Designer proteins: applications of genetic code expansion in cell biology (Q37983986)

26 August 2017

Designer proteins: applications of genetic code expansion in cell biology (English)

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26 August 2017

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Lloyd Davis

1

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PubMed ID

22334143

26 August 2017

Jason W Chin

series ordinal

2

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26 August 2017

15 February 2012

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Nature Reviews Molecular Cell Biology

26 August 2017

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26 August 2017

13

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26 August 2017

168-182

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26 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/nrm3286

26 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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Selective recognition of protein tetraserine motifs with a cell-permeable, pro-fluorescent bis-boronic acid

31 March 2020

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How to obtain labeled proteins and what to do with them

31 March 2020

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31 March 2020

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Selenium incorporation using recombinant techniques

31 March 2020

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31 March 2020

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Site-specific in vivo labeling of proteins for NMR studies

31 March 2020

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Preparation of site-specifically labeled fluorinated proteins for 19F-NMR structural characterization

31 March 2020

1 reference

Site-specific incorporation of a (19)F-amino acid into proteins as an NMR probe for characterizing protein structure and reactivity.

31 March 2020

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Two-dimensional NMR and all-atom molecular dynamics of cytochrome P450 CYP119 reveal hidden conformational substates

31 March 2020

1 reference

Protein (19)F NMR in Escherichia coli

31 March 2020

1 reference

Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli

31 March 2020

1 reference

Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae.

31 March 2020

1 reference

A genetically encoded fluorescent amino acid.

31 March 2020

1 reference

A genetically encoded fluorescent amino acid

31 March 2020

1 reference

A small molecule inhibitor selective for a variant ATP-binding site of the chaperonin GroEL.

31 March 2020

1 reference

A genetically encoded infrared probe.

31 March 2020

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Localization of GroEL determined by in vivo incorporation of a fluorescent amino acid

31 March 2020

1 reference

FTIR analysis of GPCR activation using azido probes.

31 March 2020

1 reference

Tracking G-protein-coupled receptor activation using genetically encoded infrared probes.

31 March 2020

1 reference

De novo generation of mutually orthogonal aminoacyl-tRNA synthetase/tRNA pairs.

31 March 2020

1 reference

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

31 March 2020

1 reference

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31 March 2020

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Biological applications of protein splicing

31 March 2020

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Bringing chemistry to life

31 March 2020

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31 March 2020

1 reference

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31 March 2020

1 reference

Selective Staudinger modification of proteins containing p-azidophenylalanine

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A photoinducible 1,3-dipolar cycloaddition reaction for rapid, selective modification of tetrazole-containing proteins

31 March 2020

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31 March 2020

1 reference

A pyrrolysine analogue for protein click chemistry

31 March 2020

1 reference

Site-specific PEGylation of proteins containing unnatural amino acids

31 March 2020

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Oxidative coupling of peptides to a virus capsid containing unnatural amino acids

31 March 2020

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Addition of the keto functional group to the genetic code of Escherichia coli.

31 March 2020

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Generation of a bacterium with a 21 amino acid genetic code

31 March 2020

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Site-directed spin labeling of a genetically encoded unnatural amino acid

31 March 2020

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Genetic introduction of a diketone-containing amino acid into proteins.

31 March 2020

1 reference

Genetic incorporation of an aliphatic keto-containing amino acid into proteins for their site-specific modifications

31 March 2020

1 reference

Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae

31 March 2020

1 reference

In vivo incorporation of an alkyne into proteins in Escherichia coli

31 March 2020

1 reference

Genetically encoded copper-free click chemistry

31 March 2020

1 reference

Viral capsid DNA aptamer conjugates as multivalent cell-targeting vehicles

31 March 2020

1 reference

Regioselective carbon-carbon bond formation in proteins with palladium catalysis; new protein chemistry by organometallic chemistry

31 March 2020

1 reference

Site-Specific Functionalization of Proteins by Organopalladium Reactions

31 March 2020

1 reference

Palladium-mediated site-selective Suzuki–Miyaura protein modification at genetically encoded aryl halides

31 March 2020

1 reference

A genetically encoded boronate-containing amino acid

31 March 2020

1 reference

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

31 March 2020

1 reference

A Comparative Study of Bioorthogonal Reactions with Azides

31 March 2020

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31 March 2020

12 December 2020

Tetrazine-based cycloadditions: application to pretargeted live cell imaging

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Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity

31 March 2020

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31 March 2020

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

31 March 2020

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Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne

31 March 2020

1 reference

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.

31 March 2020

1 reference

Structure of bovine rhodopsin in a trigonal crystal form.

31 March 2020

1 reference

Crystal structure of opsin in its G-protein-interacting conformation

31 March 2020

1 reference

Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2)

31 March 2020

1 reference

PubMed

12 December 2020

Diels-Alder cycloaddition for fluorophore targeting to specific proteins inside living cells

1 reference

PubMed

12 December 2020

Tudor, MBT and chromo domains gauge the degree of lysine methylation

1 reference

PubMed

12 December 2020

Identifiers

DOI

10.1038/NRM3286

1 reference

26 August 2017

1 reference

PubMed ID

22334143