Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. (Q40252270)

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27 December 2019

title

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9 (English)

1 reference

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27 December 2019

1 reference

1

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27 December 2019

11

Todd R Golub

1 reference

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27 December 2019

9

William C Hahn

1 reference

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27 December 2019

author name string

David Twomey

2

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27 December 2019

Zhaohui Feng

3

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27 December 2019

Matthew C Stubbs

4

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27 December 2019

Yingzi Wang

5

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27 December 2019

Joerg Faber

6

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27 December 2019

Jason E Levine

7

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27 December 2019

Jing Wang

8

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27 December 2019

D Gary Gilliland

10

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27 December 2019

Scott A Armstrong

12

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27 December 2019

publication date

16 July 2006

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27 December 2019

language of work or name

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1 reference

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27 December 2019

volume

442

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27 December 2019

issue

7104

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27 December 2019

page(s)

818-822

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Stem cells, cancer, and cancer stem cells

27 December 2019

cites work

1 reference

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21 January 2018

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Self-renewal and solid tumor stem cells

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Identification of human brain tumour initiating cells

21 January 2018

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

21 January 2018

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MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

21 January 2018

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21 January 2018

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A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

21 January 2018

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Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL

21 January 2018

1 reference

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An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

21 January 2018

1 reference

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Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.

21 January 2018

1 reference

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Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis

21 January 2018

1 reference

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"Stemness": transcriptional profiling of embryonic and adult stem cells

21 January 2018

1 reference

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Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

21 January 2018

1 reference

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

21 January 2018

1 reference

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

21 January 2018

1 reference

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Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.

21 January 2018

1 reference

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

21 January 2018

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Gene expression profiling of pediatric acute myelogenous leukemia

21 January 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

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ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation

21 January 2018

1 reference

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Hox regulation of normal and leukemic hematopoietic stem cells.

21 January 2018

1 reference

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MLL associates specifically with a subset of transcriptionally active target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04980

Global and Hox-specific roles for the MLL1 methyltransferase

21 January 2018

1 reference

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Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

21 January 2018

1 reference

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An Mll-dependent Hox program drives hematopoietic progenitor expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04980

MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04980

inferred from DOI database lookup

7 January 2021

based on heuristic

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE04980

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE04980

1 reference

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Dimensions publication ID

27 December 2019

1030873412

0 references

1 reference