostasis and mitochondria turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

NADPH oxidases: functions and pathologies in the vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Regulation of NAD(P)H oxidase by associated protein disulfide isomerase in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Protein disulfide isomerase overexpression in vascular smooth muscle cells induces spontaneous preemptive NADPH oxidase activation and Nox1 mRNA expression: effects of nitrosothiol exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

NAD(P)H oxidases regulate HIF-2alpha protein expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Redox regulation of human Rac1 stability by the proteasome in human aortic endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Nitric oxide regulates the 26S proteasome in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Nitric oxide increases lysine 48-linked ubiquitination following arterial injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Nitric oxide and superoxide: interference with hypoxic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

No Splicing, no dicing: non-proteolytic roles of the ubiquitin-proteasome system in transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Potential role of CYLD (Cylindromatosis) as a deubiquitinating enzyme in vascular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

miR-29b participates in early aneurysm development in Marfan syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Endoplasmic reticulum stress signaling in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

From endoplasmic-reticulum stress to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Protein dislocation from the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Mechanisms of proteasome inhibitor action and resistance in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin-proteasome pathway as a new target for the prevention of restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome inhibitor bortezomib promotes a rupture-prone plaque phenotype in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome inhibition represses unfolded protein response and Nox4, sensitizing vascular cells to endoplasmic reticulum stress-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

FoxM1 is a general target for proteasome inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Activation of specific apoptotic caspases with an engineered small-molecule-activated protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Endoplasmic reticulum stress-induced cell death mediated by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Effects of proteasome inhibition on the kidney in experimental hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Preventive effect of a proteasome inhibitor on the formation of accelerated atherosclerosis in rabbits with uremia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Smooth muscle cell apoptosis promotes vessel remodeling and repair via activation of cell migration, proliferation, and collagen synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Chronic proteasome inhibition contributes to coronary atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Targeting of the proteasome worsens atherosclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Inhibition of the ubiquitin-proteasome system: a new avenue for atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Inhibitory effect of flavonoids on 26S proteasome activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

Calcium channel blocker verapamil enhances endoplasmic reticulum stress and cell death induced by proteasome inhibition in myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVS128

21 January 2018

Identifiers

DOI

10.1093/CVR/CVS128

1 reference

26 August 2017

1 reference

PubMed ID

22451513