Plasmid DNA fermentation strain and process-specific effects on vector yield, quality, and transgene expression (Q39839158)

15 September 2017

Plasmid DNA fermentation strain and process-specific effects on vector yield, quality, and transgene expression (English)

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15 September 2017

Aaron E Carnes

1

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15 September 2017

Jeremy M Luke

2

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15 September 2017

Justin M Vincent

3

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15 September 2017

Angela Schukar

4

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15 September 2017

Sheryl Anderson

5

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15 September 2017

Clague P Hodgson

6

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15 September 2017

James A Williams

7

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15 September 2017

language of work or name

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1 February 2011

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Biotechnology and Bioengineering

15 September 2017

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15 September 2017

108

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15 September 2017

2

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15 September 2017

354-363

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Bacterial DNA methylation and gene transfer efficiency.

15 September 2017

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Isolation of Supercoiled Colicinogenic Factor E 1 DNA Sensitive to Ribonuclease and Alkali

21 January 2018

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DNA vaccine manufacture: scale and quality

21 January 2018

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Plasmid DNA manufacturing technology

21 January 2018

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Inducible Escherichia coli fermentation for increased plasmid DNA production.

21 January 2018

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The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study

21 January 2018

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Epigenetic regulation of the bacterial cell cycle

21 January 2018

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Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines.

21 January 2018

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One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

21 January 2018

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Characterization of the acetate-producing pathways in Escherichia coli

21 January 2018

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Presence of 5-methylcytosine in CC(A/T)GG sequences (Dcm methylation) in DNAs from different bacteria

21 January 2018

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Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteria

21 January 2018

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Intracellular DNA recognition

21 January 2018

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Genome sequences of Escherichia coli B strains REL606 and BL21(DE3).

21 January 2018

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Down-regulation of acetate pathway through antisense strategy in Escherichia coli: improved foreign protein production.

21 January 2018

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High-yield production of pBR322-derived plasmids intended for human gene therapy by employing a temperature-controllable point mutation

21 January 2018

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Mammalian cis-reporting plasmid may alter activities due to the derivation of host Escherichia coli strains

21 January 2018

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Development of a highly productive and scalable plasmid DNA production platform.

21 January 2018

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Improved antibiotic-free DNA vaccine vectors utilizing a novel RNA based plasmid selection system

21 January 2018

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Improved antibiotic-free plasmid vector design by incorporation of transient expression enhancers

21 January 2018

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Effects of fermentation strategy on the characteristics of plasmid DNA production

21 January 2018

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Effect of methylated adenine in plasmid DNA on transgene expression in mice

21 January 2018

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Glucose metabolism at high density growth of E. coli B and E. coli K: differences in metabolic pathways are responsible for efficient glucose utilization in E. coli B as determined by microarrays and Northern blot analyses

21 January 2018

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Modified Escherichia coli B (BL21), a superior producer of plasmid DNA compared with Escherichia coli K (DH5alpha).

21 January 2018

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Identification and characterization of IS1 transposition in plasmid amplification mutants of E. coli clones producing DNA vaccines.

21 January 2018

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Differences in macrophage activation by bacterial DNA and CpG-containing oligonucleotides

21 January 2018

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DNA plasmid production in different host strains of Escherichia coli

21 January 2018

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Asymmetry of Dam remethylation on the leading and lagging arms of plasmid replicative intermediates

21 January 2018

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Bacterial DNA activates human neutrophils by a CpG‐independent pathway

21 January 2018

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Cytokine induction by a bacterial DNA-specific modified base

21 January 2018

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Plasmid DNA vaccine vector design: impact on efficacy, safety and upstream production

21 January 2018

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Generic plasmid DNA production platform incorporating low metabolic burden seed-stock and fed-batch fermentation processes.

21 January 2018

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Marker-free plasmids for gene therapeutic applications—Lack of antibiotic resistance gene substantially improves the manufacturing process

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIT.22936

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15 September 2017

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