Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing (Q37931183)

25 August 2017

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title

Rational engineering of Escherichia coli strains for plasmid biopharmaceutical manufacturing (English)

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25 August 2017

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Gabriel A Monteiro

4

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author name string

Geisa A L Gonçalves

1

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25 August 2017

Diana M Bower

2

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25 August 2017

Duarte M F Prazeres

3

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25 August 2017

Kristala L J Prather

5

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25 August 2017

publication date

13 September 2011

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25 August 2017

published in

Biotechnology Journal

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25 August 2017

volume

7

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25 August 2017

issue

2

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25 August 2017

page(s)

251-261

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DNA vaccines: an historical perspective and view to the future

25 August 2017

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Inactivating FruR global regulator in plasmid-bearing Escherichia coli alters metabolic gene expression and improves growth rate.

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Enhancement of plasmid DNA yields during fed-batch culture of a fruR-knockout Escherichia coli strain

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Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha).

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E. coli host strains significantly affect the quality of small scale plasmid DNA preparations used for sequencing

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Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production

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21 January 2018

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Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines.

21 January 2018

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Deletion formation mutations in plasmid expression vectors are unfavored by runaway amplification conditions and differentially selected under kanamycin stress

21 January 2018

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Emergent properties of reduced-genome Escherichia coli.

21 January 2018

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Gene expression profiling by DNA microarrays and metabolic fluxes in Escherichia coli

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Effects of fermentation strategy on the characteristics of plasmid DNA production

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21 January 2018

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21 January 2018

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Separation of supercoiled from open circular forms of plasmid DNA, and biological activity detection

21 January 2018

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Plasmid DNA supercoiling and gyrase activity in Escherichia coli wild-type and rpoS stationary-phase cells.

21 January 2018

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pFARs, plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells

21 January 2018

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Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110

21 January 2018

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21 January 2018

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Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

21 January 2018

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Marker-free plasmids for gene therapeutic applications—Lack of antibiotic resistance gene substantially improves the manufacturing process

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIOT.201100062

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25 August 2017

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