Cancer stem cell theory in gastrointestinal malignancies: recent progress and upcoming challenges (Q37920789)

25 August 2017

1 reference

title

Cancer stem cell theory in gastrointestinal malignancies: recent progress and upcoming challenges (English)

1 reference

25 August 2017

neoplastic stem cells

1 reference

9

Masaki Mori

1 reference

25 August 2017

8

Yuichiro Doki

1 reference

25 August 2017

2

Hideshi Ishii

1 reference

25 August 2017

7

Taroh Satoh

1 reference

25 August 2017

1

Dyah Laksmi Dewi

1 reference

25 August 2017

4

Shinpei Nishikawa

1 reference

25 August 2017

3

Yoshihiro Kano

1 reference

25 August 2017

5

Naotsugu Haraguchi

1 reference

25 August 2017

Daisuke Sakai

6

1 reference

25 August 2017

20 August 2011

1 reference

Journal of Gastroenterology

25 August 2017

1 reference

25 August 2017

46

1 reference

25 August 2017

1145-1157

1 reference

25 August 2017

10

1 reference

Is tumor growth sustained by rare cancer stem cells or dominant clones?

25 August 2017

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Stem cells, cancer, and cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Heterogeneity in cancer: cancer stem cells versus clonal evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Prospective identification of tumorigenic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Tumour stem cells and drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Association of reactive oxygen species levels and radioresistance in cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Characterization of a side population of cancer cells from human gastrointestinal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Critical appraisal of the side population assay in stem cell and cancer stem cell research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

CD133, a novel marker for human prostatic epithelial stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Direct isolation of human central nervous system stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification and expansion of human colon-cancer-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Tumorigenic role of podoplanin in esophageal squamous-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of gastric cancer stem cells using the cell surface marker CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of human brain tumour initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Significance of CD90+ cancer stem cells in human liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of local and circulating cancer stem cells in human liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

CD13 is a therapeutic target in human liver cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Isolation of multipotent progenitor cells from human fetal liver capable of differentiating into liver and mesenchymal lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of pancreatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Efficient tumour formation by single human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Cells of origin in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Stem cells, aging, and cancer: inevitabilities and outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Module map of stem cell genes guides creation of epithelial cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The canonical Notch signaling pathway: unfolding the activation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The role of notch signaling in the development of intrahepatic bile ducts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Wnt signalling in stem cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Roles of TGF-beta family signaling in stem cell renewal and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

TGFbeta signalling: a complex web in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The epigenomics of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Aberrant epigenetic landscape in cancer: how cellular identity goes awry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Global histone modification patterns predict risk of prostate cancer recurrence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Dicer is essential for mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

MicroRNAs control intestinal epithelial differentiation, architecture, and barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Human embryonic stem cells express a unique set of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Impaired microRNA processing enhances cellular transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

miR-130b Promotes CD133(+) liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Stromal fibroblasts in cancer initiation and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Stem cells and niches: mechanisms that promote stem cell maintenance throughout life

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Stem cells and their niches

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

A perivascular niche for brain tumor stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

O2 regulates stem cells through Wnt/β-catenin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Identification of selective inhibitors of cancer stem cells by high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

let-7 regulates self renewal and tumorigenicity of breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-011-0442-6

Tumor heterogeneity and drug resistance

21 January 2018

1 reference

12 December 2020

miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1.

1 reference

12 December 2020

Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells

1 reference

12 December 2020

Cancer stem/progenitor cells are highly enriched in CD133+CD44+ population in hepatocellular carcinoma

1 reference

12 December 2020

CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors

1 reference

12 December 2020

Salinomycin selectively targets 'CD133+' cell subpopulations and decreases malignant traits in colorectal cancer lines

1 reference

12 December 2020

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM.

1 reference

12 December 2020

Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.

1 reference

12 December 2020

AC133, a novel marker for human hematopoietic stem and progenitor cells

1 reference

12 December 2020

10.1007/S00535-011-0442-6

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

21858638