TGF-β: the sword, the wand, and the shield of FOXP3(+) regulatory T cells (Q37967132)

26 August 2017

TGF-β: the sword, the wand, and the shield of FOXP3(+) regulatory T cells (English)

1 reference

26 August 2017

Dat Q Tran

1

1 reference

PubMed ID

22158907

26 August 2017

language of work or name

1 reference

8 December 2011

1 reference

Journal of Molecular Cell Biology

26 August 2017

1 reference

26 August 2017

4

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26 August 2017

1

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26 August 2017

29-37

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CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner

26 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Making sense of latent TGFbeta activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cells: stability revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Role of Th1 and Th17 cells in organ-specific autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

CD4+CD25+ T cells prevent the development of organ-specific autoimmune disease by inhibiting the differentiation of autoreactive effector T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cells suppress natural killer cells during plasmid DNA vaccination in mice, blunting the CD8+ T cell immune response by the cytokine TGFbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

In vitro and in vivo down-regulation of regulatory T cell activity with a peptide inhibitor of TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Transforming growth factor-beta in T-cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Autocrine transforming growth factor-β1 promotes in vivo Th17 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cell plasticity: beyond the controversies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Involvement of phosphatidylinositol 3'-kinase in stem-cell-factor-induced phospholipase D activation and arachidonic acid release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Latent-TGF-beta: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta: a master of all T cell trades

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Transforming growth factor-beta signaling curbs thymic negative selection promoting regulatory T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

GARP: a key receptor controlling FOXP3 in human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

"Infectious" transplantation tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Effects on serum hormone levels of low-dose estrogen in place of placebo during the hormone-free interval of an oral contraceptive

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Stability of the regulatory T cell lineage in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulatory T cells: how do they suppress immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

The suppressive effect of CD25+Treg cells on Th1 differentiation requires cell-cell contact partially via TGF-β production

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Mechanisms of foxp3+ T regulatory cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

The resurrection of T cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

The critical contribution of TGF-beta to the induction of Foxp3 expression and regulatory T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Latent TGF-β structure and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Critical role of regulatory T cells in Th17-mediated minor antigen-disparate rejection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Transforming growth factor-beta: innately bipolar

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

The kiss of death: interrupted by NK-cell close encounters of another kind

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Identification of a regulatory T cell specific cell surface molecule that mediates suppressive signals and induces Foxp3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Absence of integrin-mediated TGFbeta1 activation in vivo recapitulates the phenotype of TGFbeta1-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Plasticity of CD4+ T cell lineage differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJMCB%2FMJR033

21 January 2018

Identifiers

DOI

10.1093/JMCB/MJR033

1 reference

26 August 2017

1 reference

PubMed ID

22158907