Chromatin insulator elements: establishing barriers to set heterochromatin boundaries (Q37983891)

26 August 2017

Chromatin insulator elements: establishing barriers to set heterochromatin boundaries (English)

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26 August 2017

Gráinne Barkess

1

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Adam West

object named as

Adam G West

series ordinal

2

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publication date

1 February 2012

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26 August 2017

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26 August 2017

4

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26 August 2017

1

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26 August 2017

67-80

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Large-scale chromatin structural domains within mitotic and interphase chromosomes in vivo and in vitro

26 August 2017

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Radial loops and helical coils coexist in metaphase chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Silencing chromatin: comparing modes and mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Identification of higher-order functional domains in the human ENCODE regions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Systematic protein location mapping reveals five principal chromatin types in Drosophila cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Plasticity in patterns of histone modifications and chromosomal proteins in Drosophila heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genome-wide association of histone H3 lysine nine methylation with CHG DNA methylation in Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Arabidopsis TFL2/LHP1 specifically associates with genes marked by trimethylation of histone H3 lysine 27.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Whole-genome analysis of histone H3 lysine 27 trimethylation in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Broad chromosomal domains of histone modification patterns in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Distinct epigenomic landscapes of pluripotent and lineage-committed human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Reassessing the abundance of H3K9me2 chromatin domains in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Histone H3-K9 methyltransferase ESET is essential for early development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The polycomb-group gene Ezh2 is required for early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The polycomb group protein Suz12 is required for embryonic stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A comprehensive map of insulator elements for the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A cis-regulatory map of the Drosophila genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Chromatin insulators: lessons from the fly.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

RNAi-independent role for Argonaute2 in CTCF/CP190 chromatin insulator function

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Insulators: many functions, many mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A position-effect assay for boundaries of higher order chromosomal domains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Transcriptional repression mediated by polycomb group proteins and other chromatin-associated repressors is selectively blocked by insulators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Boundary sequences stabilize transgene expression from subtle position effects in retroviral vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Topological constraints governing the use of the chicken HS4 chromatin insulator in oncoretrovirus vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Acetylation of histone H2B mirrors that of H4 and H3 at the chicken beta-globin locus but not at housekeeping genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Chromatin boundaries and chromatin domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Physical properties of a genomic condensed chromatin fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Retrovirus silencer blocking by the cHS4 insulator is CTCF independent

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

VEZF1 elements mediate protection from DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Recruitment of histone modifications by USF proteins at a vertebrate barrier element

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Methylation of histone H4 by arginine methyltransferase PRMT1 is essential in vivo for many subsequent histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Characterization of the chicken beta-globin insulator

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Vezf1 regulates genomic DNA methylation through its effects on expression of DNA methyltransferase Dnmt3b

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

CTCF regulates cell cycle progression of alphabeta T cells in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

CTCF: master weaver of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The role of Hox genes during vertebrate limb development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Inactive X chromosome-specific histone H3 modifications and CpG hypomethylation flank a chromatin boundary between an X-inactivated and an escape gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A TALE nuclease architecture for efficient genome editing

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

High-resolution profiling of histone methylations in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A CTCF-independent role for cohesin in tissue-specific transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The NIH Roadmap Epigenomics Mapping Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A user's guide to the encyclopedia of DNA elements (ENCODE)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genome-wide CTCF distribution in vertebrates defines equivalent sites that aid the identification of disease-associated genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

We gather together: insulators and genome organization

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Cohesins functionally associate with CTCF on mammalian chromosome arms

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Cohesin mediates transcriptional insulation by CCCTC-binding factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Cohesin mediates chromatin interactions that regulate mammalian β-globin expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Cohesin: genomic insights into controlling gene transcription and development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The c-myc insulator element and matrix attachment regions define the c-myc chromosomal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Targeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genomic imprinting: employing and avoiding epigenetic processes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Spatial organization of gene expression: the active chromatin hub.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Conserved CTCF insulator elements flank the mouse and human beta-globin loci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genomic maps and comparative analysis of histone modifications in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Both CTCF-dependent and -independent insulators are found between the mouse T cell receptor alpha and Dad1 genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Factors binding a non-classical Cis-element prevent heterochromatin effects on locus control region activity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Insulators and promoters: closer than we think

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

An insulator with barrier-element activity promotes alpha-spectrin gene expression in erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Sequences downstream of the erythroid promoter are required for high level expression of the human alpha-spectrin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Mutation of a barrier insulator in the human ankyrin-1 gene is associated with hereditary spherocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Genome Engineering With Zinc-Finger Nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

TAL effectors: customizable proteins for DNA targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

The insulator protein SU(HW) fine-tunes nuclear lamina interactions of the Drosophila genome

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FEPI.11.112

21 January 2018

Identifiers

DOI

10.2217/EPI.11.112

1 reference

26 August 2017

1 reference

PubMed ID

22332659